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Q5BJS8

- Q5BJS8_RAT

UniProt

Q5BJS8 - Q5BJS8_RAT

Protein
Submitted name:

Itpr1 protein

Gene

Itpr1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. intracellular ligand-gated calcium channel activity Source: Ensembl
    2. phosphatidylinositol binding Source: Ensembl

    GO - Biological processi

    1. endoplasmic reticulum calcium ion homeostasis Source: Ensembl
    2. intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress Source: Ensembl
    3. post-embryonic development Source: Ensembl
    4. release of sequestered calcium ion into cytosol Source: Ensembl
    5. response to hypoxia Source: Ensembl
    6. voluntary musculoskeletal movement Source: Ensembl

    Enzyme and pathway databases

    ReactomeiREACT_211910. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Itpr1 proteinImported
    Gene namesi
    Name:Itpr1Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi2933. Itpr1.

    Subcellular locationi

    GO - Cellular componenti

    1. calcineurin complex Source: Ensembl
    2. endoplasmic reticulum membrane Source: Ensembl
    3. nuclear inner membrane Source: Ensembl
    4. nucleolus Source: Ensembl
    5. platelet dense granule membrane Source: Ensembl
    6. platelet dense tubular network Source: Ensembl
    7. postsynaptic density Source: Ensembl
    8. sarcoplasmic reticulum Source: Ensembl

    Expressioni

    Gene expression databases

    GenevestigatoriQ5BJS8.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000007660.
    InParanoidiQ5BJS8.
    KOiK04958.

    Family and domain databases

    InterProiIPR015925. Ryanodine_recept-rel.
    [Graphical view]
    PANTHERiPTHR13715. PTHR13715. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q5BJS8-1 [UniParc]FASTAAdd to Basket

    « Hide

    FEEHIKEEHN MWHYLCFIVL VKVKDSTEYT GPESYVAEMI RERNLDWFPR    50
    MRAMSLVSSD SEGEQNELRN LQEKLESTMK LVTNLSGQLS ELKDQMTEQR 100
    KQKQRIGLLG HPPHMNVNPQ QPA 123
    Length:123
    Mass (Da):14,484
    Last modified:April 12, 2005 - v1
    Checksum:i50C33E512B23DC62
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC091346 mRNA. Translation: AAH91346.1.
    RefSeqiNP_001007236.2. NM_001007235.2.
    NP_001257525.1. NM_001270596.1.
    NP_001257526.1. NM_001270597.1.
    UniGeneiRn.2135.

    Genome annotation databases

    GeneIDi25262.
    KEGGirno:25262.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC091346 mRNA. Translation: AAH91346.1 .
    RefSeqi NP_001007236.2. NM_001007235.2.
    NP_001257525.1. NM_001270596.1.
    NP_001257526.1. NM_001270597.1.
    UniGenei Rn.2135.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 25262.
    KEGGi rno:25262.

    Organism-specific databases

    CTDi 3708.
    RGDi 2933. Itpr1.

    Phylogenomic databases

    HOGENOMi HOG000007660.
    InParanoidi Q5BJS8.
    KOi K04958.

    Enzyme and pathway databases

    Reactomei REACT_211910. Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

    Gene expression databases

    Genevestigatori Q5BJS8.

    Family and domain databases

    InterProi IPR015925. Ryanodine_recept-rel.
    [Graphical view ]
    PANTHERi PTHR13715. PTHR13715. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ5BJS8_RAT
    AccessioniPrimary (citable) accession number: Q5BJS8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 12, 2005
    Last sequence update: April 12, 2005
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)