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Q5APK7

- NAR1_CANAL

UniProt

Q5APK7 - NAR1_CANAL

Protein

Cytosolic Fe-S cluster assembly factor NAR1

Gene

NAR1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi20 – 201Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi83 – 831Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi86 – 861Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi89 – 891Iron-sulfur 1 (4Fe-4S)Sequence Analysis
    Metal bindingi205 – 2051Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi260 – 2601Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi497 – 4971Iron-sulfur 2 (4Fe-4S)Sequence Analysis
    Metal bindingi501 – 5011Iron-sulfur 2 (4Fe-4S)Sequence Analysis

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. iron-sulfur cluster binding Source: UniProtKB
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. iron-sulfur cluster assembly Source: UniProtKB

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytosolic Fe-S cluster assembly factor NAR1
    Alternative name(s):
    Nuclear architecture-related protein 1
    Gene namesi
    Name:NAR1
    ORF Names:CaO19.12221, CaO19.4757
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0004486. NAR1.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 609609Cytosolic Fe-S cluster assembly factor NAR1PRO_0000383721Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0004486.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5APK7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NARF family.Curated

    Phylogenomic databases

    eggNOGiCOG4624.
    OrthoDBiEOG7X6M97.

    Family and domain databases

    InterProiIPR009016. Fe_hydrogenase.
    IPR004108. Fe_hydrogenase_lsu_C.
    [Graphical view]
    PfamiPF02906. Fe_hyd_lg_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF53920. SSF53920. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q5APK7-1 [UniParc]FASTAAdd to Basket

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    MSALLSADDL NDFISPGVAC IKPLASSSTN TTTTTNTTDS YNENGEVEIQ    50
    IDSQGNPLEI SKIDDKQFQT NKLTPAQISL ADCLACSGCI TSAEEVLVAQ 100
    HSHQELIKAL QSQKETNKVF VVSISHQSRA SLAMAYNVSI ENMDKCLIDL 150
    FIRQMGFTYI VGTSLGRKLS LINEAKEIIN RKTKGSGTGG IDSDSSSGPI 200
    LSSICPGWVL YAEKTHPYII PKMSTVKSPQ QITGCLLKNL TSNSLNIEKS 250
    KIYHLSIMPC FDKKLESARP EVYEEEEEEE EEKDKALVSV PDVDCVITAK 300
    ELITLLEECP QYQLIPPTLP QEELIGGGCL SMTEIYKQYA PPNWPFIEIS 350
    WSNDSGSASG GYAYNYLTIY RNDLILKGYD GNKFTINLIN GRNPDIYEMR 400
    LMYNGENKEK LASAAVVNGF RNIQNLVRKL KPNTGKTTNT TTTTTKSKVN 450
    PLAARRRARM ANNRGKPETK STSEVNSQEM EIVADASKVD YVEIMACPNG 500
    CINGGGQISA PNTTTTTSIT LPQKEIEKQW INAVLEKYNS IPMFDLSSQS 550
    SSSSSPNEII KFIEWSKKFE NQFNISDNRL FKTHFNPVEK NIIMSVDDPA 600
    TALLVGSKW 609
    Length:609
    Mass (Da):67,319
    Last modified:April 26, 2005 - v1
    Checksum:i7A275ECC2ED88A7C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000002 Genomic DNA. Translation: EAL04550.1.
    AACQ01000001 Genomic DNA. Translation: EAL04745.1.
    RefSeqiXP_723254.1. XM_718161.1.
    XP_723443.1. XM_718350.1.

    Genome annotation databases

    GeneIDi3634916.
    3635018.
    KEGGical:CaO19.12221.
    cal:CaO19.4757.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000002 Genomic DNA. Translation: EAL04550.1 .
    AACQ01000001 Genomic DNA. Translation: EAL04745.1 .
    RefSeqi XP_723254.1. XM_718161.1.
    XP_723443.1. XM_718350.1.

    3D structure databases

    ProteinModelPortali Q5APK7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0004486.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3634916.
    3635018.
    KEGGi cal:CaO19.12221.
    cal:CaO19.4757.

    Organism-specific databases

    CGDi CAL0004486. NAR1.

    Phylogenomic databases

    eggNOGi COG4624.
    OrthoDBi EOG7X6M97.

    Family and domain databases

    InterProi IPR009016. Fe_hydrogenase.
    IPR004108. Fe_hydrogenase_lsu_C.
    [Graphical view ]
    Pfami PF02906. Fe_hyd_lg_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53920. SSF53920. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiNAR1_CANAL
    AccessioniPrimary (citable) accession number: Q5APK7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3