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Protein

Protein Mpv17

Gene

Mpv17

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance (By similarity).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Mpv17
Gene namesi
Name:Mpv17
Synonyms:Mpv17l
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1310512. Mpv17.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei18 – 3821HelicalSequence analysisAdd
BLAST
Transmembranei57 – 7721HelicalSequence analysisAdd
BLAST
Transmembranei94 – 11421HelicalSequence analysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Protein Mpv17PRO_0000234399Add
BLAST

Proteomic databases

PaxDbiQ5BK62.
PRIDEiQ5BK62.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000037647.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1944. Eukaryota.
ENOG4111SYH. LUCA.
HOGENOMiHOG000039675.
HOVERGENiHBG105417.
InParanoidiQ5BK62.
KOiK13348.

Family and domain databases

InterProiIPR007248. Mpv17_PMP22.
[Graphical view]
PANTHERiPTHR11266. PTHR11266. 1 hit.
PfamiPF04117. Mpv17_PMP22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BK62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALWRAYQRA LAAHPWKVQV LTAGSLMGLG DIISQQLVER RGLQQHQTGR
60 70 80 90 100
TLTMASLGCG FVGPVVGGWY RVLDHLIPGT TKVNALKKML LDQGGFAPCF
110 120 130 140 150
LGCFLPLVGV LNGMSAQDNW AKLKRDYPDA LITNYYLWPA VQLANFYLVP
160 170
LHYRLAVVQC VAVVWNSYLS WKAHQL
Length:176
Mass (Da):19,627
Last modified:April 12, 2005 - v1
Checksum:i1284B5DBC06D68FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091193 mRNA. Translation: AAH91193.1.
RefSeqiNP_001091710.1. NM_001098240.1.
UniGeneiRn.207192.

Genome annotation databases

GeneIDi360463.
KEGGirno:360463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC091193 mRNA. Translation: AAH91193.1.
RefSeqiNP_001091710.1. NM_001098240.1.
UniGeneiRn.207192.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000037647.

Proteomic databases

PaxDbiQ5BK62.
PRIDEiQ5BK62.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi360463.
KEGGirno:360463.

Organism-specific databases

CTDi255027.
RGDi1310512. Mpv17.

Phylogenomic databases

eggNOGiKOG1944. Eukaryota.
ENOG4111SYH. LUCA.
HOGENOMiHOG000039675.
HOVERGENiHBG105417.
InParanoidiQ5BK62.
KOiK13348.

Miscellaneous databases

PROiQ5BK62.

Family and domain databases

InterProiIPR007248. Mpv17_PMP22.
[Graphical view]
PANTHERiPTHR11266. PTHR11266. 1 hit.
PfamiPF04117. Mpv17_PMP22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.

Entry informationi

Entry nameiMPV17_RAT
AccessioniPrimary (citable) accession number: Q5BK62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: April 12, 2005
Last modified: June 8, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.