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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

cgd2_210

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei106NADUniRule annotation1
Binding sitei132SubstrateUniRule annotation1
Binding sitei165NAD; via amide nitrogenUniRule annotation1
Active sitei216Proton acceptorUniRule annotation1
Binding sitei283NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 23NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:cgd2_210Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
Proteomesi

Organism-specific databases

EuPathDBiCryptoDB:cgd2_210

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi353152.XP_625390.1

Structurei

3D structure databases

ProteinModelPortaliQ5CPN1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 184NAD_Gly3P_dh_NInterPro annotationAdd BLAST172
Domaini205 – 361NAD_Gly3P_dh_CInterPro annotationAdd BLAST157

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni283 – 284Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
HOGENOMiHOG000246855
InParanoidiQ5CPN1
KOiK00006
OMAiPHQFIHK

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit

Sequencei

Sequence statusi: Complete.

Q5CPN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCLRQHLRCS SLKVTIFGAG SFGSAISCVV GYNTERTLIF NSEVKLWLYD
60 70 80 90 100
ERLESGEYLA DVINRDHVNV KYLPDFKLPN NIRAVTDLKE ACEDCNLMIF
110 120 130 140 150
VIPSQFIRSV ASQIRKLDID FSRAVRAVSL TKGFLVENGH PFLISKIIEE
160 170 180 190 200
ELGIDCCVLS GANVASGLAA KEFGEATLAC SDYDDAYIWQ YLFDTPWFKI
210 220 230 240 250
DCVPDVICTE LFGGLKNIIA LLVGMIQGLG CGTNTVAAVM RLGVLEMILY
260 270 280 290 300
GSIFFNIRSS IMTRVFFESC GIADLVTTCL GGRNVRGGKA FTLSNGQKPW
310 320 330 340 350
EEIEAEVTGG QHLAGLVTLK EINETLEVLL IEKSIDVDKH FPLFRSCFKI
360 370 380 390 400
AYTGAPPRSL IDILGRNELR ELRFVPSGLL SLIDDSPNHG EVMQRSSSRQ
410
VGSLILSKTQ SCMQYE
Length:416
Mass (Da):46,077
Last modified:April 12, 2005 - v1
Checksum:i9CFAD9998DB3A140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000013 Genomic DNA Translation: EAK87381.1
RefSeqiXP_625390.1, XM_625390.1

Genome annotation databases

EnsemblProtistsiEAK87381; EAK87381; cgd2_210
GeneIDi3372365
KEGGicpv:cgd2_210

Similar proteinsi

Entry informationi

Entry nameiQ5CPN1_CRYPI
AccessioniPrimary (citable) accession number: Q5CPN1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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