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Protein

ADP-ribosylation factor-like protein 11

Gene

Arl11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in apoptosis. May act as a tumor suppressor (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 248GTPBy similarity
Nucleotide bindingi61 – 655GTPBy similarity
Nucleotide bindingi120 – 1234GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 11
Gene namesi
Name:Arl11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1308083. Arl11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedSequence analysis
Chaini2 – 173172ADP-ribosylation factor-like protein 11PRO_0000207481Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineSequence analysis

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

PaxDbiQ5BK71.
PRIDEiQ5BK71.

PTM databases

iPTMnetiQ5BK71.
PhosphoSiteiQ5BK71.

Expressioni

Gene expression databases

BgeeiENSRNOG00000014653.
GenevisibleiQ5BK71. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019646.

Structurei

3D structure databases

ProteinModelPortaliQ5BK71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00840000129731.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ5BK71.
KOiK07959.
OMAiWKDYLEG.
OrthoDBiEOG091G0O0X.
PhylomeDBiQ5BK71.
TreeFamiTF105471.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5BK71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSVNSRGHK AQVVMLGLDC AGKTTILYKL KGNRLVDTLP TVGFNVEPLE
60 70 80 90 100
APGHVSLTLW DIGGQTQLRA TWKDYLEGID LLVYVLDSTD EARLPEAVAE
110 120 130 140 150
LEEVLEDPNM AGVPFLVLAN KQEAPDALPL LEIRNRLDLE RFQDHCWELR
160 170
ACSALTGQGL QEARQSLLHL LRS
Length:173
Mass (Da):19,156
Last modified:April 12, 2005 - v1
Checksum:i6B4F024821D39E83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091183 mRNA. Translation: AAH91183.1.
RefSeqiNP_001013451.1. NM_001013433.1.
XP_006252197.1. XM_006252135.2.
XP_008768988.1. XM_008770766.1.
UniGeneiRn.23090.

Genome annotation databases

EnsembliENSRNOT00000019646; ENSRNOP00000019646; ENSRNOG00000014653.
GeneIDi364396.
KEGGirno:364396.
UCSCiRGD:1308083. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091183 mRNA. Translation: AAH91183.1.
RefSeqiNP_001013451.1. NM_001013433.1.
XP_006252197.1. XM_006252135.2.
XP_008768988.1. XM_008770766.1.
UniGeneiRn.23090.

3D structure databases

ProteinModelPortaliQ5BK71.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019646.

PTM databases

iPTMnetiQ5BK71.
PhosphoSiteiQ5BK71.

Proteomic databases

PaxDbiQ5BK71.
PRIDEiQ5BK71.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000019646; ENSRNOP00000019646; ENSRNOG00000014653.
GeneIDi364396.
KEGGirno:364396.
UCSCiRGD:1308083. rat.

Organism-specific databases

CTDi115761.
RGDi1308083. Arl11.

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00840000129731.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ5BK71.
KOiK07959.
OMAiWKDYLEG.
OrthoDBiEOG091G0O0X.
PhylomeDBiQ5BK71.
TreeFamiTF105471.

Miscellaneous databases

PROiQ5BK71.

Gene expression databases

BgeeiENSRNOG00000014653.
GenevisibleiQ5BK71. RN.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
[Graphical view]
PfamiPF00025. Arf. 1 hit.
[Graphical view]
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51417. ARF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARL11_RAT
AccessioniPrimary (citable) accession number: Q5BK71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: April 12, 2005
Last modified: September 7, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.