Q5AJ92 (RPIA_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase
EC=5.3.1.6

Alternative name(s):
D-ribose-5-phosphate ketol-isomerase
Phosphoriboisomerase

Gene names

Name:	RKI1
ORF Names:	CaO19.1701, CaO19.9268

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 263	263	Ribose-5-phosphate isomerase		PRO_0000339884

Sequences

	Sequence		Length	Mass (Da)
	Q5AJ92 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 8B5E6CFDF8B5326F	FASTA	263	28,790
	10 20 30 40 50 60 MFIRSLYHRI SNTKTITNLI IRNMSSTSKV ESAKKLAAYK AVDENFPKDA KVIGIGSGST 70 80 90 100 110 120 VIYAAERIGQ LDNKDSFICI PTGFQSKQLI IDNGLRLGTI EQYPDIDIAF DGADEVDPQL 130 140 150 160 170 180 NLIKGGGACL FQEKLVAASA KKFVVVADYR KKSDKLGQSW RQGVPIEIVP NSYSKIIQEL 190 200 210 220 230 240 SKKLGAKNVD LRQGGKAKAG PIITDNNNFL LDADFGEIEI DNVGKLHEQI KLLVGVVETG 250 260 LFTNMANKAY FGEEDGSVSV WSK

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000014 Genomic DNA. Translation: EAL02861.1. AACQ01000013 Genomic DNA. Translation: EAL02990.1.
RefSeq	XP_721652.1. XM_716559.1. XP_721773.1. XM_716680.1.
3D structure databases
HSSP	HSSP built from PDB template 1XTZ based on UniProtKB Q12189.
ProteinModelPortal	Q5AJ92.
SMR	Q5AJ92. Positions 31-263.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5AJ92.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3636574. 3636730.
KEGG	cal:CaO19.1701. cal:CaO19.9268.
Phylogenomic databases
PhylomeDB	Q5AJ92.
Family and domain databases
InterPro	IPR004788. Ribose5P_isomerase_typA. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_CANAL

Accession

Primary (citable) accession number: Q5AJ92

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	April 26, 2005
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program