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Q5AMP4

- Q5AMP4_CANAL

UniProt

Q5AMP4 - Q5AMP4_CANAL

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Protein

Malate dehydrogenase

Gene

MDH1-1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

GO - Molecular functioni

  1. L-malate dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. malate metabolic process Source: InterPro
  3. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
Name:MDH1-1Imported
Synonyms:MDH1Imported
ORF Names:CaO19.12072Imported, CaO19.4602Imported
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)Imported
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0003583. MDH1-1.

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0003583.

Family & Domainsi

Sequence similaritiesi

Belongs to the LDH/MDH superfamily. MDH type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0039.
HOGENOMiHOG000213792.
KOiK00026.
OrthoDBiEOG7GJ6Q7.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11540. PTHR11540. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMiSSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEiPS00068. MDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5AMP4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFSKVATRSF SSSASNAYKV AVLGAGGGIG QPLSLLLKLN HKVTDLALYD
60 70 80 90 100
IRGAPGVAAD VSHVPTNSTV KGYNPDQIEE ALTGSDVIVI PAGVPRKPGM
110 120 130 140 150
TRDDLFNTNA SIVRDLAKAA ADYAPNAAVC IISNPVNSTV PIVAEVFKSK
160 170 180 190 200
GNYNPNKLFG VTTLDVLRAA RFVSEVAGTN PVNENVPVVG GHSGVTIVPL
210 220 230 240 250
LSQTKHKDLS GETRDALVHR IQFGGDEVVQ AKDGAGSATL SMAQAGARFA
260 270 280 290 300
GAVLDGLAGE KDVIECTFVD SPLFKDEGVD FFSTKVTLGV DGVKTVHPIG
310 320 330
EISDYEEAQV KEAKDTLIKN IKKGVDFVAQ NP
Length:332
Mass (Da):34,728
Last modified:April 26, 2005 - v1
Checksum:i939B7EB71311519A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000006 Genomic DNA. Translation: EAL03937.1.
AACQ01000005 Genomic DNA. Translation: EAL04092.1.
RefSeqiXP_722674.1. XM_717581.1.
XP_722820.1. XM_717727.1.

Genome annotation databases

GeneIDi3635558.
3635636.
KEGGical:CaO19.12072.
cal:CaO19.4602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000006 Genomic DNA. Translation: EAL03937.1 .
AACQ01000005 Genomic DNA. Translation: EAL04092.1 .
RefSeqi XP_722674.1. XM_717581.1.
XP_722820.1. XM_717727.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0003583.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3635558.
3635636.
KEGGi cal:CaO19.12072.
cal:CaO19.4602.

Organism-specific databases

CGDi CAL0003583. MDH1-1.

Phylogenomic databases

eggNOGi COG0039.
HOGENOMi HOG000213792.
KOi K00026.
OrthoDBi EOG7GJ6Q7.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProi IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR11540. PTHR11540. 1 hit.
Pfami PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMi SSF56327. SSF56327. 1 hit.
TIGRFAMsi TIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEi PS00068. MDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314Imported and SC5314 / ATCC MYA-2876Imported.

Entry informationi

Entry nameiQ5AMP4_CANAL
AccessioniPrimary (citable) accession number: Q5AMP4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3