Q5AI21 (SEC62_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translocation protein SEC62

Gene names

Name:	SEC62
ORF Names:	CaO19.10549, CaO19.3031

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for preprotein translocation By similarity.
Subunit structure	Part of a complex that contains SEC61, SEC62, SEC63, SEC66 and SEC72 By similarity.
Subcellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the SEC62 family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Endoplasmic reticulum Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to endoplasmic reticulum membrane Inferred from electronic annotation. Source: InterPro plasma membrane Inferred from direct assay PubMed 19824013. Source: CGD
Molecular_function	protein transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	Translocation protein SEC62		PRO_0000206621
Regions
	Topological domain	1 – 150	150	Cytoplasmic Potential
	Transmembrane	151 – 171	21	Helical; Potential
	Topological domain	172 – 185	14	Lumenal Potential
	Transmembrane	186 – 206	21	Helical; Potential
	Topological domain	207 – 293	87	Cytoplasmic Potential
	Compositional bias	241 – 249	9	Poly-Lys

Sequences

	Sequence		Length	Mass (Da)
	Q5AI21 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: B4CC4BBA36824ED0	FASTA	293	33,286
	10 20 30 40 50 60 MSAPTPPQTG QFQVATSAQR SPVAVNIVNY LFQNPILKQR TGLLDNTNDI EFFRFKRLQR 70 80 90 100 110 120 ALLSDDYKQK QQNPKNGLIP VANNEDVQKV FVLLIQNQLL LPLQKLHYAE VKAVKGWKPN 130 140 150 160 170 180 KEKPTLKRAD KAVMDPDVYY GWLYQKPNPY ILLYSFLAIA GVFAVILFPL WPNFMKRGVW 190 200 210 220 230 240 YLSMGALGLI ALFFATAIVR LIIYIISLVA FPKPFWLFPN LFEDCGVIES FQPVYAWEEP 250 260 270 280 290 KKKKGKKKKE PKLEVVEEKV GSSSGDVKVT GSELSNGSST TGKRKVTLEE VEE

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000017 Genomic DNA. Translation: EAL02451.1. AACQ01000015 Genomic DNA. Translation: EAL02731.1.
RefSeq	XP_721258.1. XM_716165.1. XP_721529.1. XM_716436.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5476.CAL0001383.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3636860. 3637124.
KEGG	cal:CaO19.10549. cal:CaO19.3031.
Organism-specific databases
CGD	CAL0001383. orf19.3031.
Phylogenomic databases
eggNOG	COG5232.
KO	K12275.
Family and domain databases
InterPro	IPR004728. Sec62. IPR011553. Sec62_asco. [Graphical view]
PANTHER	PTHR12443. PTHR12443. 1 hit.
Pfam	PF03839. Sec62. 1 hit. [Graphical view]
TIGRFAMs	TIGR00869. sec62. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SEC62_CANAL

Accession

Primary (citable) accession number: Q5AI21

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2006
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program