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Protein

ADP-ribosylation factor-like protein 11

Gene

Arl11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May play a role in apoptosis. May act as a tumor suppressor (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi17 – 24GTPBy similarity8
Nucleotide bindingi61 – 65GTPBy similarity5
Nucleotide bindingi120 – 123GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 11
Gene namesi
Name:Arl11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1308083. Arl11.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedSequence analysis
ChainiPRO_00002074812 – 173ADP-ribosylation factor-like protein 11Add BLAST172

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineSequence analysis1

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

PaxDbiQ5BK71.
PRIDEiQ5BK71.

PTM databases

iPTMnetiQ5BK71.
PhosphoSitePlusiQ5BK71.

Expressioni

Gene expression databases

BgeeiENSRNOG00000014653.
GenevisibleiQ5BK71. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000019646.

Structurei

3D structure databases

ProteinModelPortaliQ5BK71.
SMRiQ5BK71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00890000139352.
HOGENOMiHOG000163691.
HOVERGENiHBG002073.
InParanoidiQ5BK71.
KOiK07959.
OMAiWKDYLEG.
OrthoDBiEOG091G0O0X.
PhylomeDBiQ5BK71.
TreeFamiTF105471.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51417. ARF. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5BK71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSVNSRGHK AQVVMLGLDC AGKTTILYKL KGNRLVDTLP TVGFNVEPLE
60 70 80 90 100
APGHVSLTLW DIGGQTQLRA TWKDYLEGID LLVYVLDSTD EARLPEAVAE
110 120 130 140 150
LEEVLEDPNM AGVPFLVLAN KQEAPDALPL LEIRNRLDLE RFQDHCWELR
160 170
ACSALTGQGL QEARQSLLHL LRS
Length:173
Mass (Da):19,156
Last modified:April 12, 2005 - v1
Checksum:i6B4F024821D39E83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091183 mRNA. Translation: AAH91183.1.
RefSeqiNP_001013451.1. NM_001013433.1.
XP_006252197.1. XM_006252135.3.
XP_017455251.1. XM_017599762.1.
UniGeneiRn.23090.

Genome annotation databases

EnsembliENSRNOT00000019646; ENSRNOP00000019646; ENSRNOG00000014653.
GeneIDi364396.
KEGGirno:364396.
UCSCiRGD:1308083. rat.

Similar proteinsi

Entry informationi

Entry nameiARL11_RAT
AccessioniPrimary (citable) accession number: Q5BK71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: April 12, 2005
Last modified: September 27, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families