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Q5AQ12

- CAF20_CANAL

UniProt

Q5AQ12 - CAF20_CANAL

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Protein

Cap-associated protein CAF20

Gene
CAF20, CaO19.4796
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA By similarity.

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-KW

GO - Biological processi

  1. negative regulation of translation Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor, Protein synthesis inhibitor

Keywords - Biological processi

Protein biosynthesis, Translation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Cap-associated protein CAF20
Gene namesi
Name:CAF20
ORF Names:CaO19.4796
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0004617. orf19.4796.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Cap-associated protein CAF20PRO_0000330084Add
BLAST

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0004617.

Family & Domainsi

Sequence similaritiesi

Belongs to the CAF20 family.

Phylogenomic databases

eggNOGiNOG47886.
KOiK03261.
OrthoDBiEOG7Z3FHB.

Sequencei

Sequence statusi: Complete.

Q5AQ12-1 [UniParc]FASTAAdd to Basket

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MAKYTEEQLL ELKSEAHTPK PEILDAFNKL IEEVKESIEQ HQQHQRKWHN    50
GDTYIDEHGH ERSYHHINRR RQSKGASGVP RPNLRKKSEP VVDEDGWATL 100
SKPKKGSFAE GDAIEERIKF RETNNSGAGI KARPNNKNLG SSKAVDPREI 150
ASDKQTKAFN AFAALGDEDD DDEDDE 176
Length:176
Mass (Da):20,000
Last modified:April 26, 2005 - v1
Checksum:i8FB349339071C0E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000001 Genomic DNA. Translation: EAL04784.1.
RefSeqiXP_723482.1. XM_718389.1.

Genome annotation databases

GeneIDi3634805.
KEGGical:CaO19.4796.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000001 Genomic DNA. Translation: EAL04784.1 .
RefSeqi XP_723482.1. XM_718389.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0004617.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3634805.
KEGGi cal:CaO19.4796.

Organism-specific databases

CGDi CAL0004617. orf19.4796.

Phylogenomic databases

eggNOGi NOG47886.
KOi K03261.
OrthoDBi EOG7Z3FHB.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiCAF20_CANAL
AccessioniPrimary (citable) accession number: Q5AQ12
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 26, 2005
Last modified: November 13, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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