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Protein

Cytosolic Fe-S cluster assembly factor NAR1

Gene

NAR1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi20Iron-sulfur 1 (4Fe-4S)Sequence analysis1
Metal bindingi82Iron-sulfur 1 (4Fe-4S)Sequence analysis1
Metal bindingi85Iron-sulfur 1 (4Fe-4S)Sequence analysis1
Metal bindingi88Iron-sulfur 1 (4Fe-4S)Sequence analysis1
Metal bindingi204Iron-sulfur 2 (4Fe-4S)Sequence analysis1
Metal bindingi259Iron-sulfur 2 (4Fe-4S)Sequence analysis1
Metal bindingi496Iron-sulfur 2 (4Fe-4S)Sequence analysis1
Metal bindingi500Iron-sulfur 2 (4Fe-4S)Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytosolic Fe-S cluster assembly factor NAR1
Alternative name(s):
Nuclear architecture-related protein 1
Gene namesi
Name:NAR1
Ordered Locus Names:CAALFM_C109010WA
ORF Names:CaO19.12221, CaO19.4757
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 1

Organism-specific databases

CGDiCAL0000185143. NAR1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003837211 – 607Cytosolic Fe-S cluster assembly factor NAR1Add BLAST607

Proteomic databases

PRIDEiQ5APK7.

Structurei

3D structure databases

ProteinModelPortaliQ5APK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NARF family.Curated

Phylogenomic databases

InParanoidiQ5APK7.
OrthoDBiEOG092C2MTS.

Family and domain databases

InterProiView protein in InterPro
IPR009016. Fe_hydrogenase.
IPR004108. Fe_hydrogenase_lsu_C.
PfamiView protein in Pfam
PF02906. Fe_hyd_lg_C. 1 hit.
SUPFAMiSSF53920. SSF53920. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5APK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALLSADDL NDFISPGVAC IKPLASSSTN TTTTNTTDSY NENGEVEIQI
60 70 80 90 100
DSQGNPLEIS KIDDKQFQTN KLTPAQISLA DCLACSGCIT SAEEVLVAQH
110 120 130 140 150
SHQELIKALQ SQKETNKVFV VSISHQSRAS LAMAYNVSIE NMDKCLIDLF
160 170 180 190 200
IRQMGFTYIV GTSLGRKLSL INEAKEIINR KTKGSGTGGI DSDSSSGPIL
210 220 230 240 250
SSICPGWVLY AEKTHPYIIP KMSTVKSPQQ ITGCLLKNLT SNSLNIEKSK
260 270 280 290 300
IYHLSIMPCF DKKLESARPE VYEEEEEEEE EKDKALVSVP DVDCVITAKE
310 320 330 340 350
LITLLEECPQ YQLIPPTLPQ EELIGGGCLS MTEIYKQYAP PNWPFIEISW
360 370 380 390 400
SNDSGSASGG YAYNYLTIYR NDLILKGYDG NKFTINLING RNPDIYEMRL
410 420 430 440 450
MYNGENKEKL ASAAVVNGFR NIQNLVRKLK PNTGKSTNTT TTTTKSKVNP
460 470 480 490 500
LAARRRARIA NNRGKPETKS TSEVNSQEME IVADASKVDY VEIMACPNGC
510 520 530 540 550
INGGGQISAP NTTTTSITLP QKEIEKQWIN AVLEKYNSIP MFDLSSQSSS
560 570 580 590 600
SSSPNEIIKF IEWSKKFENQ FNISDNRLFK THFNPVEKNI IMSVDDPATA

LLVGSKW
Length:607
Mass (Da):67,085
Last modified:May 10, 2017 - v2
Checksum:i1532950F0CBA38EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017623 Genomic DNA. Translation: AOW26536.1.
RefSeqiXP_723443.2. XM_718350.2.

Genome annotation databases

GeneIDi3634916.
KEGGical:CAALFM_C109010WA.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017623 Genomic DNA. Translation: AOW26536.1.
RefSeqiXP_723443.2. XM_718350.2.

3D structure databases

ProteinModelPortaliQ5APK7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5APK7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3634916.
KEGGical:CAALFM_C109010WA.

Organism-specific databases

CGDiCAL0000185143. NAR1.

Phylogenomic databases

InParanoidiQ5APK7.
OrthoDBiEOG092C2MTS.

Miscellaneous databases

PROiPR:Q5APK7.

Family and domain databases

InterProiView protein in InterPro
IPR009016. Fe_hydrogenase.
IPR004108. Fe_hydrogenase_lsu_C.
PfamiView protein in Pfam
PF02906. Fe_hyd_lg_C. 1 hit.
SUPFAMiSSF53920. SSF53920. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiNAR1_CANAL
AccessioniPrimary (citable) accession number: Q5APK7
Secondary accession number(s): A0A1D8PEJ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 10, 2017
Last modified: June 7, 2017
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.