Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5ASE0

- XKS1_EMENI

UniProt

Q5ASE0 - XKS1_EMENI

Protein

Probable D-xylulose kinase A

Gene

xkiA

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.By similarity

    Catalytic activityi

    ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei103 – 1031SubstrateBy similarity
    Binding sitei174 – 1741SubstrateBy similarity
    Binding sitei290 – 2901SubstrateBy similarity
    Binding sitei291 – 2911SubstrateBy similarity
    Binding sitei373 – 3731ATPBy similarity
    Binding sitei484 – 4841ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi480 – 4812ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. xylulokinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Xylose metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable D-xylulose kinase A (EC:2.7.1.17)
    Short name:
    Xylulokinase A
    Gene namesi
    Name:xkiA
    ORF Names:AN8790
    OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
    Taxonomic identifieri227321 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000000560: Chromosome III

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 581581Probable D-xylulose kinase APRO_0000393524Add
    BLAST

    Expressioni

    Inductioni

    By D-xylose, L-arabinose or L-arabitol.

    Interactioni

    Protein-protein interaction databases

    STRINGi162425.CADANIAP00006272.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ASE0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FGGY kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG1070.
    HOGENOMiHOG000174850.
    KOiK00854.
    OMAiGSYSPID.
    OrthoDBiEOG7CRTZN.

    Family and domain databases

    InterProiIPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view]
    PfamiPF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ASE0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSRSSSPLK GPLYIGFDLS TQQLKGLVVN SDLKVVYSSI FDFDADSQGF    50
    PIKKGVLTNE AEHEVFAPVA LWLQALDSVL DGLKKQGLDF SHVRGISGAG 100
    QQHGSVYWGQ DAEKLLNGLD AGKRLQEQLE GAFSHPYSPN WQDSSTQKEC 150
    DEFDEYLGGA DKLAEATGSK AHHRFTGPQI LRFQKKYPDV YKKTSRISLV 200
    SSFLASLFLG HIAPLDISDV CGMNLWNIHK GAYDEDLLKL CAGPHGVEDL 250
    KRKLGDVPED GGIDLGKVHR YYVDRYGFSP ECTVIPSTGD NPATILALPL 300
    RPSDAMVSLG TSTTFLMSTP SYKADPATHF FNHPTTPGLY MFMLCYKNGG 350
    LAREKIRDAI NDAKNEKNPS NPWANFDSVA LQTPPLGQTS PSDPMKMGLF 400
    FPRPEIVPNL RAGQWLFNYD PSTGNLTETL NGEGWNRPAD EARAIIESQM 450
    LSLRLRSRGL TSSPGGDIPA QPRRVYLVGG GSKNKTIAKI AGEILGGSEG 500
    VYKLEIGDNA CALGAAYKAV WALERKKDQT FEDLIGARWH EEEFIEKIAD 550
    GYQKEAFERY GKAVEGFEKM EQRVLEQEGR K 581
    Length:581
    Mass (Da):64,025
    Last modified:April 26, 2005 - v1
    Checksum:i551C8D374CDEF3D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACD01000161 Genomic DNA. Translation: EAA60583.1.
    BN001303 Genomic DNA. Translation: CBF78014.1.
    RefSeqiXP_682059.1. XM_676967.1.

    Genome annotation databases

    EnsemblFungiiCADANIAT00006272; CADANIAP00006272; CADANIAG00006272.
    GeneIDi2868421.
    KEGGiani:AN8790.2.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACD01000161 Genomic DNA. Translation: EAA60583.1 .
    BN001303 Genomic DNA. Translation: CBF78014.1 .
    RefSeqi XP_682059.1. XM_676967.1.

    3D structure databases

    ProteinModelPortali Q5ASE0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 162425.CADANIAP00006272.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANIAT00006272 ; CADANIAP00006272 ; CADANIAG00006272 .
    GeneIDi 2868421.
    KEGGi ani:AN8790.2.

    Phylogenomic databases

    eggNOGi COG1070.
    HOGENOMi HOG000174850.
    KOi K00854.
    OMAi GSYSPID.
    OrthoDBi EOG7CRTZN.

    Family and domain databases

    InterProi IPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view ]
    Pfami PF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
    2. "The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
      Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G.
      , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
      Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENOME REANNOTATION.
      Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

    Entry informationi

    Entry nameiXKS1_EMENI
    AccessioniPrimary (citable) accession number: Q5ASE0
    Secondary accession number(s): C8V9P8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 20, 2010
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3