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Q5AI37

- ARX1_CANAL

UniProt

Q5AI37 - ARX1_CANAL

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Protein
Probable metalloprotease ARX1
Gene
ARX1, CaO19.10533, CaO19.3015
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm By similarity.

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. metallopeptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metalloprotease ARX1 (EC:3.-.-.-)
Alternative name(s):
Associated with ribosomal export complex protein 1
Gene namesi
Name:ARX1
ORF Names:CaO19.10533, CaO19.3015
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0001348. orf19.3015.

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 564564Probable metalloprotease ARX1
PRO_0000148993Add
BLAST

Interactioni

Subunit structurei

Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles By similarity.

Protein-protein interaction databases

STRINGi5476.CAL0001348.

Structurei

3D structure databases

ProteinModelPortaliQ5AI37.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M24 family.

Phylogenomic databases

eggNOGiCOG0024.
KOiK14813.
OrthoDBiEOG79W9F0.

Family and domain databases

Gene3Di3.90.230.10. 1 hit.
InterProiIPR000994. Pept_M24_structural-domain.
[Graphical view]
PfamiPF00557. Peptidase_M24. 1 hit.
[Graphical view]
SUPFAMiSSF55920. SSF55920. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5AI37-1 [UniParc]FASTAAdd to Basket

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MQLAVRQEDA DILLKQKNVL DELVVEKYRV AGQITQTALA YITSLINNSY    50
HLQTSPKLTI QQLCLLTDSF LLKLLSRQYV NKVNEKGIAH PTTINVNQLL 100
NGFSPEIDDE REFFLNQGDV VTISLGVHID GYTSQVSHTL VIYPPSADAK 150
PEGPLLGSNA DALCACHLAT ESVVVLLGCS LSPEKLPANL KNVSNTVTGS 200
QIRELVDAIA DSFNCVVVPG SKIRRVRRFL AGQAEGIVAE RDFKGVVWDE 250
SHQEARLLKQ SNNTSTDLIL SDSNKPVQTN NSSAIPTDDF VVVPGEVYQI 300
DIRMTGLSDV NEIGIVTTEE IDHFTGKNNK QDFNAKSSIF IRDFAVTHQL 350
KLKTSKKLLG EIDRQFSVYP FKLDYASKNF PINTESSEDE IKQQIAAIGQ 400
DMKSNRLGAA ELSNRHLIQP KPIQTTKFIP LKEILLSANP TGKHGIDATK 450
PVLPGMEIPL PNLGVSSLKL KSLLKTGRSI NNVRESTTVA INENNQELIR 500
LTGGEATAKS NWVHSQYKLP ASLNETIGQL VQISKDKRFG IKIKEVVPYK 550
VQQSNMSVES MQID 564
Length:564
Mass (Da):62,233
Last modified:April 26, 2005 - v1
Checksum:i1B95FF8831F0CCA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000015 Genomic DNA. Translation: EAL02715.1.
AACQ01000017 Genomic DNA. Translation: EAL02435.1.
RefSeqiXP_721242.1. XM_716149.1.
XP_721513.1. XM_716420.1.

Genome annotation databases

GeneIDi3636811.
3637175.
KEGGical:CaO19.10533.
cal:CaO19.3015.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000015 Genomic DNA. Translation: EAL02715.1 .
AACQ01000017 Genomic DNA. Translation: EAL02435.1 .
RefSeqi XP_721242.1. XM_716149.1.
XP_721513.1. XM_716420.1.

3D structure databases

ProteinModelPortali Q5AI37.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0001348.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3636811.
3637175.
KEGGi cal:CaO19.10533.
cal:CaO19.3015.

Organism-specific databases

CGDi CAL0001348. orf19.3015.

Phylogenomic databases

eggNOGi COG0024.
KOi K14813.
OrthoDBi EOG79W9F0.

Family and domain databases

Gene3Di 3.90.230.10. 1 hit.
InterProi IPR000994. Pept_M24_structural-domain.
[Graphical view ]
Pfami PF00557. Peptidase_M24. 1 hit.
[Graphical view ]
SUPFAMi SSF55920. SSF55920. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiARX1_CANAL
AccessioniPrimary (citable) accession number: Q5AI37
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi