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Q5AFK5 (Q5AFK5_CANAL) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:THG1 EMBL EAL01510.1
ORF Names:CaO19.7063 EMBL EAL01510.1, orf19.7063 CGD CAL0002111
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length268 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding27 – 348ATP PDB 3WBZ
Nucleotide binding27 – 348GTP PDB 3WC0
Nucleotide binding44 – 474ATP PDB 3WBZ
Nucleotide binding92 – 954ATP PDB 3WBZ
Nucleotide binding92 – 954GTP PDB 3WC0

Sites

Metal binding291Magnesium PDB 3WBZ PDB 3WC0
Metal binding301Magnesium PDB 3WBZ PDB 3WC0
Metal binding761Magnesium PDB 3WBZ PDB 3WC0
Binding site101ATP PDB 3WBZ
Binding site101GTP PDB 3WC0
Binding site431GTP; via carbonyl oxygen PDB 3WC0
Binding site471GTP; via amide nitrogen PDB 3WC0
Binding site761ATP PDB 3WBZ
Binding site761GTP PDB 3WC0
Binding site1321ATP PDB 3WBZ
Binding site1321GTP PDB 3WC0
Binding site1521ATP PDB 3WBZ

Sequences

Sequence LengthMass (Da)Tools
Q5AFK5 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 0BC7B911C05C49EB

FASTA26832,442
        10         20         30         40         50         60 
MANSKYEYVK LFEKENYLLP DTYIIIRVDG KGFHKFSQFY EFEKPNDLKA LQVMNSAAEK 

        70         80         90        100        110        120 
LMSKYSDVML AYGDSDEYSF LLRKNCQLYE RREMKLTTLF SSLMSTYYMY FWSQYFPDKP 

       130        140        150        160        170        180 
LHIDHLPNFD ARAVLYPDFK HIRNYFSWRQ VDCHINNLYN TTFWNLVLKL KMTPQQAEQR 

       190        200        210        220        230        240 
LMGTVASDKN EILFKECGVN YNNESEMYKK GTIIVREFEN YETEDEAELS KRQVQRLEKK 

       250        260 
RKKAELKIYH VDIINDDSWW KSRPWLKD 

« Hide

References

« Hide 'large scale' references
[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.
[2]"Structural basis of reverse nucleotide polymerization."
Nakamura A., Nemoto T., Heinemann I.U., Yamashita K., Sonoda T., Komoda K., Tanaka I., Soll D., Yao M.
Proc. Natl. Acad. Sci. U.S.A. 110:20970-20975(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.39 ANGSTROMS) IN COMPLEX WITH ATP; GTP AND MAGNESIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000024 Genomic DNA. Translation: EAL01510.1.
RefSeqXP_720355.1. XM_715262.1.
XP_888688.1. XM_883595.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3WBZX-ray2.39A/B/C/D/E/F/G/H1-268[»]
3WC0X-ray3.03A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P1-268[»]
3WC1X-ray4.18A/B/C/D1-262[»]
3WC2X-ray3.64A/B/C/D1-268[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0002111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3637997.
3704204.
KEGGcal:CaO19.7063.
cal:CaO19_7063.

Organism-specific databases

CGDCAL0002111. orf19.7063.

Phylogenomic databases

eggNOGCOG4021.
KOK10761.
OrthoDBEOG7QVMD6.

Family and domain databases

InterProIPR025845. Thg1_C_dom.
IPR024956. tRNAHis_GuaTrfase_cat.
IPR007537. tRNAHis_GuaTrfase_Thg1.
[Graphical view]
PANTHERPTHR12729. PTHR12729. 1 hit.
PfamPF04446. Thg1. 1 hit.
PF14413. Thg1C. 1 hit.
[Graphical view]
PIRSFPIRSF028980. tRNAHis_guanylyltransferase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5AFK5_CANAL
AccessionPrimary (citable) accession number: Q5AFK5
Secondary accession number(s): Q3MPS5
Entry history
Integrated into UniProtKB/TrEMBL: April 26, 2005
Last sequence update: April 26, 2005
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)