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Protein

Homeobox protein cut-like

Gene

Cux1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1150 – 1209HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationImported
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein cut-likeUniRule annotation
Gene namesi
Name:Cux1Imported
Synonyms:Cutl1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88568. Cux1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ5BL05.
PeptideAtlasiQ5BL05.

Expressioni

Gene expression databases

GenevisibleiQ5BL05. MM.

Structurei

3D structure databases

ProteinModelPortaliQ5BL05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini451 – 538CUTInterPro annotationAdd BLAST88
Domaini840 – 927CUTInterPro annotationAdd BLAST88
Domaini1023 – 1110CUTInterPro annotationAdd BLAST88
Domaini1148 – 1208HomeoboxInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili112 – 196Sequence analysisAdd BLAST85
Coiled coili201 – 228Sequence analysisAdd BLAST28
Coiled coili237 – 274Sequence analysisAdd BLAST38
Coiled coili296 – 355Sequence analysisAdd BLAST60

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotationImported

Phylogenomic databases

eggNOGiKOG0963. Eukaryota.
KOG2252. Eukaryota.
ENOG410XPRP. LUCA.
HOVERGENiHBG051268.
KOiK09313.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR003350. CUT_dom.
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
PfamiView protein in Pfam
PF02376. CUT. 3 hits.
PF00046. Homeobox. 1 hit.
SMARTiView protein in SMART
SM01109. CUT. 3 hits.
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 3 hits.
PROSITEiView protein in PROSITE
PS51042. CUT. 3 hits.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5BL05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR
60 70 80 90 100
EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP
110 120 130 140 150
DPVPALDVGQ QLEIKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKSQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK
210 220 230 240 250
LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA
260 270 280 290 300
NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE
310 320 330 340 350
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLNAKNSTLK
360 370 380 390 400
QLEEKLKGQA DYEEVKKELN TLKSMEFAPS EGAGTQDSTK PLEVLLLEKN
410 420 430 440 450
RSLQSENATL RISNSDLSGP YSTNSISSPS PLQQSPDVNG MAPSPSQSES
460 470 480 490 500
AGSISEGEEI DTAEIARQVK EQLIKHNIGQ RIFGHYVLGL SQGSVSEILA
510 520 530 540 550
RPKPWNKLTV RGKEPFHKMK QFLSDEQNIL ALRSIQGRQR ENPGQSLNRL
560 570 580 590 600
FQEVPKRRNG SEGNITTRIR ASETGSDEAI KSILEQAKRE LQVQKTAEPV
610 620 630 640 650
QTSSTSSSGN SDDAIRSILQ QARREMEAQQ AALDPALKPA PLSQPDLTIL
660 670 680 690 700
TPKHLSASPM STVSTYPPLA ISLKKTPAAP ETSTAALPSA PALKKEAQDV
710 720 730 740 750
PTLDPPGSAD AAQGVLRPMK SELVRGSTWK DPWWSPIQPE RRNLTSSEET
760 770 780 790 800
KADETTASGK ERAGSSQPRA ERSQLQGPSA SAEYWKEWPS AESPYSQSSE
810 820 830 840 850
LSLTGASRSE TPQNSPLPSS PIVPMAKPAK PSVPPLTPEQ YEVYMYQEVD
860 870 880 890 900
TIELTRQVKE KLAKNGICQR IFGEKVLGLS QGSVSDMLSR PKPWSKLTQK
910 920 930 940 950
GREPFIRMQL WLNGELGQGV LPVQGQQQGP VLHSVASLQD PLQQGCVSSE
960 970 980 990 1000
STPKTSASCS PAPESPMSSS ESVKSLTELV QQPCPAIETS KEGKPPEPSD
1010 1020 1030 1040 1050
PPASDSQPTT PLPLSGHSAL SIQELVAMSP ELDTYGITKR VKEVLTDNNL
1060 1070 1080 1090 1100
GQRLFGETIL GLTQGSVSDL LARPKPWHKL SLKGREPFVR MQLWLNDPNN
1110 1120 1130 1140 1150
VEKLMDMKRM EKKAYMKRRH SSVSDSQPCE PPSVGIDYSQ GASPHPQHQL
1160 1170 1180 1190 1200
KKPRVVLAPE EKEALKRAYQ QKPYPSPKTI EELATQLNLK TSTVINWFHN
1210 1220 1230 1240 1250
YRSRIRRELF IEEIQAGSQG QAGASDSPSA RSSRAAPSSE GDSCDGVEAT
1260 1270 1280 1290 1300
DAEEPGGNIV ATKSQGGLAE VAAAPADREE ATQPAEKAKA QPLCSGTPGQ
1310 1320 1330 1340 1350
DDGEDASRPR PLPEGLADAP APVPSLAAPA AGEDAATSAT APATATEAPG
1360 1370 1380 1390 1400
AARAGPAERS SALPSTSAPA NAPARRPSSL QSLFGLPEAA GARDNLVRKK
1410 1420
KAANLNSIIH RLEKAASREE PIEWEF
Length:1,426
Mass (Da):156,408
Last modified:April 12, 2005 - v1
Checksum:i373175EE0CD6001F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090847 mRNA. Translation: AAH90847.1.
RefSeqiNP_001278162.1. NM_001291233.1.
NP_001278163.1. NM_001291234.1.
NP_001278167.1. NM_001291238.1.
NP_034116.3. NM_009986.4.
NP_941004.2. NM_198602.3.
UniGeneiMm.320317.
Mm.436792.

Genome annotation databases

GeneIDi13047.
KEGGimmu:13047.

Similar proteinsi

Entry informationi

Entry nameiQ5BL05_MOUSE
AccessioniPrimary (citable) accession number: Q5BL05
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: September 27, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)