Q5CPK1 (Q5CPK1_CRYPI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913

Gene names

ORF Names:

cgd6_80 EMBL EAK87357.1

Organism

Cryptosporidium parvum (strain Iowa II) [Complete proteome]

Taxonomic identifier

353152 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Conoidasida › Coccidia › Eucoccidiorida › Eimeriorina › Cryptosporidiidae › Cryptosporidium › Cryptosporidium parvum

Protein attributes

Sequence length	460 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913
Subcellular location	Nucleus By similarity PIRNR PIRNR037913.
Sequence similarities	Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Ontologies

Keywords
Biological process	Transcription Transcription regulation PIRNR PIRNR037913
Cellular component	Nucleus PIRNR PIRNR037913
Molecular function	Chromatin regulator PIRNR PIRNR037913 Hydrolase PIRNR PIRNR037913 SAAS SAAS000286
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	histone H3 deacetylation Inferred from electronic annotation. Source: GOC histone H4 deacetylation Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K18 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K9 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H4-K16 specific) Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL EAK87357.1

Sequences

	Sequence		Length	Mass (Da)
	Q5CPK1 [UniParc]. Last modified April 12, 2005. Version 1. Checksum: 145845DA7A4A3051	FASTA	460	52,200
	10 20 30 40 50 60 ILLVSHLNNI VVISLKMAKR VSYFYDGDIG SYYYGPGHPM KPQRIRMAHN LILSYDLYKH 70 80 90 100 110 120 MEIYKPHKSP QSELVYFHEE DYINFLSSIN PDNSKDFGLQ LKRFNLGETT DCPVFDGLFE 130 140 150 160 170 180 FQQICAGGSI DGAYKLNNEQ SDICINWSGG LHHAKRSEAS GFCYINDIVL GILELLKYHA 190 200 210 220 230 240 RVMYIDIDVH HGDGVEEAFY LSHRVLTVSF HKFGEFFPGT GDITDIGVAQ GKYYSVNVPL 250 260 270 280 290 300 NDGIDDDSFL SLFKPIISKC IEVYRPGAIV LQCGADSVRG DRLGRFNLSI KGHAECVEFC 310 320 330 340 350 360 KKFNIPLLIL GGGGYTIRNV ARTWAYETAT ILDRTDLISD NIPLNDYYDY FAPDFKLHIP 370 380 390 400 410 420 PLNLPNMNSP EHLEKIKAKV IDNLRYLEHA PGVEFAYVPS DFFDREASNL QKQEDEEREE 430 440 450 460 ELSSWQGGGR AAGSTESQGN HNEKPKSSRK LQKEHASEFY

References

[1]

"Complete genome sequence of the apicomplexan, Cryptosporidium parvum." Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G., Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P., Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L., Anantharaman V., Aravind L., Kapur V. Science 304:441-445(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Iowa II.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAEE01000014 Genomic DNA. Translation: EAK87357.1.
RefSeq	XP_625348.1. XM_625348.1.
3D structure databases
ProteinModelPortal	Q5CPK1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3375652.
KEGG	cpv:cgd6_80.
Organism-specific databases
EuPathDB	CryptoDB:cgd6_80.
Phylogenomic databases
HOGENOM	HOG000225180.
KO	K06067.
ProtClustDB	PTZ00063.
Family and domain databases
Gene3D	3.40.800.20. 1 hit.
InterPro	IPR000286. His_deacetylse. IPR003084. His_deacetylse_1. IPR023801. His_deacetylse_dom. [Graphical view]
PANTHER	PTHR10625. PTHR10625. 1 hit.
Pfam	PF00850. Hist_deacetyl. 1 hit. [Graphical view]
PIRSF	PIRSF037913. His_deacetylse_1. 1 hit.
PRINTS	PR01270. HDASUPER. PR01271. HISDACETLASE.
ProtoNet	Search...
Other
BindingDB	Q5CPK1.

Entry information

Entry name

Q5CPK1_CRYPI

Accession

Primary (citable) accession number: Q5CPK1

Entry history

Integrated into UniProtKB/TrEMBL:	April 12, 2005
Last sequence update:	April 12, 2005
Last modified:	March 6, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)