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Reviewed, UniProtKB/Swiss-Prot Q5BJY6 (NAGA_RAT)

Last modified November 3, 2009. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase
    Amidohydrolase domain-containing protein 2
Gene names
Name: Amdhd2
OrganismRattus norvegicus (Rat)
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.

Sequence similarities

Belongs to the nagA family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological processN-acetylglucosamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionN-acetylglucosamine-6-phosphate deacetylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 409409Putative N-acetylglucosamine-6-phosphate deacetylase
PRO_0000315778

Sequences

Sequence LengthMass (Da)Tools
Q5BJY6-1 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: F2AF4B70CE1484BC

FASTA40943,539
        10         20         30         40         50         60 
MRSGQSAALA PVLQFTNCRI LRGGTLLRED LWVRGGRILD PEKLFFEERR VADEQRDCGG 

        70         80         90        100        110        120 
RILAPGFIDV QINGGFGVDF SRATEDVGSG VALVARRLLS HGVTSFCPTL VTSPPEVYHK 

       130        140        150        160        170        180 
VLPQIPVKSG GPHGAGVLGV HLEGPFISRE KRGAHPEAYL RSFGANAFHD VLATYGPLDN 

       190        200        210        220        230        240 
VCIVTLAPEL DRSHEVIQAL TAKGIRVSLG HSVADLRAAE VAVQSGATFI THLFNAMLPF 

       250        260        270        280        290        300 
HHRDPGIVGL LTSDQLPPGH CIFYGMIADG IHTNPAALRI AHRAHPQGLV LVTDAVPALG 

       310        320        330        340        350        360 
LGNGRHTLGQ QEVEVDGLIA YIAGTKTLSG SIAPMDVCIR HFLQATGCSV ESALEAASLH 

       370        380        390        400 
PAQLLGLEKT KGSLDFGADA DFVVLDDTLH VQATYISGEL VWQAEEAGL 

« Hide

References

[1]"Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M. expand/collapse author list , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
Nature 428:493-521(2004) [PubMed: 15057822] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Brown Norway.
+Additional computationally mapped references.

Cross-references

Sequence databases

AABR03073424 Genomic DNA. No translation available.
IPIIPI00368721.
RefSeqNP_001020161.2.
UniGeneRn.163127

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ5BJY6.

Genome annotation databases

EnsemblENSRNOT00000008537; ENSRNOP00000008537; ENSRNOG00000006460; Rattus norvegicus. [Genome view]
GeneID302972.
KEGGrno:302972.
UCSCNM_001024990. rat.

Organism-specific databases

CTD302972.
RGD1304601. Amdhd2.

Phylogenomic databases

HOVERGENQ5BJY6.
OMAQGLHAYV.

Enzyme and pathway databases

BRENDA3.5.1.25. 248.

Gene expression databases

GenevestigatorQ5BJY6.

Family and domain databases

InterProIPR006680. Amidohydro_1.
IPR003764. GlcNAc_6-P_deAcase.
[Graphical view]
PfamPF01979. Amidohydro_1. 2 hits.
[Graphical view]
TIGRFAMsTIGR00221. nagA. 1 hit.
ProtoNetSearch...

Other Resources

NextBio650430.

Entry information

Entry nameNAGA_RAT
AccessionPrimary (citable) accession number: Q5BJY6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: November 3, 2009
This is version 38 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents