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Protein

DNA ligase

Gene

ANIA_04883

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ANIA_04883Imported
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)Imported
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome III

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi162425.CADANIAP00005522

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006
KOiK10747
OMAiGIMVKIL
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

Q5B3J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPAKKRKR DTQPTRSIAS FFQGQTAKQT EKSEQLASLA DTEQHLSDEA
60 70 80 90 100
LARKLQAEWN NEQDFASPAT VPHSEPTAAS PSPEKDREQK KAKVGVLSLQ
110 120 130 140 150
SSTGTEDTIS LSVPFDQSPL VFDSSRYAGE LKAHWSAEGG NASYALLTRA
160 170 180 190 200
FVLANSTTSR IKIVDTLVNF LRVLIEGDPS SVLPAVWLAT NSISPPYHEL
210 220 230 240 250
ELGLGGSSIS KAFKKIYGLN SQGLKSLYDR LGDAGDVAFE AKKRQSFTLI
260 270 280 290 300
KPKPLSIKGV YQSLIKIAMS KGSGSQELKQ RIVEKLLQDT RGAEESRYIV
310 320 330 340 350
RTLVQNLRIG AVKTTMLIAL ARAFLVSKPD NATFTVHSQH ELARLKKEEL
360 370 380 390 400
AEIYSSAEEL VKASYARHPN YNDLVPCLLE IGVTEELLLR CGLQLHIPLM
410 420 430 440 450
PMLGSITRDL SEMLTKLQGR DFTCEFKYDG QRAQVHCDEA GKVSIFSRHL
460 470 480 490 500
EEMTEKYPDL VSLVPQIRGE GVSSFILEGE VVAVDQNGEL QPFQILTNRA
510 520 530 540 550
KKNVDIGEIK INVCLFAFDL MYLNGAPLLE RSLRERRELL RSLFMEIPNR
560 570 580 590 600
FTWVKSLDAT SADSEAVLDF FKSATENKCE GIMVKVLDNT LATNGSDSTN
610 620 630 640 650
SSITATPKAE AKETKKGGRR KALLSSYEPD KRLESWLKVK KDYSASSETL
660 670 680 690 700
DLIPVAGWHG NGRKAKWWSP ILLAVRNPET GGLQAVTKCM SGFSDKFYQA
710 720 730 740 750
NKEKYEEGSP NVISRPSYVE YNGEPDVWFE PQEVWEMAFA DITLSPTYPA
760 770 780 790 800
AIGLRFSDRS LQGISPMPVD DLQLCYRWQE NVKGRILAER ASAESIVATQ
810
LKRPYVALMN IIDYQT
Length:816
Mass (Da):90,777
Last modified:April 26, 2005 - v1
Checksum:iF3B92F444A46C6EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001303 Genomic DNA Translation: CBF76559.1
RefSeqiXP_662487.1, XM_657395.1

Genome annotation databases

EnsemblFungiiCADANIAT00005522; CADANIAP00005522; CADANIAG00005522
EAA60961; EAA60961; AN4883.2
GeneIDi2872686
KEGGiani:AN4883.2

Similar proteinsi

Entry informationi

Entry nameiQ5B3J7_EMENI
AccessioniPrimary (citable) accession number: Q5B3J7
Secondary accession number(s): C8V9T7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health