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Q5BJY3 (IN80C_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
INO80 complex subunit C
Gene names
Name:Ino80c
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Subunit structure

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10 By similarity.

Subcellular location

Nucleus By similarity.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 191191INO80 complex subunit C
PRO_0000079319

Amino acid modifications

Cross-link21Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) By similarity
Cross-link22Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) By similarity
Cross-link40Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5BJY3 [UniParc].

Last modified April 12, 2005. Version 1.
Checksum: 09AD29E0A914A73B

FASTA19120,424
        10         20         30         40         50         60 
MAAQIPIVAA TSTPTVARNS KKRPASPSHN SSGGGYGASK KKKLSASGFA QGVSIEAMSE 

        70         80         90        100        110        120 
SKMASSELSS GPVEKAAKPL PFKDPNFVHS GHGGAVAGKK NRTWKNLKQI LAAERALPWQ 

       130        140        150        160        170        180 
LNDPNYFSID APPSFKPAKK YSDVSGLLAN YTDPQSKLRF STVEEFSYIR RLPSDVVTGY 

       190 
LTLRKATSIV P 

« Hide

References

[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Heart.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC091281 mRNA. Translation: AAH91281.1.
RefSeqNP_001017446.1. NM_001017446.1.
UniGeneRn.18319.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10116.ENSRNOP00000022169.

PTM databases

PhosphoSiteQ5BJY3.

Proteomic databases

PaxDbQ5BJY3.
PRIDEQ5BJY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000022169; ENSRNOP00000022169; ENSRNOG00000016532.
GeneID291737.
KEGGrno:291737.
UCSCRGD:1310199. rat.

Organism-specific databases

CTD125476.
RGD1310199. Ino80c.

Phylogenomic databases

eggNOGCOG5195.
GeneTreeENSGT00390000014303.
HOGENOMHOG000039089.
HOVERGENHBG103414.
InParanoidQ5BJY3.
KOK11667.
OMAKMASSEL.
OrthoDBEOG786H5F.
PhylomeDBQ5BJY3.
TreeFamTF323529.

Gene expression databases

GenevestigatorQ5BJY3.

Family and domain databases

InterProIPR013272. YL1_C.
[Graphical view]
PfamPF08265. YL1_C. 1 hit.
[Graphical view]
SMARTSM00993. YL1_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio633084.
PROQ5BJY3.

Entry information

Entry nameIN80C_RAT
AccessionPrimary (citable) accession number: Q5BJY3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: April 12, 2005
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program