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Protein
Submitted name:

Heat shock 70 (HSP70) protein

Gene

cgd2_20

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei214ADP; via amide nitrogenCombined sources1
Binding sitei352ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 26ADPCombined sources3
Nucleotide bindingi24 – 26ATP analogCombined sources3
Nucleotide bindingi214 – 216ATP analogCombined sources3
Nucleotide bindingi281 – 288ADPCombined sources8
Nucleotide bindingi281 – 288ATP analogCombined sources8
Nucleotide bindingi352 – 355ADPCombined sources4

GO - Molecular functioni

Keywordsi

Biological processStress responseImported
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Heat shock 70 (HSP70) proteinImported
Gene namesi
ORF Names:cgd2_20Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
Proteomesi
  • UP000006726 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiCryptoDB:cgd2_20.

Interactioni

Protein-protein interaction databases

STRINGi353152.XP_625373.1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3KVGX-ray2.15A/B15-396[»]
3L4IX-ray2.20A/B15-396[»]
3L6QX-ray2.29A/B15-396[»]
ProteinModelPortaliQ5CPP8.
SMRiQ5CPP8.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5CPP8.

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
HOGENOMiHOG000228135.
InParanoidiQ5CPP8.
KOiK03283.
OMAiAYTKNQD.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiView protein in InterPro
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiView protein in PROSITE
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5CPP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ILIEIQKNKM TSSEGPAIGI DLGTTYSCVG VWRNDTVDIV PNDQGNRTTP
60 70 80 90 100
SYVAFTETER LIGDAAKNQV ARNPENTVFD AKRLIGRKFD DQAVQSDMTH
110 120 130 140 150
WPFKVVRGPK DKPIISVNYL GEKKEFHAEE ISAMVLQKMK EISEAYLGRQ
160 170 180 190 200
IKNAVVTVPA YFNDSQRQAT KDAGAIAGLN VMRIINEPTA AAIAYGLDKK
210 220 230 240 250
GTGERNVLIF DLGGGTFDVS LLTIEDGIFE VKATAGDTHL GGEDFDNRLV
260 270 280 290 300
EFCVQDFKRK NRGMDLTTNA RALRRLRTQC ERAKRTLSSS TQATIELDSL
310 320 330 340 350
YEGIDYSVAI SRARFEELCA DYFRATLAPV EKVLKDAGMD KRSVHDVVLV
360 370 380 390 400
GGSTRIPKVQ ALIQEFFNGK EPCKAINPDE AVAYGAAVQA AILNGEQSSA
410 420 430 440 450
VQDLLLLDVA PLSLGLETAG GVMTKLIERN TTIPAKKTQV FTTYADNQSG
460 470 480 490 500
VLIQVYEGER AMTKDNHLLG KFHLDGIPPA PRGVPQIEVT FDIDANGILN
510 520 530 540 550
VSAVDKSTGK SSKITITNDK GRLSKDDIER MVNDAEKYKG EDEQNRLKIE
560 570 580 590 600
AKNSLENYLY NMRNTIQEPK VKEKLSQSEI DEAEKKIKDA LDWLEHNQTA
610 620 630 640 650
EKDEFEHQQK EIETHMNPLM MKIYSAEGGM PGGMPGGMPG GMPGGMPGGM
660 670 680
PGGMPGGMPG GMPGGMPGGM PGSNGPTVEE VD
Length:682
Mass (Da):74,457
Last modified:April 12, 2005 - v1
Checksum:iB9F5CE62B0948B7C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000013 Genomic DNA. Translation: EAK87398.1.
RefSeqiXP_625373.1. XM_625373.1.

Genome annotation databases

EnsemblProtistsiEAK87398; EAK87398; cgd2_20.
GeneIDi3372348.
KEGGicpv:cgd2_20.

Similar proteinsi

Entry informationi

Entry nameiQ5CPP8_CRYPI
AccessioniPrimary (citable) accession number: Q5CPP8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: August 30, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported