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Protein

Probable beta-glucosidase D

Gene

bglD

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi: cellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei324By similarity1

GO - Molecular functioni

GO - Biological processi

  • cellulose catabolic process Source: UniProtKB-UniPathway
  • secondary metabolic process Source: AspGD

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696

Protein family/group databases

CAZyiGH3 Glycoside Hydrolase Family 3

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase D (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase D
Cellobiase D
Gentiobiase D
Gene namesi
Name:bglD
ORF Names:AN7915
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome II
  • UP000005890 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000039410819 – 812Probable beta-glucosidase DAdd BLAST794

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi53N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi188N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi296N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi360N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi384N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi422N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi501N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi592N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi646N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ5AUW5

Interactioni

Protein-protein interaction databases

STRINGi162425.CADANIAP00003933

Structurei

3D structure databases

ProteinModelPortaliQ5AUW5
SMRiQ5AUW5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi191 – 246Gly-richAdd BLAST56
Compositional biasi212 – 262Ser-richAdd BLAST51

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000031215
InParanoidiQ5AUW5
KOiK05349
OMAiDRTELYN
OrthoDBiEOG092C0R1B

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.20.20.300, 2 hits
3.40.50.1700, 1 hit
InterProiView protein in InterPro
IPR026891 Fn3-like
IPR002772 Glyco_hydro_3_C
IPR036881 Glyco_hydro_3_C_sf
IPR001764 Glyco_hydro_3_N
IPR036962 Glyco_hydro_3_N_sf
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF14310 Fn3-like, 1 hit
PF00933 Glyco_hydro_3, 2 hits
PF01915 Glyco_hydro_3_C, 1 hit
PRINTSiPR00133 GLHYDRLASE3
SMARTiView protein in SMART
SM01217 Fn3_like, 1 hit
SUPFAMiSSF51445 SSF51445, 2 hits
SSF52279 SSF52279, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5AUW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVPSLSVLS FLLGTALAAA SNFEAGLLSS GKVSLGDWKS AHEKASQFVA
60 70 80 90 100
KLNTTEKIKL ITGSSVTTTN GETFTALDIL DGDMGAQAYY YVSAFSLSSA
110 120 130 140 150
LAMTWDKEAM YEQGRAIAAE FYGKGIQMVA GPTSQPLGRT PWGGRLVESF
160 170 180 190 200
GPDPYLNGIA TGLETRAYAD VGVIAGAKHF ILNEQETNRT GGMGGGGGAP
210 220 230 240 250
GGGGMGRGAE FSSSVPGGMS PTSSAGAIPS STSTPGGSGM GGGMAGSSAF
260 270 280 290 300
SSSSSSGAPY SSNADDKTLH ETYLWSFYDA VHSGLGGVMC AMTKVNGTLS
310 320 330 340 350
CQSSSLLLDI LKTELGFPGM VWPDTNGQQD ALASAANGLD YGSSSLWSES
360 370 380 390 400
TIEGYLESNN ITEARLNDMA IRNLMGYYYV NLDNGTQPST AAQDDYVDVR
410 420 430 440 450
ANHAKLIRSH GSKSMVLLKN KNNTLPLYKP HKMAIFGSHA RAAVAGPNMQ
460 470 480 490 500
FSVEGSGPTY DGHIATDSGS GQASLPYLIT PENALNIKAS QDGTMLRWIA
510 520 530 540 550
NDTYSSSTGS ALVMQGSSST SVTPSVSAYS ENMDVCLVFI NALAGEGADR
560 570 580 590 600
TELRNTDQDN LINEVADNCD NTVVVINTVG ARILDSWIEH ENVTAVLYGS
610 620 630 640 650
LLGQESGNSI VDVLYGDVNP SGRLTYTIAK TESDYNVDIC YTAQCNFTEG
660 670 680 690 700
NYIDYRYFDA YNVTPRYEFG YGLSYTDFAY SNLHIQGPSA LSTYPTGQLA
710 720 730 740 750
VGGYEDLWDT VAKVTVTIRN AGSLDGAEVP QLYISYPDVA KQPVRQLRGF
760 770 780 790 800
HNVYIKKGQS TKVTFELRRR DISYWDVQHQ KWAVAPGTYE AWVGASSRDL
810
RTHGSFVVKT KA
Length:812
Mass (Da):86,383
Last modified:May 18, 2010 - v2
Checksum:iA70CFB5FF35CBD1B
GO

Sequence cautioni

The sequence EAA59569 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACD01000135 Genomic DNA Translation: EAA59569.1 Sequence problems.
BN001302 Genomic DNA Translation: CBF73514.1
RefSeqiXP_681184.1, XM_676092.1

Genome annotation databases

EnsemblFungiiCADANIAT00003933; CADANIAP00003933; CADANIAG00003933
EAA59569; EAA59569; AN7915.2
GeneIDi2869248
KEGGiani:AN7915.2

Similar proteinsi

Entry informationi

Entry nameiBGLD_EMENI
AccessioniPrimary (citable) accession number: Q5AUW5
Secondary accession number(s): C8V4V5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: May 18, 2010
Last modified: May 23, 2018
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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