Reviewed, UniProtKB/Swiss-Prot Q5AJ92 (RPIA_CANAL)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase
    D-ribose-5-phosphate ketol-isomerase

Gene names

Name:	RKI1
ORF Names:	CaO19.1701, CaO19.9268

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Isomerase
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 263	263	Ribose-5-phosphate isomerase		PRO_0000339884

Sequences

	Sequence		Length	Mass (Da)
	Q5AJ92-1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 8B5E6CFDF8B5326F	FASTA	263	28,790
	10 20 30 40 50 60 MFIRSLYHRI SNTKTITNLI IRNMSSTSKV ESAKKLAAYK AVDENFPKDA KVIGIGSGST 70 80 90 100 110 120 VIYAAERIGQ LDNKDSFICI PTGFQSKQLI IDNGLRLGTI EQYPDIDIAF DGADEVDPQL 130 140 150 160 170 180 NLIKGGGACL FQEKLVAASA KKFVVVADYR KKSDKLGQSW RQGVPIEIVP NSYSKIIQEL 190 200 210 220 230 240 SKKLGAKNVD LRQGGKAKAG PIITDNNNFL LDADFGEIEI DNVGKLHEQI KLLVGVVETG 250 260 LFTNMANKAY FGEEDGSVSV WSK

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AACQ01000014 Genomic DNA. Translation: EAL02861.1. AACQ01000013 Genomic DNA. Translation: EAL02990.1.
RefSeq	XP_721652.1. XP_721773.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3636574. 3636730.
KEGG	cal:CaO19.1701. cal:CaO19.9268.
Phylogenomic databases
OMA	QEKIVAT.
Family and domain databases
InterPro	IPR004788. RpiA. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
ProDom	PD005813. RpiA. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_CANAL

Accession

Primary (citable) accession number: Q5AJ92

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	April 26, 2005
Last modified:	November 3, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)