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Protein

Alpha-xylosidase

Gene

agdD

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the liberation of alpha-xylose from the non-reducing terminal glucose of xyloglucan oligosaccharides.1 Publication

Catalytic activityi

Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei434 – 4341By similarity
Active sitei437 – 4371By similarity
Active sitei501 – 5011Proton donorBy similarity

GO - Molecular functioni

GO - Biological processi

  • xyloglucan metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.
mycoCLAPiAXL31A_EMENI.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-xylosidase1 Publication (EC:3.2.1.1771 Publication)
Gene namesi
Name:agdD1 Publication
Synonyms:axlA
ORF Names:AN7505
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome IV
  • UP000005890 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AN7505.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 780780Alpha-xylosidasePRO_0000432722Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi48 – 481N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi84 – 841N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi247 – 2471N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi298 – 2981N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi443 – 4431N-linked (GlcNAc...)PROSITE-ProRule annotation
Glycosylationi718 – 7181N-linked (GlcNAc...)PROSITE-ProRule annotation

Keywords - PTMi

Glycoprotein

Expressioni

Inductioni

Despite the presence of an amyR-binding consensus sequence in the promoter, is not activated by isomaltose.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ5AW25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.Curated

Phylogenomic databases

HOGENOMiHOG000221907.
KOiK01811.
OMAiWIYKRWV.
OrthoDBiEOG092C0W89.

Family and domain databases

Gene3Di3.20.20.70. 2 hits.
InterProiIPR013785. Aldolase_TIM.
IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5AW25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFTEGMWLL REGIRIDWMS NVERLNVDKD TVNLLLNKFQ RHRGDTLNSS
60 70 80 90 100
TVSARVTSPL EGIIGVKLVH WAGGLDNGPH YELNTSAGHT EITHEKGKNL
110 120 130 140 150
KYTSGRLELD INIAPNELAF TFTTGADGQD KRKKLTGHSF RSIGYVGDST
160 170 180 190 200
TPKSQLSDGI FYERQGYTLA ELDLSVGEKL YGLGERFGPF VKNGQSVNIW
210 220 230 240 250
NEDGGTSSEL AYKNIPFYIS SNGYGVFVNH PGKVSLELQS ERTTRVNVSV
260 270 280 290 300
EGEELEYFVI EGKNPKEILK RWTDLTGKPA LVPAWSYGLW LTTSFTTNYS
310 320 330 340 350
ERTVTGFLDG FKDRNLPLSV FHFDCFWMKS YQWCDFEFDA DMFPDAAGYL
360 370 380 390 400
ARLKERGLKL SIWINPYVGQ ASPLFEIGKR EGYFIKRIDG SVWQWDLWQA
410 420 430 440 450
GMAVVDFTNP AACSWYTGHL KRLMDLGIDT FKTDFAERIP FKNITYHDGS
460 470 480 490 500
DPARMHNYYA LLYNKVVYET MTSISGKSNS LLFARSTSVG GQKYPVHWGG
510 520 530 540 550
DCESTYEAMA ESLRGGLSLG LAGYIFWASD IGGFEGTPPP ALYKRWVQFG
560 570 580 590 600
LLSSHSRLHG SSSFRVPWIY GEDCSDVLRD CVKRKISLTP YLLAEALNGH
610 620 630 640 650
RSGTPLMRPM FMEFPEDLNT YPLDTQYMFG SNLLVAPVFS DEGIVTFYVP
660 670 680 690 700
RTPEEEGRKQ WISWFDHGKK YEGGRWYTET HGFDTLPILI RPGSVTPINY
710 720 730 740 750
KLEKPEGNPL DGLEILVNGS IDKEVEIEIV DPETTHKVLK VMTVSERETE
760 770 780
NGVEVIARLD GVDGNENSVK VNWVGHGVTK
Length:780
Mass (Da):87,991
Last modified:April 26, 2005 - v1
Checksum:i74FE33E888FE2391
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001304 Genomic DNA. Translation: CBF79518.1.
AACD01000129 Genomic DNA. Translation: EAA62085.1.
RefSeqiXP_680774.1. XM_675682.1.

Genome annotation databases

EnsemblFungiiCADANIAT00000604; CADANIAP00000604; CADANIAG00000604.
EAA62085; EAA62085; AN7505.2.
GeneIDi2869357.
KEGGiani:AN7505.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BN001304 Genomic DNA. Translation: CBF79518.1.
AACD01000129 Genomic DNA. Translation: EAA62085.1.
RefSeqiXP_680774.1. XM_675682.1.

3D structure databases

ProteinModelPortaliQ5AW25.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.
mycoCLAPiAXL31A_EMENI.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADANIAT00000604; CADANIAP00000604; CADANIAG00000604.
EAA62085; EAA62085; AN7505.2.
GeneIDi2869357.
KEGGiani:AN7505.2.

Organism-specific databases

EuPathDBiFungiDB:AN7505.

Phylogenomic databases

HOGENOMiHOG000221907.
KOiK01811.
OMAiWIYKRWV.
OrthoDBiEOG092C0W89.

Family and domain databases

Gene3Di3.20.20.70. 2 hits.
InterProiIPR013785. Aldolase_TIM.
IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAGDD_EMENI
AccessioniPrimary (citable) accession number: Q5AW25
Secondary accession number(s): C8VBI7, Q1HFR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 2015
Last sequence update: April 26, 2005
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.