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Protein

Probable metalloprotease ARX1

Gene

ARX1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probable metalloprotease involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit. Accompanies the pre-60S particles to the cytoplasm (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Metalloprotease, Protease
LigandMetal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable metalloprotease ARX1 (EC:3.-.-.-)
Alternative name(s):
Associated with ribosomal export complex protein 1
Gene namesi
Name:ARX1
Ordered Locus Names:CAALFM_C103230CA
ORF Names:CaO19.10533, CaO19.3015
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 1

Organism-specific databases

CGDiCAL0000194302 ARX1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001489931 – 564Probable metalloprotease ARX1Add BLAST564

Proteomic databases

PRIDEiQ5AI37

Interactioni

Subunit structurei

Component of the nucleoplasmic and cytoplasmic pre-60S ribosomal particles.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ5AI37
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M24 family.Curated

Phylogenomic databases

InParanoidiQ5AI37
KOiK14813
OMAiCAAHIAT
OrthoDBiEOG092C2TAV

Family and domain databases

InterProiView protein in InterPro
IPR036005 Creatinase/aminopeptidase-like
IPR000994 Pept_M24
PfamiView protein in Pfam
PF00557 Peptidase_M24, 1 hit
SUPFAMiSSF55920 SSF55920, 1 hit

Sequencei

Sequence statusi: Complete.

Q5AI37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLAVRQEDA DILLKQKNVL DELVVEKYRV AGQITQTALA YITSLINNSY
60 70 80 90 100
HLQTSPKLTI QQLCLLTDSF LLKLLSRQYV NKVNEKGIAH PTTINVNQLL
110 120 130 140 150
NGFSPEIDDE REFFLNQGDV VTISLGVHID GYTSQVSHTL VIYPPSADAK
160 170 180 190 200
PEGPLLGSNA DALCACHLAT ESVVVLLGCS LSPEKLPANL KNVSNTVTGS
210 220 230 240 250
QIRELVDAIA DSFNCVVVPG SKIRRVRRFL AGQAEGIVAE RDFKGVVWDE
260 270 280 290 300
SHQEARLLKQ SNNTSTDLIL SDSNKPVQTN NSSAIPTDDF VVVPGEVYQI
310 320 330 340 350
DIRMTGLSDV NEIGIVTTEE IDHFTGKNNK QDFNAKSSIF IRDFAVTHQL
360 370 380 390 400
KLKTSKKLLG EIDRQFSVYP FKLDYASKNF PINTESSEDE IKQQIAAIGQ
410 420 430 440 450
DMKSNRLGAA ELSNRHLIQP KPIQTTKFIP LKEILLSANP TGKHGIDATK
460 470 480 490 500
PVLPGMEIPL PNLGVSSLKL KSLLKTGRSI NNVRESTTVA INENNQELIR
510 520 530 540 550
LTGGEATAKS NWVHSQYKLP ASLNETIGQL VQISKDKRFG IKIKEVVPYK
560
VQQSNMSVES MQID
Length:564
Mass (Da):62,233
Last modified:April 26, 2005 - v1
Checksum:i1B95FF8831F0CCA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017623 Genomic DNA Translation: AOW26004.1
RefSeqiXP_721513.1, XM_716420.1

Genome annotation databases

EnsemblFungiiAOW26004; AOW26004; CAALFM_C103230CA
GeneIDi3636811
KEGGical:CAALFM_C103230CA

Similar proteinsi

Entry informationi

Entry nameiARX1_CANAL
AccessioniPrimary (citable) accession number: Q5AI37
Secondary accession number(s): A0A1D8PCY6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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