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Protein

Glucan endo-1,6-beta-glucosidase B

Gene

exgB

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. Acts on lutean, pustulan and 1,6-oligo-beta-D-glucosides.1 Publication

Catalytic activityi

Random hydrolysis of (1->6)-linkages in (1->6)-beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei228Proton donorBy similarity1
Active sitei330NucleophileBy similarity1

GO - Molecular functioni

  • glucan endo-1,6-beta-glucosidase activity Source: ASPGD

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan endo-1,6-beta-glucosidase B (EC:3.2.1.75)
Alternative name(s):
Beta-1,6-glucanase B
Endo-1,6-beta-D-glucanase B
Endo-1,6-beta-glucanase B
Gene namesi
Name:exgB
ORF Names:AN3777
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome II
  • UP000005890 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_000039471017 – 409Glucan endo-1,6-beta-glucosidase BAdd BLAST393

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi35N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ5B6Q3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000217590.
InParanoidiQ5B6Q3.
OMAiLHIQMMD.
OrthoDBiEOG092C2511.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5B6Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFILPLFTS LPVALAWLPG IDKDIYSAAG TNIFNVTSAS SKRWLPASKK
60 70 80 90 100
IRGVNLGSHF VIEPWMASMA WSNMGCSGQR SEFDCVMALG QETADQAFAD
110 120 130 140 150
HWGSWITQDD INQMVQYGLN TIRIPVGYWL KEDLVYADSE HFPKGGIGYL
160 170 180 190 200
EDVCGWASDA GMYIIIDLHG APGAQQPKQP FTGQYAPNPG FYQDYQYDRA
210 220 230 240 250
LEFLEWMTTS IHQNNKFRNV GMLEIVNEPV QNADQASSMI NSYYPSAFTR
260 270 280 290 300
IRNTESSLGI TSNNYLHIQM MNEKWGSGDP TQSLTDNYFA AYDDHRYVKW
310 320 330 340 350
DSSVAVDKES YISASCVDDR GGNWPTIVGE WSLSVPDNVE HTADWEPSSN
360 370 380 390 400
TDFYARWFAA QAIAYEKQEG WVFWSWKAQL GDYRWSYKDA VDAGVIPKDL

DSIYDYSPC
Length:409
Mass (Da):46,267
Last modified:April 26, 2005 - v1
Checksum:i83704098EDC15087
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ490491 mRNA. Translation: ABF50867.1.
AACD01000061 Genomic DNA. Translation: EAA59985.1.
BN001302 Genomic DNA. Translation: CBF75405.1.
RefSeqiXP_661381.1. XM_656289.1.

Genome annotation databases

EnsemblFungiiCADANIAT00004938; CADANIAP00004938; CADANIAG00004938.
EAA59985; EAA59985; AN3777.2.
GeneIDi2873201.
KEGGiani:AN3777.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ490491 mRNA. Translation: ABF50867.1.
AACD01000061 Genomic DNA. Translation: EAA59985.1.
BN001302 Genomic DNA. Translation: CBF75405.1.
RefSeqiXP_661381.1. XM_656289.1.

3D structure databases

ProteinModelPortaliQ5B6Q3.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADANIAT00004938; CADANIAP00004938; CADANIAG00004938.
EAA59985; EAA59985; AN3777.2.
GeneIDi2873201.
KEGGiani:AN3777.2.

Phylogenomic databases

HOGENOMiHOG000217590.
InParanoidiQ5B6Q3.
OMAiLHIQMMD.
OrthoDBiEOG092C2511.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiEXGB_EMENI
AccessioniPrimary (citable) accession number: Q5B6Q3
Secondary accession number(s): C8V716, Q1HFT3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: April 26, 2005
Last modified: November 30, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.