Q5AMP4 (Q5AMP4_CANAL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate dehydrogenase RuleBase RU003405
EC=1.1.1.37 RuleBase RU003405

Gene names

Name:	MDH1-1 CGD CAL0003583 CGD orf19.4602
Synonyms:	MDH1 EMBL EAL03937.1
ORF Names:	CaO19.12072 EMBL EAL04092.1, CaO19.4602 EMBL EAL03937.1

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH. RuleBase RU003405
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family. RuleBase RU004065

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle RuleBase RU003405
Ligand	NAD RuleBase RU003405
Molecular function	Oxidoreductase RuleBase RU004065
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro malate metabolic process Inferred from electronic annotation. Source: InterPro tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5AMP4 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 939B7EB71311519A	FASTA	332	34,728
	10 20 30 40 50 60 MFSKVATRSF SSSASNAYKV AVLGAGGGIG QPLSLLLKLN HKVTDLALYD IRGAPGVAAD 70 80 90 100 110 120 VSHVPTNSTV KGYNPDQIEE ALTGSDVIVI PAGVPRKPGM TRDDLFNTNA SIVRDLAKAA 130 140 150 160 170 180 ADYAPNAAVC IISNPVNSTV PIVAEVFKSK GNYNPNKLFG VTTLDVLRAA RFVSEVAGTN 190 200 210 220 230 240 PVNENVPVVG GHSGVTIVPL LSQTKHKDLS GETRDALVHR IQFGGDEVVQ AKDGAGSATL 250 260 270 280 290 300 SMAQAGARFA GAVLDGLAGE KDVIECTFVD SPLFKDEGVD FFSTKVTLGV DGVKTVHPIG 310 320 330 EISDYEEAQV KEAKDTLIKN IKKGVDFVAQ NP

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000006 Genomic DNA. Translation: EAL03937.1. AACQ01000005 Genomic DNA. Translation: EAL04092.1.
RefSeq	XP_722674.1. XM_717581.1. XP_722820.1. XM_717727.1.
3D structure databases
SMR	Q5AMP4. Positions 19-329.
ModBase	Search...
Protein-protein interaction databases
STRING	5476.CAL0003583.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3635558. 3635636.
KEGG	cal:CaO19.12072. cal:CaO19.4602.
Organism-specific databases
CGD	CAL0003583. MDH1-1.
Phylogenomic databases
eggNOG	COG0039.
HOGENOM	HOG000213792.
KO	K00026.
Family and domain databases
Gene3D	3.40.50.720. 1 hit. 3.90.110.10. 1 hit.
InterPro	IPR001557. L-lactate/malate_DH. IPR022383. Lactate/malate_DH_C. IPR001236. Lactate/malate_DH_N. IPR015955. Lactate_DH/Glyco_Ohase_4_C. IPR001252. Malate_DH_AS. IPR010097. Malate_DH_type1. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR11540. PTHR11540. 1 hit. PTHR11540:SF1. PTHR11540:SF1. 1 hit.
Pfam	PF02866. Ldh_1_C. 1 hit. PF00056. Ldh_1_N. 1 hit. [Graphical view]
PIRSF	PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAM	SSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMs	TIGR01772. MDH_euk_gproteo. 1 hit.
PROSITE	PS00068. MDH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5AMP4_CANAL

Accession

Primary (citable) accession number: Q5AMP4

Entry history

Integrated into UniProtKB/TrEMBL:	April 26, 2005
Last sequence update:	April 26, 2005
Last modified:	May 29, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)