ID   Q5BDD5_EMENI            Unreviewed;       394 AA.
AC   Q5BDD5; C8VM60;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   RecName: Full=protein-histidine N-methyltransferase {ECO:0000256|ARBA:ARBA00012533};
DE            EC=2.1.1.85 {ECO:0000256|ARBA:ARBA00012533};
GN   ORFNames=ANIA_01445 {ECO:0000313|EMBL:CBF84871.1};
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS   M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Nidulantes.
OX   NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF84871.1, ECO:0000313|Proteomes:UP000000560};
RN   [1] {ECO:0000313|Proteomes:UP000000560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R., Batzoglou S.,
RA   Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA   Jurka J., Scazzocchio C., Farman M., Butler J., Purcell S., Harris S.,
RA   Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA   Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA   Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA   Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA   Denning D.W., Caddick M., Hynes M., Paoletti M., Fischer R., Miller B.,
RA   Dyer P., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2] {ECO:0000313|Proteomes:UP000000560}
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA   Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA   Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA   Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA   Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA   Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA   van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA   Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA   Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA   Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA   Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA   Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA   van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA   Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA   Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT   effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. METTL18
CC       family. {ECO:0000256|ARBA:ARBA00038126}.
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DR   EMBL; BN001307; CBF84871.1; -; Genomic_DNA.
DR   RefSeq; XP_659049.1; XM_653957.1.
DR   AlphaFoldDB; Q5BDD5; -.
DR   STRING; 227321.Q5BDD5; -.
DR   EnsemblFungi; CBF84871; CBF84871; ANIA_01445.
DR   GeneID; 2875484; -.
DR   KEGG; ani:AN1445.2; -.
DR   VEuPathDB; FungiDB:AN1445; -.
DR   eggNOG; KOG2920; Eukaryota.
DR   HOGENOM; CLU_038704_1_0_1; -.
DR   InParanoid; Q5BDD5; -.
DR   OMA; NLLLTWH; -.
DR   OrthoDB; 276605at2759; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018064; F:protein-L-histidine N-tele-methyltransferase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR019410; Methyltransf_16.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR   PANTHER; PTHR14614:SF39; HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000560}.
SQ   SEQUENCE   394 AA;  42456 MW;  5659B10CAFE4B894 CRC64;
     MASKFSFGFS GDDIDIDLDE NELDDATESG HQDAGTASTL PELVKAQKHE IDEWLSMLPS
     QISYNTCTIS PFQEKGLGQG ASASTDIGAN TVTVARRDVF DIRAQLMVED SAEEQNGELI
     AGLEKGDITP NFYEGGFKTW ECSIDLAGLV VGEGVGLEDE GEDRHVIELG SGTAVPSLAV
     FAQLLARTET DGTTSKPAEK KKQTHFTFAD YNSAVLRLVT VPNLLLTWNH FTTHRKSAQP
     SDGQSEDKAE SQEEMLDITP DLVERFQSDL AHRGITVSFI SGAWSPSFVE LVFSSPELAG
     YRTLILASET IYSPASLAAF SETLLMLLRR SSQSNHASRA LVAAKKVYFG VGGGVDEFLT
     ILRSVADGNV DVGERMDVKS AGVGRTILEV SAST
//