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Protein
Submitted name:

PSAP protein

Gene

PSAP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
PSAP proteinImported
Submitted name:
ProsaposinImported
Gene namesi
Name:PSAPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000197746.13.
HGNCiHGNC:9498. PSAP.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197746.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_501109954917 – 240Sequence analysisAdd BLAST224

Proteomic databases

MaxQBiQ5BJH1.

Expressioni

Gene expression databases

BgeeiENSG00000197746.

Interactioni

Protein-protein interaction databases

IntActiQ5BJH1. 2 interactors.

Structurei

3D structure databases

SMRiQ5BJH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 58Saposin A-typeInterPro annotationAdd BLAST41
Domaini61 – 108Saposin B-typeInterPro annotationAdd BLAST48
Domaini121 – 202Saposin B-typeInterPro annotationAdd BLAST82
Domaini204 – 240Saposin A-typeInterPro annotationAdd BLAST37

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000063434.
HOGENOMiHOG000049216.
HOVERGENiHBG002617.

Family and domain databases

Gene3Di1.10.225.10. 2 hits.
InterProiView protein in InterPro
IPR003119. SAP_A.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR008373. Saposin.
IPR011001. Saposin-like.
IPR008139. SaposinB_dom.
PfamiView protein in Pfam
PF02199. SapA. 2 hits.
PF05184. SapB_1. 2 hits.
PF03489. SapB_2. 1 hit.
PRINTSiPR01797. SAPOSIN.
SMARTiView protein in SMART
SM00162. SAPA. 2 hits.
SM00741. SapB. 2 hits.
SUPFAMiSSF47862. SSF47862. 2 hits.
PROSITEiView protein in PROSITE
PS51110. SAP_A. 2 hits.
PS50015. SAP_B. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5BJH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYALFLLASL LGAALAGPVL GLKECTRGSA VWCQNVKTAS DCGAVKHCLQ
60 70 80 90 100
TVWNKPTVKS LPCDICKDVV TAAGDMLKDN ATEEEILVYL EVSPELVCSM
110 120 130 140 150
LHLCSGTRLP ALTVHVTQPK DGGFCEVCKK LVGYLDRNLE KNSTKQEILA
160 170 180 190 200
ALEKGCSFLP DPYQKQCDQF VAEYEPVLIE ILVEVMDPSF VCLKIGACPS
210 220 230 240
AHKPLLGTEK CIWGPSYWCQ NTETAAQCNA VEHCKRHVWN
Length:240
Mass (Da):26,309
Last modified:April 12, 2005 - v1
Checksum:i19E645E7952E5AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073370 Genomic DNA. No translation available.
AL731541 Genomic DNA. No translation available.
BC091483 mRNA. Translation: AAH91483.1.
UniGeneiHs.523004.

Genome annotation databases

EnsembliENST00000610929; ENSP00000480857; ENSG00000197746.
UCSCiuc057twu.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5BJH1_HUMAN
AccessioniPrimary (citable) accession number: Q5BJH1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 12, 2005
Last sequence update: April 12, 2005
Last modified: November 22, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported