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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

cgd2_210

Organism
Cryptosporidium parvum (strain Iowa II)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei132 – 1321SubstrateUniRule annotation
Active sitei216 – 2161Proton acceptorUniRule annotation

GO - Molecular functioni

  1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. glycerol-3-phosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:cgd2_210Imported
OrganismiCryptosporidium parvum (strain Iowa II)Imported
Taxonomic identifieri353152 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaCryptosporidiidaeCryptosporidium
ProteomesiUP000006726 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiCryptoDB:cgd2_210.

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5807.cgd2_210.

Structurei

3D structure databases

ProteinModelPortaliQ5CPN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiQ5CPN1.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5CPN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCLRQHLRCS SLKVTIFGAG SFGSAISCVV GYNTERTLIF NSEVKLWLYD
60 70 80 90 100
ERLESGEYLA DVINRDHVNV KYLPDFKLPN NIRAVTDLKE ACEDCNLMIF
110 120 130 140 150
VIPSQFIRSV ASQIRKLDID FSRAVRAVSL TKGFLVENGH PFLISKIIEE
160 170 180 190 200
ELGIDCCVLS GANVASGLAA KEFGEATLAC SDYDDAYIWQ YLFDTPWFKI
210 220 230 240 250
DCVPDVICTE LFGGLKNIIA LLVGMIQGLG CGTNTVAAVM RLGVLEMILY
260 270 280 290 300
GSIFFNIRSS IMTRVFFESC GIADLVTTCL GGRNVRGGKA FTLSNGQKPW
310 320 330 340 350
EEIEAEVTGG QHLAGLVTLK EINETLEVLL IEKSIDVDKH FPLFRSCFKI
360 370 380 390 400
AYTGAPPRSL IDILGRNELR ELRFVPSGLL SLIDDSPNHG EVMQRSSSRQ
410
VGSLILSKTQ SCMQYE
Length:416
Mass (Da):46,077
Last modified:April 12, 2005 - v1
Checksum:i9CFAD9998DB3A140
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000013 Genomic DNA. Translation: EAK87381.1.
RefSeqiXP_625390.1. XM_625390.1.

Genome annotation databases

GeneIDi3372365.
KEGGicpv:cgd2_210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEE01000013 Genomic DNA. Translation: EAK87381.1.
RefSeqiXP_625390.1. XM_625390.1.

3D structure databases

ProteinModelPortaliQ5CPN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5807.cgd2_210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3372365.
KEGGicpv:cgd2_210.

Organism-specific databases

EuPathDBiCryptoDB:cgd2_210.

Phylogenomic databases

HOGENOMiHOG000246855.
InParanoidiQ5CPN1.
KOiK00006.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Iowa IIImported.

Entry informationi

Entry nameiQ5CPN1_CRYPI
AccessioniPrimary (citable) accession number: Q5CPN1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: April 29, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.