Q5AMN3 (ATG11_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Autophagy-related protein 11

Gene names

Name:	ATG11
ORF Names:	CaO19.4614, CaO19.12084

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	1165 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in cytoplasm to vacuole transport (Cvt) and pexophagy By similarity.
Subunit structure	Homodimer By similarity.
Subcellular location	Vacuole membrane; Peripheral membrane protein By similarity. Note: Vacuolar and perivacuolar punctate structures. Concentrated in a region of the vacuolar membrane that contacts the peroxisome during the engulfment process By similarity.
Sequence similarities	Belongs to the ATG11 family.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Membrane Vacuole
Domain	Coiled coil
Gene Ontology (GO)
Biological process	autophagy Inferred from electronic annotation. Source: UniProtKB-KW protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	vacuolar membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1165	1165	Autophagy-related protein 11		PRO_0000124544
Regions
	Coiled coil	239 – 304	66	Potential
	Coiled coil	670 – 853	184	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5AMN3 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: E4A86AF7A32AAB68	FASTA	1,165	135,262
	10 20 30 40 50 60 MSEISYLSIN NAHNGIIIKI PKPVRFHTLS EFKKYIQQSY SIDSVDNLFL LTTFGIKLNY 70 80 90 100 110 120 NLINEIGEVF VYDKRLFTNI VDQSLIDQYT QSTFRVSEPT HSPLLKSNVG FLKQNLSSNL 130 140 150 160 170 180 KINQGWARII TQDGELMDQY CRELIQQINV IFKCLNTIFQ FATNFTNEIE KNFSNFFNYV 190 200 210 220 230 240 KLINYKTLHK SWITNYKNLK TFPTFKIDNE NIKLSDFLEV DRLQSSADYI EKFLPLIVNK 250 260 270 280 290 300 LNELKQVIET VNEEKLTVDK FIETSRNESI SNFKNVNISN VLSQLQTESQ QLTDDIENLH 310 320 330 340 350 360 YKNMDEIYRL HRDKLSISIY NNAKDIYKNL NDLQQFKNKL TKASLKAFNT IANLQMKMVG 370 380 390 400 410 420 VKTEMKKITT EDETATEDSK VGDVNYKTIS NVKKYEDYLS LTIDLPLIFG FSLIEKRRQF 430 440 450 460 470 480 EWYDFYSKGI VNNVSEQLST IIEHEKVFRG IWLKKFGTLL SLINDDPLTP SLPNIDVTLV 490 500 510 520 530 540 GNRQNNFSIL YDLKIERDDI INYISLIEAT NMSKNFVTLL NKNFKDLIAS TNNMKKVTKV 550 560 570 580 590 600 ISSLSTYTTN SADDKSKSSH EEGTEEEIDF DLNLIKGLKS RIKKLENLLH QQQFKNLNNW 610 620 630 640 650 660 PVIRNVPSMT NDNRQSTIIQ PTVVSPARTN PTQLLSRNPS TTKENTTTNI HNNHQQSEVL 670 680 690 700 710 720 DSSVIDKHLD NIRLKKLNNE LQTKNTELTN QINSKNETIT QQQKEMEHMK LKTEKRVDEL 730 740 750 760 770 780 MKKLQEKDEE CQSLKQENKI KCDEVENLTK KLELSDNHNK ELEAKITEYT QKATSKTKEI 790 800 810 820 830 840 ADLNKTVSNL RSELGDAMHM KNDLLSNLSS KEAEFTKERN QFNNDLKALQ LKLDEINEDY 850 860 870 880 890 900 ENLMELTQAK QKKHDLIIND LNNVIINLMN DIKKTLLSVF EYFLEYCLVL ESMGLLLVKE 910 920 930 940 950 960 DEIYKIKRVK GLKSKKSIGD GDMSIISNGT PSSKVIEEIE NEINIVNNIP PISSILPDSY 970 980 990 1000 1010 1020 SSGTESDSVV DRYNDQSMKL ISTFNQLFKF NNENENENRI DHILNTLAFK NNVQLQEDSI 1030 1040 1050 1060 1070 1080 NDTRFFLNAI SKRFRDVEGF AKRQAKDNKL KEQEHRKLVH RLNSKISVNG FQEKDLVLFL 1090 1100 1110 1120 1130 1140 PTRIDRPNGE NIPSNDKIQP WAAFNIGAPH YFLKTEQTKN KEWIIGRVKK ITEYKVTEEN 1150 1160 VQSLESNPFQ LSVNVTWYLV EADEE

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000006 Genomic DNA. Translation: EAL03949.1. AACQ01000005 Genomic DNA. Translation: EAL04104.1.
RefSeq	XP_722686.1. XM_717593.1. XP_722832.1. XM_717739.1.
3D structure databases
ProteinModelPortal	Q5AMN3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3635544. 3635597.
KEGG	cal:CaO19.12084. cal:CaO19.4614.
Organism-specific databases
CGD	CAL0003613. orf19.4614.
Phylogenomic databases
PhylomeDB	Q5AMN3.
Family and domain databases
InterPro	IPR019460. Autophagy-rel_p11. [Graphical view]
KO	K08330.
Pfam	PF10377. ATG11. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATG11_CANAL

Accession

Primary (citable) accession number: Q5AMN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	April 26, 2005
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program