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Protein

snRNA-activating protein complex subunit 3

Gene

Snapc3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiR-RNO-6807505. RNA polymerase II transcribes snRNA genes.
R-RNO-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.

Names & Taxonomyi

Protein namesi
Recommended name:
snRNA-activating protein complex subunit 3
Short name:
SNAPc subunit 3
Alternative name(s):
Small nuclear RNA-activating complex polypeptide 3
Gene namesi
Name:Snapc3
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1305172. Snapc3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000720271 – 407snRNA-activating protein complex subunit 3Add BLAST407

Proteomic databases

PaxDbiQ5BK68.
PRIDEiQ5BK68.

Expressioni

Gene expression databases

BgeeiENSRNOG00000010825.
GenevisibleiQ5BK68. RN.

Interactioni

Subunit structurei

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 (By similarity).By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015254.

Family & Domainsi

Sequence similaritiesi

Belongs to the SNAPC3/SRD2 family.Curated

Phylogenomic databases

eggNOGiKOG2664. Eukaryota.
ENOG411090A. LUCA.
GeneTreeiENSGT00390000005708.
HOGENOMiHOG000146435.
HOVERGENiHBG071400.
InParanoidiQ5BK68.
KOiK15210.
OMAiIFYPVIF.
OrthoDBiEOG091G0BC6.
PhylomeDBiQ5BK68.
TreeFamiTF317705.

Family and domain databases

InterProiIPR022042. snRNA-activating_su3.
[Graphical view]
PANTHERiPTHR13421. PTHR13421. 1 hit.
PfamiPF12251. zf-SNAP50_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BK68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEDPQGGGA GGPQHPVPSG SHSSFPEYEL PELHTRVFHV GAFGELWRGR
60 70 80 90 100
LGAQDLSLNE PQAAAQPTDG EASNNGFEDA AVAEDLGCSL EAAAELRVVC
110 120 130 140 150
GLDKLRCLGE DEDPEVIPEN TDLVTLCVRK GLLDYREENI TIDRACRQET
160 170 180 190 200
FAYEMESHAL GKKPENPADM IEEGESILSV NILYPVIFNK HREHKPYQTV
210 220 230 240 250
LVLGSQKLTE LRDSICCVSD LQIGGEFSNA PDQAPEHISK DLYKSAFFYF
260 270 280 290 300
EGTFYNDKRY PECRDLSRTI IEWSESHDRG YGKFQTARME DFTFNDLNIK
310 320 330 340 350
LGFPYLYCHQ GDCEHVVVIT DIRLVHHDDC LDRTLYPLLT KKHWLWTRKC
360 370 380 390 400
FVCKMYTARW VTNNDTFAPE DPCFFCDVCF RMLHYDSEGN KLGEFLAYPY

VDPGTFN
Length:407
Mass (Da):46,230
Last modified:April 12, 2005 - v1
Checksum:i6721A38C1D480A58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091186 mRNA. Translation: AAH91186.1.
RefSeqiNP_001013230.1. NM_001013212.1.
UniGeneiRn.204909.

Genome annotation databases

EnsembliENSRNOT00000015254; ENSRNOP00000015254; ENSRNOG00000010825.
GeneIDi362537.
KEGGirno:362537.
UCSCiRGD:1305172. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091186 mRNA. Translation: AAH91186.1.
RefSeqiNP_001013230.1. NM_001013212.1.
UniGeneiRn.204909.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015254.

Proteomic databases

PaxDbiQ5BK68.
PRIDEiQ5BK68.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000015254; ENSRNOP00000015254; ENSRNOG00000010825.
GeneIDi362537.
KEGGirno:362537.
UCSCiRGD:1305172. rat.

Organism-specific databases

CTDi6619.
RGDi1305172. Snapc3.

Phylogenomic databases

eggNOGiKOG2664. Eukaryota.
ENOG411090A. LUCA.
GeneTreeiENSGT00390000005708.
HOGENOMiHOG000146435.
HOVERGENiHBG071400.
InParanoidiQ5BK68.
KOiK15210.
OMAiIFYPVIF.
OrthoDBiEOG091G0BC6.
PhylomeDBiQ5BK68.
TreeFamiTF317705.

Enzyme and pathway databases

ReactomeiR-RNO-6807505. RNA polymerase II transcribes snRNA genes.
R-RNO-76071. RNA Polymerase III Transcription Initiation From Type 3 Promoter.

Miscellaneous databases

PROiQ5BK68.

Gene expression databases

BgeeiENSRNOG00000010825.
GenevisibleiQ5BK68. RN.

Family and domain databases

InterProiIPR022042. snRNA-activating_su3.
[Graphical view]
PANTHERiPTHR13421. PTHR13421. 1 hit.
PfamiPF12251. zf-SNAP50_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSNPC3_RAT
AccessioniPrimary (citable) accession number: Q5BK68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: April 12, 2005
Last modified: September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.