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Q5APK7

- NAR1_CANAL

UniProt

Q5APK7 - NAR1_CANAL

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Protein

Cytosolic Fe-S cluster assembly factor NAR1

Gene

NAR1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi20 – 201Iron-sulfur 1 (4Fe-4S)Sequence Analysis
Metal bindingi83 – 831Iron-sulfur 1 (4Fe-4S)Sequence Analysis
Metal bindingi86 – 861Iron-sulfur 1 (4Fe-4S)Sequence Analysis
Metal bindingi89 – 891Iron-sulfur 1 (4Fe-4S)Sequence Analysis
Metal bindingi205 – 2051Iron-sulfur 2 (4Fe-4S)Sequence Analysis
Metal bindingi260 – 2601Iron-sulfur 2 (4Fe-4S)Sequence Analysis
Metal bindingi497 – 4971Iron-sulfur 2 (4Fe-4S)Sequence Analysis
Metal bindingi501 – 5011Iron-sulfur 2 (4Fe-4S)Sequence Analysis

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. iron-sulfur cluster binding Source: UniProtKB
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. iron-sulfur cluster assembly Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytosolic Fe-S cluster assembly factor NAR1
Alternative name(s):
Nuclear architecture-related protein 1
Gene namesi
Name:NAR1
ORF Names:CaO19.12221, CaO19.4757
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0004486. NAR1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 609609Cytosolic Fe-S cluster assembly factor NAR1PRO_0000383721Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0004486.

Structurei

3D structure databases

ProteinModelPortaliQ5APK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NARF family.Curated

Phylogenomic databases

eggNOGiCOG4624.
InParanoidiQ5APK7.
OrthoDBiEOG7X6M97.

Family and domain databases

InterProiIPR009016. Fe_hydrogenase.
IPR004108. Fe_hydrogenase_lsu_C.
[Graphical view]
PfamiPF02906. Fe_hyd_lg_C. 1 hit.
[Graphical view]
SUPFAMiSSF53920. SSF53920. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5APK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSALLSADDL NDFISPGVAC IKPLASSSTN TTTTTNTTDS YNENGEVEIQ
60 70 80 90 100
IDSQGNPLEI SKIDDKQFQT NKLTPAQISL ADCLACSGCI TSAEEVLVAQ
110 120 130 140 150
HSHQELIKAL QSQKETNKVF VVSISHQSRA SLAMAYNVSI ENMDKCLIDL
160 170 180 190 200
FIRQMGFTYI VGTSLGRKLS LINEAKEIIN RKTKGSGTGG IDSDSSSGPI
210 220 230 240 250
LSSICPGWVL YAEKTHPYII PKMSTVKSPQ QITGCLLKNL TSNSLNIEKS
260 270 280 290 300
KIYHLSIMPC FDKKLESARP EVYEEEEEEE EEKDKALVSV PDVDCVITAK
310 320 330 340 350
ELITLLEECP QYQLIPPTLP QEELIGGGCL SMTEIYKQYA PPNWPFIEIS
360 370 380 390 400
WSNDSGSASG GYAYNYLTIY RNDLILKGYD GNKFTINLIN GRNPDIYEMR
410 420 430 440 450
LMYNGENKEK LASAAVVNGF RNIQNLVRKL KPNTGKTTNT TTTTTKSKVN
460 470 480 490 500
PLAARRRARM ANNRGKPETK STSEVNSQEM EIVADASKVD YVEIMACPNG
510 520 530 540 550
CINGGGQISA PNTTTTTSIT LPQKEIEKQW INAVLEKYNS IPMFDLSSQS
560 570 580 590 600
SSSSSPNEII KFIEWSKKFE NQFNISDNRL FKTHFNPVEK NIIMSVDDPA

TALLVGSKW
Length:609
Mass (Da):67,319
Last modified:April 26, 2005 - v1
Checksum:i7A275ECC2ED88A7C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000002 Genomic DNA. Translation: EAL04550.1.
AACQ01000001 Genomic DNA. Translation: EAL04745.1.
RefSeqiXP_723254.1. XM_718161.1.
XP_723443.1. XM_718350.1.

Genome annotation databases

GeneIDi3634916.
3635018.
KEGGical:CaO19.12221.
cal:CaO19.4757.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000002 Genomic DNA. Translation: EAL04550.1 .
AACQ01000001 Genomic DNA. Translation: EAL04745.1 .
RefSeqi XP_723254.1. XM_718161.1.
XP_723443.1. XM_718350.1.

3D structure databases

ProteinModelPortali Q5APK7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0004486.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3634916.
3635018.
KEGGi cal:CaO19.12221.
cal:CaO19.4757.

Organism-specific databases

CGDi CAL0004486. NAR1.

Phylogenomic databases

eggNOGi COG4624.
InParanoidi Q5APK7.
OrthoDBi EOG7X6M97.

Family and domain databases

InterProi IPR009016. Fe_hydrogenase.
IPR004108. Fe_hydrogenase_lsu_C.
[Graphical view ]
Pfami PF02906. Fe_hyd_lg_C. 1 hit.
[Graphical view ]
SUPFAMi SSF53920. SSF53920. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiNAR1_CANAL
AccessioniPrimary (citable) accession number: Q5APK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3