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Q5BB53

- BGLI_EMENI

UniProt

Q5BB53 - BGLI_EMENI

Protein

Probable beta-glucosidase I

Gene

bglI

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 2 (15 Jun 2010)
      Previous versions | rss
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    Functioni

    Beta-glucosidases are one of a number of cellulolytic enzymes, and catalyze the last step releasing glucose from the inhibitory cellobiose.By similarity

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei225 – 2251By similarity

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    UniPathwayiUPA00696.

    Protein family/group databases

    CAZyiGH3. Glycoside Hydrolase Family 3.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable beta-glucosidase I (EC:3.2.1.21)
    Alternative name(s):
    Beta-D-glucoside glucohydrolase I
    Cellobiase I
    Gentiobiase I
    Gene namesi
    Name:bglI
    ORF Names:AN2227
    OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
    Taxonomic identifieri227321 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000000560: Chromosome VII

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 839839Probable beta-glucosidase IPRO_0000394890Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi197 – 1971N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi494 – 4941N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi162425.CADANIAP00008912.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5BB53.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini399 – 522124PA14Add
    BLAST

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 3 family.Curated
    Contains 1 PA14 domain.Curated

    Phylogenomic databases

    eggNOGiCOG1472.
    HOGENOMiHOG000031215.
    KOiK05349.
    OrthoDBiEOG7H799Q.

    Family and domain databases

    Gene3Di3.20.20.300. 1 hit.
    3.40.50.1700. 2 hits.
    InterProiIPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR019800. Glyco_hydro_3_AS.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    IPR011658. PA14.
    [Graphical view]
    PANTHERiPTHR30620. PTHR30620. 1 hit.
    PfamiPF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    PF07691. PA14. 1 hit.
    [Graphical view]
    PRINTSiPR00133. GLHYDRLASE3.
    SMARTiSM00758. PA14. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 2 hits.
    PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5BB53-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPQLDVDKTI EELRLGEKID LVSGIDFWHT ASVPRLNIPS LRMSDGPNGV    50
    RGTRFFNGVP AACFPCATAL GATWDTELLH KVGHLMGEEA IAKGAHVILG 100
    PTINTQRSPL GGRGFESFAE DGVLAGHLAG YCSKGIQEKG VAACLKHFVC 150
    NDQEHERLAV DSIVTDRATR EIYLLPFQIA MRICKTATVM TAYNKINGTH 200
    VSENKKYITD ILRKEWGWDG LVMSDWFGTY SCTSESIIAG LDIEMPGKTR 250
    WRGDALAHAV SSNKVHEFVL DERVRNVLNL VNYVEPLGIP ENAEEKVLNR 300
    PEDQALLRRA AAESIVLLKN EDNILPFNKE KSIAVIGPNA KIAAYCGGGS 350
    ASLDAYYTIT PFEGVSAQSK GEVHFAQGSY SYKDLPLIGH LLKTDDGKTG 400
    FKFRVYDEPA SSSNRELLHE LHLVSSQGFL MDYRHPKIKS YLYYVDMEGY 450
    FTPEESGVYD FGVVVVGTGK LLVDDEVVVD NTKNQRLGSA FFGNGTVEEK 500
    GSKELMAGQK YKITFQFGTA PTSDIDTRGV VIFGPGGFRF GAARRQTQEE 550
    LISKAVEVAS KADQVVVFAG LTSEWETEGY DRPDMDLPPG SDELISKILE 600
    VKPNAAIVIQ SGTPVTMPWA PKAKALLQAW FGGNECGNGI ADVLYGNVNP 650
    SGKLPLTFPV RLQDNPSYLN FRSERGRVLY GEDIYVGYRY YEKAQLPPLF 700
    PFGHGLSYTT FTREKLELNT SPEKDKLQDG EPITARVTVT NTGKVAGAET 750
    VQLWVVPPPT EVNRPVRELK GFAKVHLEPG ESKDVEIVVE KKLATSWWDE 800
    KREAWASEKG VYWVQVTGTG EGVLTAEFEV KKTRFWTGL 839
    Length:839
    Mass (Da):92,621
    Last modified:June 15, 2010 - v2
    Checksum:i8790901E0381A819
    GO

    Sequence cautioni

    The sequence CBF86422.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence EAA63912.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ490477 mRNA. Translation: ABF50853.1.
    AACD01000036 Genomic DNA. Translation: EAA63912.1. Sequence problems.
    BN001307 Genomic DNA. Translation: CBF86422.1. Sequence problems.
    RefSeqiXP_659831.1. XM_654739.1.

    Genome annotation databases

    EnsemblFungiiCADANIAT00008912; CADANIAP00008912; CADANIAG00008912.
    GeneIDi2875705.
    KEGGiani:AN2227.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ490477 mRNA. Translation: ABF50853.1 .
    AACD01000036 Genomic DNA. Translation: EAA63912.1 . Sequence problems.
    BN001307 Genomic DNA. Translation: CBF86422.1 . Sequence problems.
    RefSeqi XP_659831.1. XM_654739.1.

    3D structure databases

    ProteinModelPortali Q5BB53.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 162425.CADANIAP00008912.

    Protein family/group databases

    CAZyi GH3. Glycoside Hydrolase Family 3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANIAT00008912 ; CADANIAP00008912 ; CADANIAG00008912 .
    GeneIDi 2875705.
    KEGGi ani:AN2227.2.

    Phylogenomic databases

    eggNOGi COG1472.
    HOGENOMi HOG000031215.
    KOi K05349.
    OrthoDBi EOG7H799Q.

    Enzyme and pathway databases

    UniPathwayi UPA00696 .

    Family and domain databases

    Gene3Di 3.20.20.300. 1 hit.
    3.40.50.1700. 2 hits.
    InterProi IPR026891. Fn3-like.
    IPR026892. Glyco_hydro_3.
    IPR019800. Glyco_hydro_3_AS.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    IPR011658. PA14.
    [Graphical view ]
    PANTHERi PTHR30620. PTHR30620. 1 hit.
    Pfami PF14310. Fn3-like. 1 hit.
    PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    PF07691. PA14. 1 hit.
    [Graphical view ]
    PRINTSi PR00133. GLHYDRLASE3.
    SMARTi SM00758. PA14. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 2 hits.
    PROSITEi PS00775. GLYCOSYL_HYDROL_F3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls."
      Bauer S., Vasu P., Persson S., Mort A.J., Somerville C.R.
      Proc. Natl. Acad. Sci. U.S.A. 103:11417-11422(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
    3. "The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
      Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G.
      , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
      Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

    Entry informationi

    Entry nameiBGLI_EMENI
    AccessioniPrimary (citable) accession number: Q5BB53
    Secondary accession number(s): C8VML9, Q1HFU7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 56 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3