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Q5AQ12

- CAF20_CANAL

UniProt

Q5AQ12 - CAF20_CANAL

Protein

Cap-associated protein CAF20

Gene

CAF20

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA By similarity.By similarity

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. negative regulation of translation Source: UniProtKB-KW

    Keywords - Molecular functioni

    Initiation factor, Protein synthesis inhibitor

    Keywords - Biological processi

    Protein biosynthesis, Translation regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cap-associated protein CAF20
    Gene namesi
    Name:CAF20
    ORF Names:CaO19.4796
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0004617. orf19.4796.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 176176Cap-associated protein CAF20PRO_0000330084Add
    BLAST

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0004617.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CAF20 family.Curated

    Phylogenomic databases

    eggNOGiNOG47886.
    KOiK03261.
    OrthoDBiEOG7Z3FHB.

    Sequencei

    Sequence statusi: Complete.

    Q5AQ12-1 [UniParc]FASTAAdd to Basket

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    MAKYTEEQLL ELKSEAHTPK PEILDAFNKL IEEVKESIEQ HQQHQRKWHN    50
    GDTYIDEHGH ERSYHHINRR RQSKGASGVP RPNLRKKSEP VVDEDGWATL 100
    SKPKKGSFAE GDAIEERIKF RETNNSGAGI KARPNNKNLG SSKAVDPREI 150
    ASDKQTKAFN AFAALGDEDD DDEDDE 176
    Length:176
    Mass (Da):20,000
    Last modified:April 26, 2005 - v1
    Checksum:i8FB349339071C0E5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000001 Genomic DNA. Translation: EAL04784.1.
    RefSeqiXP_723482.1. XM_718389.1.

    Genome annotation databases

    GeneIDi3634805.
    KEGGical:CaO19.4796.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000001 Genomic DNA. Translation: EAL04784.1 .
    RefSeqi XP_723482.1. XM_718389.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0004617.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3634805.
    KEGGi cal:CaO19.4796.

    Organism-specific databases

    CGDi CAL0004617. orf19.4796.

    Phylogenomic databases

    eggNOGi NOG47886.
    KOi K03261.
    OrthoDBi EOG7Z3FHB.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiCAF20_CANAL
    AccessioniPrimary (citable) accession number: Q5AQ12
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3