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Protein
Submitted name:

MYH9 protein

Gene

MYH9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

Actin-bindingSAAS annotation, ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
MYH9 proteinImported
Submitted name:
Myosin-9Imported
Gene namesi
Name:MYH9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:7579. MYH9.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100345.

Expressioni

Gene expression databases

BgeeiENSG00000100345.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000216181.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini81 – 218Myosin motorInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation

Keywords - Domaini

Coiled coilSAAS annotation

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00760000118919.
HOGENOMiHOG000137603.
HOVERGENiHBG055056.

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR004009. Myosin_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF02736. Myosin_N. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BKV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQQAADKYL YVDKNFINNP LAQADWAAKK LVWVPSDKSG FEPASLKEEV
60 70 80 90 100
GEEAIVELVE NGKKVKVNKD DIQKMNPPKF SKVEDMAELT CLNEASVLHN
110 120 130 140 150
LKERYYSGLI YTYSGLFCVV INPYKNLPIY SEEIVEMYKG KKRHEMPPHI
160 170 180 190 200
YAITDTAYRS MMQDREDQSI LCTGESGAGK TENTKKVIQY LAYVASSHKS
210
KKDQEAYFKN RAVRLGVL
Length:218
Mass (Da):24,833
Last modified:April 12, 2005 - v1
Checksum:iFDEEE4681836CAAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393418 Genomic DNA. No translation available.
KF457437 Genomic DNA. No translation available.
KF457439 Genomic DNA. No translation available.
KF457440 Genomic DNA. No translation available.
KF511473 Genomic DNA. No translation available.
Z82215 Genomic DNA. No translation available.
BC090921 mRNA. Translation: AAH90921.1.
UniGeneiHs.474751.

Genome annotation databases

EnsembliENST00000401701; ENSP00000384631; ENSG00000100345.
UCSCiuc003api.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393418 Genomic DNA. No translation available.
KF457437 Genomic DNA. No translation available.
KF457439 Genomic DNA. No translation available.
KF457440 Genomic DNA. No translation available.
KF511473 Genomic DNA. No translation available.
Z82215 Genomic DNA. No translation available.
BC090921 mRNA. Translation: AAH90921.1.
UniGeneiHs.474751.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000216181.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000401701; ENSP00000384631; ENSG00000100345.
UCSCiuc003api.1. human.

Organism-specific databases

HGNCiHGNC:7579. MYH9.
OpenTargetsiENSG00000100345.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00760000118919.
HOGENOMiHOG000137603.
HOVERGENiHBG055056.

Miscellaneous databases

ChiTaRSiMYH9. human.

Gene expression databases

BgeeiENSG00000100345.

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR004009. Myosin_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF02736. Myosin_N. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5BKV1_HUMAN
AccessioniPrimary (citable) accession number: Q5BKV1
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: November 30, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.