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Q5BL65

- Q5BL65_XENTR

UniProt

Q5BL65 - Q5BL65_XENTR

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Protein
Submitted name:

ATPase, H+/K+ exchanging, alpha polypeptide

Gene

atp12a

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cation-transporting ATPase activity Source: InterPro
  3. metal ion binding Source: InterPro
  4. monovalent inorganic cation transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. ATP biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATPase, H+/K+ exchanging, alpha polypeptideImported
Gene namesi
Name:atp12aImported
Synonyms:atp4aImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-5771626. atp12a.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000033243.

Structurei

3D structure databases

ProteinModelPortaliQ5BL65.
SMRiQ5BL65. Positions 36-1033.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG004298.
KOiK01544.

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR005775. ATPase_P-typ_Na/K_IIC.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BL65-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSEKPPEPY IVPMDDQKAN TEKKKNKLFG KKKGNKSGKK VDTLKKELEI
60 70 80 90 100
NDHNLSIEEL EKKYNVDIKV GQPQQTADEL FARDGPNRLS PPKGTPEIVK
110 120 130 140 150
FMLLMAGGFS IVFWIGSILC FIAYGLQVAQ DPTVSKDNLW LALILIAVVV
160 170 180 190 200
MTALFAYYQE AKSTNIMAGF KNMVPQQALV LRDGKRVELV AEKLVVGDIV
210 220 230 240 250
FIKGGDKIPA DLRMLESAGC KVDNSSLTGE SEPQARGTEC TDENPLETKN
260 270 280 290 300
LAFFSTTCLE GTASGIVINT GDRTVIGRIA NLASQVGNQK TPIALEIEHF
310 320 330 340 350
VHMISGLAVG VGILFFIISI SMGYSALNAI IFCIGIVVAY VPEGLLATVT
360 370 380 390 400
VCLSLTAKRM AKKNCLVKNL EAVETLGSTS VICSDKTGTL TQNRMTVAHM
410 420 430 440 450
WFDNIIHNAD TTEDQSGEAF DQSSPSWKAL LRIATLCNRA EFLACAEDVP
460 470 480 490 500
INKRQVNGDA SEAALLKFSE QLQGNVSDVR ARNKKVSEIP FNSSNKYQVS
510 520 530 540 550
IHIPENPAEK GYLLVMKGAP ERILDRCETI MIAGQEWPLD EEMKENFQNA
560 570 580 590 600
YMTLGGLGER VLGFCQLSLP HDVYGPGYPF DTENVNFPLS GLCFVGLISM
610 620 630 640 650
IDPPRSSVPD AVMKCRSSGI KVIMVTGDHP ITAKAIARCV GIISSTSETV
660 670 680 690 700
EDIAERLGIP VEQVNPREAC ACVVNGGEII DMTSDELDDV LRHHQEIVFA
710 720 730 740 750
RTSPQQKLLI VEGCQRLGAI VAVTGDGVND SPALKKADIG VAMGIAGSDA
760 770 780 790 800
AKHSADMILL DDNFASIVTG VEEGRLIFDN LKKSISYTVT KNIPEMIPFM
810 820 830 840 850
VYVIISCPLP LGTITILFIE LGTDIIPSIA LAYEKAENDI MLRKPRNPRK
860 870 880 890 900
DRLVNQQLLT YSYFHIAAME SYAGFVNYFT VMAQQGFLPI TLIGLRAPWE
910 920 930 940 950
DKNIQELEDS YGQEWTYTQR LHQEWYCYSA FFISIVVCQM MNTCIRKTRR
960 970 980 990 1000
NTILSRNFFR NKVIFIGLLS QVAIGVFLCY CPGMDDALHF MPIRVQYWFV
1010 1020 1030
SIEYTILILV YDELRKLLIR TFPGSWVDKE LYY
Length:1,033
Mass (Da):114,400
Last modified:April 12, 2005 - v1
Checksum:iFBF36D282BA28915
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090586 mRNA. Translation: AAH90586.1.
RefSeqiNP_001025550.1. NM_001030379.1.
UniGeneiStr.45363.

Genome annotation databases

GeneIDi594945.
KEGGixtr:594945.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090586 mRNA. Translation: AAH90586.1 .
RefSeqi NP_001025550.1. NM_001030379.1.
UniGenei Str.45363.

3D structure databases

ProteinModelPortali Q5BL65.
SMRi Q5BL65. Positions 36-1033.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 8364.ENSXETP00000033243.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 594945.
KEGGi xtr:594945.

Organism-specific databases

CTDi 479.
Xenbasei XB-GENE-5771626. atp12a.

Phylogenomic databases

HOVERGENi HBG004298.
KOi K01544.

Family and domain databases

Gene3Di 1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProi IPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR005775. ATPase_P-typ_Na/K_IIC.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view ]
Pfami PF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SMARTi SM00831. Cation_ATPase_N. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsi TIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: EmbryoImported.

Entry informationi

Entry nameiQ5BL65_XENTR
AccessioniPrimary (citable) accession number: Q5BL65
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: November 26, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)