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Protein

TRAF-interacting protein with FHA domain-containing protein B

Gene

Tifab

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Inhibits TIFA-mediated TRAF6 activation possibly by inducing a conformational change in TIFA.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
TRAF-interacting protein with FHA domain-containing protein B
Alternative name(s):
TIFA-like protein
Gene namesi
Name:TifabBy similarity
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 17

Organism-specific databases

RGDi1311681 Tifab

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003206941 – 147TRAF-interacting protein with FHA domain-containing protein BAdd BLAST147

Proteomic databases

PaxDbiQ5BK67
PRIDEiQ5BK67

Expressioni

Gene expression databases

BgeeiENSRNOG00000011947
GenevisibleiQ5BK67 RN

Interactioni

Subunit structurei

Interacts with TIFA.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000015878

Structurei

3D structure databases

ProteinModelPortaliQ5BK67
SMRiQ5BK67
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 108FHASequence analysisAdd BLAST73

Phylogenomic databases

eggNOGiENOG410IYRT Eukaryota
ENOG410YZ4Y LUCA
GeneTreeiENSGT00510000049624
HOGENOMiHOG000154576
HOVERGENiHBG095665
InParanoidiQ5BK67
OMAiCVWVNGL
OrthoDBiEOG091G0KR0
PhylomeDBiQ5BK67
TreeFamiTF333218

Family and domain databases

CDDicd00060 FHA, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR008984 SMAD_FHA_dom_sf
IPR033621 TIFA
PANTHERiPTHR31266 PTHR31266, 1 hit
PfamiView protein in Pfam
PF00498 FHA, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit

Sequencei

Sequence statusi: Complete.

Q5BK67-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERPLTVLQV SLYHPTQGPV AFAKVPLQLQ HDASRLLVGR GQDTHLQLQL
60 70 80 90 100
PQLSRHHLCL EPYLEKGSNL LAFCLKVLTR QSCVWVNGLP LRYLEQVPLH
110 120 130 140
SVNRISFSGI QMLIRKEGGA SLEAFVCYFH LSPSPLIYRP KAQETDE
Length:147
Mass (Da):16,666
Last modified:April 12, 2005 - v1
Checksum:iF8B4BBB3A2ED832A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091188 mRNA Translation: AAH91188.1
RefSeqiNP_001020200.1, NM_001025029.1
XP_006253640.1, XM_006253578.3
XP_006253641.1, XM_006253579.3
XP_008769665.1, XM_008771443.2
UniGeneiRn.160910

Genome annotation databases

EnsembliENSRNOT00000015878; ENSRNOP00000015878; ENSRNOG00000011947
GeneIDi364674
KEGGirno:364674
UCSCiRGD:1311681 rat

Similar proteinsi

Entry informationi

Entry nameiTIFAB_RAT
AccessioniPrimary (citable) accession number: Q5BK67
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: April 12, 2005
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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