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Q5BIY5 (RN145_XENLA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
RING finger protein 145
Gene names
Name:rnf145
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length695 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Contains 1 RING-type zinc finger.

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
Zinc-finger
   LigandMetal-binding
Zinc
Gene Ontology (GO)
   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 695695RING finger protein 145
PRO_0000294027

Regions

Transmembrane53 – 7321Helical; Potential
Transmembrane77 – 9721Helical; Potential
Transmembrane123 – 14321Helical; Potential
Transmembrane146 – 16621Helical; Potential
Transmembrane168 – 18821Helical; Potential
Transmembrane225 – 24521Helical; Potential
Transmembrane275 – 29521Helical; Potential
Transmembrane316 – 33621Helical; Potential
Transmembrane340 – 36021Helical; Potential
Transmembrane384 – 40421Helical; Potential
Transmembrane410 – 43021Helical; Potential
Transmembrane460 – 48021Helical; Potential
Transmembrane482 – 50221Helical; Potential
Zinc finger537 – 57539RING-type; atypical

Sequences

Sequence LengthMass (Da)Tools
Q5BIY5 [UniParc].

Last modified April 12, 2005. Version 1.
Checksum: FD9A5F6DFAFEFB66

FASTA69578,494
        10         20         30         40         50         60 
MGAKEKLEAM LNVALRVPSI MLLDVLYRWD VSSFFQQIQR SSLNKNPLFQ YKYLALNMHY 

        70         80         90        100        110        120 
VGYILSVVLL TLPRQHLAKL YLYFVAALLL FAGHQISRDY VRSELESGYE GPMHLEPLSM 

       130        140        150        160        170        180 
NRFITALVGQ LVVCTLCSCV MKTKQIWLFS AHMLPLLARL CLIPIETIVV INKFAMIFTG 

       190        200        210        220        230        240 
LEVLYFLASN LLVPFNLAKS AYRELAQVVE VYGLLALGMS LWNQLVVPVL FMVFWLVLFA 

       250        260        270        280        290        300 
LQIYTYFSTR DQPTSRERLL FLFLTSIAEC CSTPYSLLGL VFTVSFVALG VLTLCKFYLQ 

       310        320        330        340        350        360 
GYRAFMNDPA MNRGMTEGVT LLILAVQTGL IELQVVHRAF LLSIILFIVV ASILQSMLEI 

       370        380        390        400        410        420 
ADPIVLALGA SRDKSLWKHF RAVSLCLFLL VFPSYMAYMI CQFFHMDFWL LIIISSSILT 

       430        440        450        460        470        480 
SLQVLGTLFV YVLFMIEEFR KEPVENVDDA IYYVNGTYRL LEFLVALCVV AYGVSETVFG 

       490        500        510        520        530        540 
EWTVMGSMII FIHSYYNVWL RAQLGWKSFL LRRDAVNKIK SLPVSTKEQL EQHNDICSIC 

       550        560        570        580        590        600 
YQDMNSAVIT PCSHFFHPGC LKKWLYVQET CPLCHCQLKS LSQQAVAESG SSTNPVVEQS 

       610        620        630        640        650        660 
ANNPPQEPLS AVAATTETLG TVPTCSALEQ EPTMDIEPAE SLVERRGELE VHVSQEEANS 

       670        680        690 
NSNEVLQRIL TTGKVQPEDL NVKALPPESE VCAGI

« Hide

References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Egg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BC091708 mRNA. Translation: AAH91708.1.
RefSeqNP_001089304.1. NM_001095835.1.
UniGeneXl.7514.

3D structure databases

ProteinModelPortalQ5BIY5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID734353.
KEGGxla:734353.

Organism-specific databases

CTD153830.

Phylogenomic databases

HOVERGENHBG054921.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
InterProIPR025754. TRC8_N_dom.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamPF13705. TRC8_N. 1 hit.
PF13639. zf-RING_2. 1 hit.
[Graphical view]
SMARTSM00184. RING. 1 hit.
[Graphical view]
PROSITEPS00518. ZF_RING_1. False negative.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRN145_XENLA
AccessionPrimary (citable) accession number: Q5BIY5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: April 12, 2005
Last modified: April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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