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Q5AI37 (ARX1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable metalloprotease ARX1

EC=3.-.-.-
Alternative name(s):
Associated with ribosomal export complex protein 1
Gene names
Name:ARX1
ORF Names:CaO19.10533, CaO19.3015
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm By similarity.

Subunit structure

Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the peptidase M24 family.

Ontologies

Keywords
   Cellular componentCytoplasm
Nucleus
   LigandMetal-binding
   Molecular functionHydrolase
Metalloprotease
Protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

metallopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 564564Probable metalloprotease ARX1
PRO_0000148993

Sequences

Sequence LengthMass (Da)Tools
Q5AI37 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 1B95FF8831F0CCA8

FASTA56462,233
        10         20         30         40         50         60 
MQLAVRQEDA DILLKQKNVL DELVVEKYRV AGQITQTALA YITSLINNSY HLQTSPKLTI 

        70         80         90        100        110        120 
QQLCLLTDSF LLKLLSRQYV NKVNEKGIAH PTTINVNQLL NGFSPEIDDE REFFLNQGDV 

       130        140        150        160        170        180 
VTISLGVHID GYTSQVSHTL VIYPPSADAK PEGPLLGSNA DALCACHLAT ESVVVLLGCS 

       190        200        210        220        230        240 
LSPEKLPANL KNVSNTVTGS QIRELVDAIA DSFNCVVVPG SKIRRVRRFL AGQAEGIVAE 

       250        260        270        280        290        300 
RDFKGVVWDE SHQEARLLKQ SNNTSTDLIL SDSNKPVQTN NSSAIPTDDF VVVPGEVYQI 

       310        320        330        340        350        360 
DIRMTGLSDV NEIGIVTTEE IDHFTGKNNK QDFNAKSSIF IRDFAVTHQL KLKTSKKLLG 

       370        380        390        400        410        420 
EIDRQFSVYP FKLDYASKNF PINTESSEDE IKQQIAAIGQ DMKSNRLGAA ELSNRHLIQP 

       430        440        450        460        470        480 
KPIQTTKFIP LKEILLSANP TGKHGIDATK PVLPGMEIPL PNLGVSSLKL KSLLKTGRSI 

       490        500        510        520        530        540 
NNVRESTTVA INENNQELIR LTGGEATAKS NWVHSQYKLP ASLNETIGQL VQISKDKRFG 

       550        560 
IKIKEVVPYK VQQSNMSVES MQID 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000015 Genomic DNA. Translation: EAL02715.1.
AACQ01000017 Genomic DNA. Translation: EAL02435.1.
RefSeqXP_721242.1. XM_716149.1.
XP_721513.1. XM_716420.1.

3D structure databases

ProteinModelPortalQ5AI37.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0001348.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3636811.
3637175.
KEGGcal:CaO19.10533.
cal:CaO19.3015.

Organism-specific databases

CGDCAL0001348. orf19.3015.

Phylogenomic databases

eggNOGCOG0024.
KOK14813.
OrthoDBEOG79W9F0.

Family and domain databases

Gene3D3.90.230.10. 1 hit.
InterProIPR000994. Pept_M24_structural-domain.
[Graphical view]
PfamPF00557. Peptidase_M24. 1 hit.
[Graphical view]
SUPFAMSSF55920. SSF55920. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARX1_CANAL
AccessionPrimary (citable) accession number: Q5AI37
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries

Candida albicans

Candida albicans: entries and gene names