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Q5AMP4

- Q5AMP4_CANAL

UniProt

Q5AMP4 - Q5AMP4_CANAL

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Protein
Malate dehydrogenase
Gene
MDH1-1, MDH1, CaO19.12072, CaO19.4602
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + NAD+ = oxaloacetate + NADH.UniRule annotation

GO - Molecular functioni

  1. L-malate dehydrogenase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. malate metabolic process Source: InterPro
  3. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

NADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Malate dehydrogenaseUniRule annotation (EC:1.1.1.37UniRule annotation)
Gene namesi
Name:MDH1-1Imported
Synonyms:MDH1Imported
ORF Names:CaO19.12072Imported, CaO19.4602Imported
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0003583. MDH1-1.

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0003583.

Structurei

3D structure databases

ProteinModelPortaliQ5AMP4.
SMRiQ5AMP4. Positions 19-329.

Family & Domainsi

Sequence similaritiesi

Belongs to the LDH/MDH superfamily. MDH type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0039.
HOGENOMiHOG000213792.
KOiK00026.
OrthoDBiEOG7GJ6Q7.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11540. PTHR11540. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMiSSF56327. SSF56327. 1 hit.
TIGRFAMsiTIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEiPS00068. MDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5AMP4-1 [UniParc]FASTAAdd to Basket

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MFSKVATRSF SSSASNAYKV AVLGAGGGIG QPLSLLLKLN HKVTDLALYD    50
IRGAPGVAAD VSHVPTNSTV KGYNPDQIEE ALTGSDVIVI PAGVPRKPGM 100
TRDDLFNTNA SIVRDLAKAA ADYAPNAAVC IISNPVNSTV PIVAEVFKSK 150
GNYNPNKLFG VTTLDVLRAA RFVSEVAGTN PVNENVPVVG GHSGVTIVPL 200
LSQTKHKDLS GETRDALVHR IQFGGDEVVQ AKDGAGSATL SMAQAGARFA 250
GAVLDGLAGE KDVIECTFVD SPLFKDEGVD FFSTKVTLGV DGVKTVHPIG 300
EISDYEEAQV KEAKDTLIKN IKKGVDFVAQ NP 332
Length:332
Mass (Da):34,728
Last modified:April 26, 2005 - v1
Checksum:i939B7EB71311519A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000006 Genomic DNA. Translation: EAL03937.1.
AACQ01000005 Genomic DNA. Translation: EAL04092.1.
RefSeqiXP_722674.1. XM_717581.1.
XP_722820.1. XM_717727.1.

Genome annotation databases

GeneIDi3635558.
3635636.
KEGGical:CaO19.12072.
cal:CaO19.4602.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000006 Genomic DNA. Translation: EAL03937.1 .
AACQ01000005 Genomic DNA. Translation: EAL04092.1 .
RefSeqi XP_722674.1. XM_717581.1.
XP_722820.1. XM_717727.1.

3D structure databases

ProteinModelPortali Q5AMP4.
SMRi Q5AMP4. Positions 19-329.
ModBasei Search...

Protein-protein interaction databases

STRINGi 5476.CAL0003583.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3635558.
3635636.
KEGGi cal:CaO19.12072.
cal:CaO19.4602.

Organism-specific databases

CGDi CAL0003583. MDH1-1.

Phylogenomic databases

eggNOGi COG0039.
HOGENOMi HOG000213792.
KOi K00026.
OrthoDBi EOG7GJ6Q7.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProi IPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR001252. Malate_DH_AS.
IPR010097. Malate_DH_type1.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR11540. PTHR11540. 1 hit.
Pfami PF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMi SSF56327. SSF56327. 1 hit.
TIGRFAMsi TIGR01772. MDH_euk_gproteo. 1 hit.
PROSITEi PS00068. MDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiQ5AMP4_CANAL
AccessioniPrimary (citable) accession number: Q5AMP4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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