Q5BJI6 (POP5_DANRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P/MRP protein subunit POP5
EC=3.1.26.5

Gene names

Name:	pop5
ORF Names:	zgc:110616

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Subcellular location	Nucleus › nucleolus By similarity.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Nucleus
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ribonuclease P/MRP protein subunit POP5		PRO_0000239009

Sequences

	Sequence		Length	Mass (Da)
	Q5BJI6 [UniParc]. Last modified April 12, 2005. Version 1. Checksum: E0C78539E13B9880	FASTA	169	19,306
	10 20 30 40 50 60 MVRFKSRYLL CELCVSEPSS LHLFEDKVVY QALRGAVNRA HGDYGAAIFN ITLGVLVKYL 70 80 90 100 110 120 NAHTGVVLIR CRKAHYRLVW SSLPFITFLE NRGQKVRCFF NCIHVGGTIR TSQKFLIKYN 130 140 150 160 RQQLQRMLLD CKTDAEKQDV RKAILSCSLN LIKGEETDGS DDDGDEEDT

References

[1]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Embryo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC091467 mRNA. Translation: AAH91467.1.
IPI	IPI00555358.
RefSeq	NP_001013566.1. NM_001013548.1.
UniGene	Dr.39115.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000075491; ENSDARP00000069973; ENSDARG00000053452.
GeneID	541421.
KEGG	dre:541421.
Organism-specific databases
CTD	51367.
ZFIN	ZDB-GENE-050320-123. pop5.
Phylogenomic databases
eggNOG	NOG284693.
GeneTree	ENSGT00390000012331.
HOGENOM	HOG000293345.
HOVERGEN	HBG082157.
InParanoid	Q5BJI6.
KO	K03537.
OMA	CEVVSDD.
OrthoDB	EOG49W2GX.
Gene expression databases
ArrayExpress	Q5BJI6.
Bgee	Q5BJI6.
Family and domain databases
InterPro	IPR016819. RNase_P/MRP_POP5. IPR002759. RNase_P/MRP_subunit. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF023803. Ribonuclease_P_prd. 1 hit.
ProtoNet	Search...
Other
NextBio	20879231.

Entry information

Entry name

POP5_DANRE

Accession

Primary (citable) accession number: Q5BJI6

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	April 12, 2005
Last modified:	April 3, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program