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Protein
Submitted name:

Alcohol dehydrogenase 10A

Gene

adh1c

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Zn2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

ReactomeiR-XTR-2161541. Abacavir metabolism.
R-XTR-5365859. RA biosynthesis pathway.
R-XTR-71384. Ethanol oxidation.

Names & Taxonomyi

Protein namesi
Submitted name:
Alcohol dehydrogenase 10AImported
Submitted name:
MGC107857 proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:adh1cImported
Synonyms:ADH10AImported, MGC107857Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-6041030. adh1c.

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000060922.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 375357PKS_ERInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the zinc-containing alcohol dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0022. Eukaryota.
COG1062. LUCA.
GeneTreeiENSGT00430000030800.
HOGENOMiHOG000294674.
HOVERGENiHBG000195.
KOiK13951.
OrthoDBiEOG72NRQ6.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BKM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTAGKVIKC KAAVIWEKSA PFSIEEVEVA PPKANEVRIK IVATGICRSD
60 70 80 90 100
DHAIEGKLST VKFPVILGHE GVGIVESTGE SVKHIKPGDR VIPLFVPQCG
110 120 130 140 150
QCICCKDPRS NMCIAGKMKK AVGLMSDGTS RFTCKGKQIY HFMNTSTFTE
160 170 180 190 200
YTVAEEMSVA KIDSGASLDN TCLIGCGFST GYGSALNSAK VHPGSTCAIF
210 220 230 240 250
GLGGIGLAVI MGCKIAGAAR IIGVDINPDK FNIAKELGAT ECINPKDYDK
260 270 280 290 300
PVPQVILEQT GGGVDYAFEC VGHIETMLAA LNSSHFAYGT TVIVGVSAPD
310 320 330 340 350
STISFDPMIL LTGRTIKGSV FGGWKSKNSV PQLVSDSLAK KFDLEKLVTH
360 370
RLPLNKINEG FDLLRSGKSI RTILLV
Length:376
Mass (Da):39,963
Last modified:April 12, 2005 - v1
Checksum:iCDDD739A6A5E19A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01037222 Genomic DNA. No translation available.
BC091025 mRNA. Translation: AAH91025.1.
HF569244 Genomic DNA. Translation: CCP94568.1.
RefSeqiNP_001025581.1. NM_001030410.1.
UniGeneiStr.26581.

Genome annotation databases

EnsembliENSXETT00000024409; ENSXETP00000024409; ENSXETG00000011164.
GeneIDi594969.
KEGGixtr:594969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01037222 Genomic DNA. No translation available.
BC091025 mRNA. Translation: AAH91025.1.
HF569244 Genomic DNA. Translation: CCP94568.1.
RefSeqiNP_001025581.1. NM_001030410.1.
UniGeneiStr.26581.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000060922.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000024409; ENSXETP00000024409; ENSXETG00000011164.
GeneIDi594969.
KEGGixtr:594969.

Organism-specific databases

CTDi126.
XenbaseiXB-GENE-6041030. adh1c.

Phylogenomic databases

eggNOGiKOG0022. Eukaryota.
COG1062. LUCA.
GeneTreeiENSGT00430000030800.
HOGENOMiHOG000294674.
HOVERGENiHBG000195.
KOiK13951.
OrthoDBiEOG72NRQ6.

Enzyme and pathway databases

ReactomeiR-XTR-2161541. Abacavir metabolism.
R-XTR-5365859. RA biosynthesis pathway.
R-XTR-71384. Ethanol oxidation.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.180.10. 1 hit.
InterProiIPR013149. ADH_C.
IPR013154. ADH_N.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
IPR020843. PKS_ER.
[Graphical view]
PANTHERiPTHR11695. PTHR11695. 2 hits.
PfamiPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SMARTiSM00829. PKS_ER. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 2 hits.
SSF51735. SSF51735. 1 hit.
PROSITEiPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Whole bodyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "The Xenopus alcohol dehydrogenase gene family: characterization and comparative analysis incorporating amphibian and reptilian genomes."
    Borras E., Albalat R., Duester G., Pares X., Farres J.
    BMC Genomics 15:216-216(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ5BKM0_XENTR
AccessioniPrimary (citable) accession number: Q5BKM0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: June 8, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.