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Protein

Glutathione S-transferase

Gene

Gstm4

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Enzyme and pathway databases

ReactomeiR-RNO-156590. Glutathione conjugation.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferaseUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:Gstm4Imported
Synonyms:MGC108896Imported
ORF Names:rCG_29014Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1565825. Gstm4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSRNOG00000019221.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025994.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 88GST N-terminalInterPro annotationAdd BLAST88
Domaini90 – 208GST C-terminalInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the GST superfamily. Mu family.UniRule annotation
Contains 1 GST C-terminal domain.UniRule annotation
Contains 1 GST N-terminal domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IN5J. Eukaryota.
ENOG4110YU0. LUCA.
GeneTreeiENSGT00550000074559.
HOGENOMiHOG000115735.
HOVERGENiHBG106842.
KOiK00799.
OMAiAQPIRYL.
OrthoDBiEOG091G0K2E.
TreeFamiTF353040.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5BK56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMTLGYWDI RGLAHAIRLL LEYTDSSYEE KRYTMGDAPD YDRSQWLSEK
60 70 80 90 100
FKLGLDFPNL PYLIDGSHKI TQSNAILRYI ARKHNLCGET EEEKIRVDIL
110 120 130 140 150
ENQAMDVSNQ LARVCYSPDF ENLKAEYLEQ LPGMMELFSQ FLGKQTWFVG
160 170 180 190 200
EKITFVDFLA YDILDLHLIF EPKCLDAFPN LKDFVARFEG LKKISVYMKT
210
SRFLRTPLYT RVATWGNK
Length:218
Mass (Da):25,553
Last modified:April 12, 2005 - v1
Checksum:iAAB172206BDDE0F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097845 Genomic DNA. No translation available.
BC091199 mRNA. Translation: AAH91199.1.
CH473952 Genomic DNA. Translation: EDL81910.1.
RefSeqiNP_001019475.1. NM_001024304.1.
UniGeneiRn.198607.

Genome annotation databases

EnsembliENSRNOT00000025994; ENSRNOP00000025994; ENSRNOG00000019221.
GeneIDi499689.
KEGGirno:499689.
UCSCiRGD:1565825. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097845 Genomic DNA. No translation available.
BC091199 mRNA. Translation: AAH91199.1.
CH473952 Genomic DNA. Translation: EDL81910.1.
RefSeqiNP_001019475.1. NM_001024304.1.
UniGeneiRn.198607.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025994.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000025994; ENSRNOP00000025994; ENSRNOG00000019221.
GeneIDi499689.
KEGGirno:499689.
UCSCiRGD:1565825. rat.

Organism-specific databases

CTDi2948.
RGDi1565825. Gstm4.

Phylogenomic databases

eggNOGiENOG410IN5J. Eukaryota.
ENOG4110YU0. LUCA.
GeneTreeiENSGT00550000074559.
HOGENOMiHOG000115735.
HOVERGENiHBG106842.
KOiK00799.
OMAiAQPIRYL.
OrthoDBiEOG091G0K2E.
TreeFamiTF353040.

Enzyme and pathway databases

ReactomeiR-RNO-156590. Glutathione conjugation.

Gene expression databases

BgeeiENSRNOG00000019221.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR003081. GST_mu.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
PRINTSiPR01267. GSTRNSFRASEM.
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5BK56_RAT
AccessioniPrimary (citable) accession number: Q5BK56
Entry historyi
Integrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: November 30, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.