Q5ALR8 (AMN1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Antagonist of mitotic exit network protein 1

Gene names

Name:	AMN1
ORF Names:	CaO19.1507, CaO19.9083

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Negative regulator of the mitotic exit network (MEN), required for multiple cell cycle checkpoints By similarity. Required for daughter cell separation and chromosome stability By similarity. Involved in copper sensitivity By similarity.
Subcellular location	Cytoplasm By similarity. Nucleus By similarity.
Sequence similarities	Belongs to the AMN1 family.

Ontologies

Keywords
Biological process	Cell cycle Cell division Mitosis
Cellular component	Cytoplasm Nucleus
Gene Ontology (GO)
Biological process	cell division Inferred from electronic annotation. Source: UniProtKB-KW mitosis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 658	658	Antagonist of mitotic exit network protein 1		PRO_0000277842
Regions
	Compositional bias	67 – 73	7	Poly-Gln
	Compositional bias	194 – 203	10	Poly-Gln
	Compositional bias	623 – 652	30	Asn-rich

Sequences

	Sequence		Length	Mass (Da)
	Q5ALR8 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: DF76E44516A22D82	FASTA	658	75,791
	10 20 30 40 50 60 MNFHSTKPLS YDSSDNEIYN PFLVSTNEEG RVSPTIDKQQ QPVLKRAKSI VSSNSLSAFF 70 80 90 100 110 120 TDSKSKQQQQ QQQRDRKRNK DRRNRPGRLR RSHSTNSNDQ FIMNTGSFKL PDQDEFQFTM 130 140 150 160 170 180 NNNSDNGFSS STSSSDLESV PDLTDDNIDE LTPETTPIKP VGNFYFNTLF DNEENTDGYY 190 200 210 220 230 240 YKLNSQIKIR NELQQQQQQQ QQQRLTSSSP SIFEIPEIVY KIISYVDEQN TILPQESTPI 250 260 270 280 290 300 RRNPLSYKHA LLIHGDKKSA QSALQKTTNQ QSQQNQQPSS VISSSPLYNC LLVNKLFYKI 310 320 330 340 350 360 TSEIISTKFY SHNEQQLKKF IENKSHQQQN SSSPIIIQPK TFILHKLFQT KQIIFDQLIE 370 380 390 400 410 420 FINFDQLSWF ELYMCPKISL DKPQSQTFMK IFQSCSNNLT KLIITGSKTI DDEFLMKLGQ 430 440 450 460 470 480 FKCGDNLQIL DLRACELITD FGIYQLSLYC RNLTFINFGR KPISSGNGNG GGNGGGSGRY 490 500 510 520 530 540 ITDNSMIKLI NNNRKLSTIG LAGCHITDKC VWEIANKLPN ISRLSLNNCP KLTNSGINQI 550 560 570 580 590 600 FTLTNTPNSN YFKCLSVLEL RFNHQLTDLT SIIKFKRRQK FQFNIILLLE LCESLMLKYR 610 620 630 640 650 QQEFELDKLI SLKIFQDISH WVNDYNDNDG DLSYNEIKHL INNNNNNNSS NNISTRGF

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000008 Genomic DNA. Translation: EAL03664.1. AACQ01000007 Genomic DNA. Translation: EAL03810.1.
RefSeq	XP_722415.1. XM_717322.1. XP_722553.1. XM_717460.1.
3D structure databases
ProteinModelPortal	Q5ALR8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3635795. 3635886.
KEGG	cal:CaO19.1507. cal:CaO19.9083.
Organism-specific databases
CGD	CAL0005389. orf19.1507.
Phylogenomic databases
PhylomeDB	Q5ALR8.
Family and domain databases
KO	K15081.
ProtoNet	Search...

Entry information

Entry name

AMN1_CANAL

Accession

Primary (citable) accession number: Q5ALR8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	April 26, 2005
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program