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Protein

Rhamnogalacturonan acetylesterase

Gene

AN2528

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a key role in the degradation of rhamnogalacturonan in the cell wall. Involved in degradation of pectin.2 Publications

Catalytic activityi

Hydrolytic cleavage of 2-O-acetyl- or 3-O-acetyl groups of alpha-D-galacturonic acid in rhamnogalacturonan I.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei26NucleophileBy similarity1
Active sitei204By similarity1
Active sitei207By similarity1

GO - Molecular functioni

  • rhamnogalacturonan acetylesterase activity Source: UniProtKB

GO - Biological processi

  • pectin catabolic process Source: UniProtKB

Keywordsi

Molecular functionHydrolase

Protein family/group databases

mycoCLAPiRAE12A_EMENI

Names & Taxonomyi

Protein namesi
Recommended name:
Rhamnogalacturonan acetylesterase1 Publication (EC:3.1.1.861 Publication)
Short name:
RGAE
Gene namesi
ORF Names:AN2528
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome VII
  • UP000005890 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_000043272118 – 245Rhamnogalacturonan acetylesteraseAdd BLAST228

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi100 ↔ 108By similarity
Disulfide bondi226 ↔ 244By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiQ5BAA2

Interactioni

Protein-protein interaction databases

STRINGi162425.CADANIAP00009256

Structurei

3D structure databases

ProteinModelPortaliQ5BAA2
SMRiQ5BAA2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'GDSL' lipolytic enzyme family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000199666
KOiK15530
OMAiQMGHNDA
OrthoDBiEOG092C4HKG

Family and domain databases

Gene3Di3.40.50.1110, 1 hit
InterProiView protein in InterPro
IPR013830 SGNH_hydro
IPR036514 SGNH_hydro_sf
PfamiView protein in Pfam
PF13472 Lipase_GDSL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5BAA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSIALTSLS LLPSALAQTI YLAGDSTMAS STPGWGDYIA DSVSVEISNQ
60 70 80 90 100
AIGGRSARSY TREGRFQAIA DVLQAGDYVV IEFGHNDGGS LSNDNGRTDC
110 120 130 140 150
PGDGDETCET VYNGVAETVL TFPAYIENAA LLFLEKGANV LISSQTPNNP
160 170 180 190 200
WESGTFSYTP NRFVGYAELA AQRAGVDYVD HGAYTASIFE ALGADTVNSF
210 220 230 240
YPNDHTHTNA EGSSVVADAF LKAVVCSGVA LNDVLTRTDF DGECL
Length:245
Mass (Da):25,870
Last modified:April 26, 2005 - v1
Checksum:iE0D993BAC02EBACD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001307 Genomic DNA Translation: CBF87034.1
AACD01000043 Genomic DNA Translation: EAA64633.1
RefSeqiXP_660132.1, XM_655040.1

Genome annotation databases

EnsemblFungiiCADANIAT00009256; CADANIAP00009256; CADANIAG00009256
EAA64633; EAA64633; AN2528.2
GeneIDi2874587
KEGGiani:AN2528.2

Similar proteinsi

Entry informationi

Entry nameiRHA1_EMENI
AccessioniPrimary (citable) accession number: Q5BAA2
Secondary accession number(s): C8VPL0, Q1HFU5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 2015
Last sequence update: April 26, 2005
Last modified: May 23, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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