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Q5AV15 (BGLJ_EMENI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase J

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase J
Cellobiase J
Gentiobiase J
Gene names
Name:bglJ
ORF Names:AN7865
OrganismEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) [Reference proteome]
Taxonomic identifier227321 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length850 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Contains 1 PA14 domain.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 850850Probable beta-glucosidase J
PRO_0000394894

Regions

Domain424 – 570147PA14

Sites

Active site2541 By similarity

Amino acid modifications

Glycosylation431N-linked (GlcNAc...) Potential
Glycosylation521N-linked (GlcNAc...) Potential
Glycosylation5081N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q5AV15 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: D960EA3EBBFA8555

FASTA85092,696
        10         20         30         40         50         60 
MYRQEATTVT ILAQAPPNWP APAFDISGFT SAFRPSRRAQ RSNTTMGSID TNSTDAWHTF 

        70         80         90        100        110        120 
AIPRLGIPAM RITDGPNGAR GTRYFNGVPS ACLPCGTALG ATFDTDLLFK LGRLLAAECK 

       130        140        150        160        170        180 
AKGAHVLLGP TINIQRGPLG GRGFESFSED PVLSGNSAAS YCAGVKDLGI VPTLKHLVCN 

       190        200        210        220        230        240 
DQEHERIAVS AMVTERALRE IYLMPFQLAI KNARPGALMT SYNKVNGLHA SEDPGLLNHI 

       250        260        270        280        290        300 
IRKEWGFEGL IMSDWFGTYS VASAVNAGLD LEMPGPTRFR GPALMHALTS NKVSEKTLDD 

       310        320        330        340        350        360 
RVRKVLELVQ LTSRAGIPEY APAQKLDRVE DRVLLRQAAA DSIVLLKNAN EVLPLDPRKK 

       370        380        390        400        410        420 
TLVIGPNADI AAYCGGGSAS LLAYYTVTPR QGIAEKCEEV VFSQGCYGHK ELPLLGDHLK 

       430        440        450        460        470        480 
TETGERGYTF RVYTEPATYE DRQPVDVLHM TNSCAFLMDY SHPKISGDTY YATLEGRFEP 

       490        500        510        520        530        540 
TESGVYELGL TVAGTGLLYI DGELVIDNKT KQRHGTSFFG IGTVEERGER YLEAGRQHHV 

       550        560        570        580        590        600 
FVEYSTAPTS NLKHHGVVSF GPGGVRLGGC RKLDAETAIK QAVQLAAETE QVVVCVGMNG 

       610        620        630        640        650        660 
NWESEGFDRP HMDLPPGTDN LVRAVIEAQP NAVIVVQSGT PVTMPWADQA KALVQAWYGG 

       670        680        690        700        710        720 
SEGGNGIADV LFGDVNPSAK LPLTFPRDIA HNPSYLSYRS ERGRVLYSED VYVGYRYYDK 

       730        740        750        760        770        780 
VKQAPLFHFG HGLSYTTFKL SGLNVQETDP QASDISAEVV QIYVRPPTTA SVGRPVRELK 

       790        800        810        820        830        840 
GYEKTMLHPG ETKEISVTVP MGVATSFWDE GRSAWLSEKG TYAIEVVGTG ERNMLSAPLC 

       850 
VQVSRYWNGL 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae."
Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H. expand/collapse author list , Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.
Nature 438:1105-1115(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
[2]"The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G. expand/collapse author list , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACD01000134 Genomic DNA. Translation: EAA58910.1.
BN001302 Genomic DNA. Translation: CBF73413.1.
RefSeqXP_681134.1. XM_676042.1.

3D structure databases

ProteinModelPortalQ5AV15.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANIAT00003880; CADANIAP00003880; CADANIAG00003880.
GeneID2869049.
KEGGani:AN7865.2.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
OMAYGHKELP.
OrthoDBEOG7H799Q.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 2 hits.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
IPR011658. PA14.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
PF07691. PA14. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SMARTSM00758. PA14. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLJ_EMENI
AccessionPrimary (citable) accession number: Q5AV15
Secondary accession number(s): C8V7D6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: April 26, 2005
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries