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Q5AI37

- ARX1_CANAL

UniProt

Q5AI37 - ARX1_CANAL

Protein

Probable metalloprotease ARX1

Gene

ARX1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm By similarity.By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. metallopeptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Metalloprotease, Protease

    Keywords - Ligandi

    Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable metalloprotease ARX1 (EC:3.-.-.-)
    Alternative name(s):
    Associated with ribosomal export complex protein 1
    Gene namesi
    Name:ARX1
    ORF Names:CaO19.10533, CaO19.3015
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0001348. orf19.3015.

    Subcellular locationi

    Cytoplasm By similarity. Nucleus By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 564564Probable metalloprotease ARX1PRO_0000148993Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles.By similarity

    Protein-protein interaction databases

    STRINGi5476.CAL0001348.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5AI37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase M24 family.Curated

    Phylogenomic databases

    eggNOGiCOG0024.
    KOiK14813.
    OrthoDBiEOG79W9F0.

    Family and domain databases

    Gene3Di3.90.230.10. 1 hit.
    InterProiIPR000994. Pept_M24_structural-domain.
    [Graphical view]
    PfamiPF00557. Peptidase_M24. 1 hit.
    [Graphical view]
    SUPFAMiSSF55920. SSF55920. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5AI37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQLAVRQEDA DILLKQKNVL DELVVEKYRV AGQITQTALA YITSLINNSY    50
    HLQTSPKLTI QQLCLLTDSF LLKLLSRQYV NKVNEKGIAH PTTINVNQLL 100
    NGFSPEIDDE REFFLNQGDV VTISLGVHID GYTSQVSHTL VIYPPSADAK 150
    PEGPLLGSNA DALCACHLAT ESVVVLLGCS LSPEKLPANL KNVSNTVTGS 200
    QIRELVDAIA DSFNCVVVPG SKIRRVRRFL AGQAEGIVAE RDFKGVVWDE 250
    SHQEARLLKQ SNNTSTDLIL SDSNKPVQTN NSSAIPTDDF VVVPGEVYQI 300
    DIRMTGLSDV NEIGIVTTEE IDHFTGKNNK QDFNAKSSIF IRDFAVTHQL 350
    KLKTSKKLLG EIDRQFSVYP FKLDYASKNF PINTESSEDE IKQQIAAIGQ 400
    DMKSNRLGAA ELSNRHLIQP KPIQTTKFIP LKEILLSANP TGKHGIDATK 450
    PVLPGMEIPL PNLGVSSLKL KSLLKTGRSI NNVRESTTVA INENNQELIR 500
    LTGGEATAKS NWVHSQYKLP ASLNETIGQL VQISKDKRFG IKIKEVVPYK 550
    VQQSNMSVES MQID 564
    Length:564
    Mass (Da):62,233
    Last modified:April 26, 2005 - v1
    Checksum:i1B95FF8831F0CCA8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000015 Genomic DNA. Translation: EAL02715.1.
    AACQ01000017 Genomic DNA. Translation: EAL02435.1.
    RefSeqiXP_721242.1. XM_716149.1.
    XP_721513.1. XM_716420.1.

    Genome annotation databases

    GeneIDi3636811.
    3637175.
    KEGGical:CaO19.10533.
    cal:CaO19.3015.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000015 Genomic DNA. Translation: EAL02715.1 .
    AACQ01000017 Genomic DNA. Translation: EAL02435.1 .
    RefSeqi XP_721242.1. XM_716149.1.
    XP_721513.1. XM_716420.1.

    3D structure databases

    ProteinModelPortali Q5AI37.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0001348.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3636811.
    3637175.
    KEGGi cal:CaO19.10533.
    cal:CaO19.3015.

    Organism-specific databases

    CGDi CAL0001348. orf19.3015.

    Phylogenomic databases

    eggNOGi COG0024.
    KOi K14813.
    OrthoDBi EOG79W9F0.

    Family and domain databases

    Gene3Di 3.90.230.10. 1 hit.
    InterProi IPR000994. Pept_M24_structural-domain.
    [Graphical view ]
    Pfami PF00557. Peptidase_M24. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55920. SSF55920. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiARX1_CANAL
    AccessioniPrimary (citable) accession number: Q5AI37
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. Peptidase families
      Classification of peptidase families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3