Q5AC37 (PRP45_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pre-mRNA-processing protein 45

Gene names

Name:	PRP45
ORF Names:	CaO19.12959, CaO19.5513

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in pre-mRNA splicing By similarity.
Subunit structure	Associated with the spliceosome By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the SNW family.

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Nucleus Spliceosome
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mRNA splicing, via spliceosome Inferred from electronic annotation. Source: InterPro
Cellular_component	spliceosomal complex Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	Pre-mRNA-processing protein 45		PRO_0000084816

Sequences

	Sequence		Length	Mass (Da)
	Q5AC37 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: EE23347794848E77	FASTA	286	33,200
	10 20 30 40 50 60 MASCNLLVIQ TTSIIMFSSL LSRPVNSSYD PSYHFSPVTR EIKNDPTSNG VVSTTKNATP 70 80 90 100 110 120 LAPSKYDTTI PLKKRYPNLV HNFPKPELDE NVILETKKII DSILNPSDEP TNDINYIKYE 130 140 150 160 170 180 NPNPNPNPNP NPNQEQQQQS SSSSSKIIQI KQFQEDPMLP PKFKLRKNRH ERIIEDVTFV 190 200 210 220 230 240 KDLKTKKLTK EDREFWNIPA AVSNWKNSQG FTIGLDKRMI GREHVPIEMN IEKFNDLSTA 250 260 270 280 LSDADLQARE DLKQRNEIRQ QKQLQEKRLR DEKIKEIANR SKRRRY

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000034 Genomic DNA. Translation: EAL00180.1. AACQ01000033 Genomic DNA. Translation: EAL00302.1.
RefSeq	XP_719078.1. XM_713985.1. XP_719195.1. XM_714102.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5476.CAL0006088.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3639050. 3639166.
KEGG	cal:CaO19.12959. cal:CaO19.5513.
Organism-specific databases
CGD	CAL0006088. orf19.5513.
Phylogenomic databases
eggNOG	NOG295848.
KO	K06063.
Family and domain databases
InterPro	IPR017862. SKI-int_prot_SKIP. IPR004015. SKI-int_prot_SKIP_SNW-dom. [Graphical view]
PANTHER	PTHR12096. PTHR12096. 1 hit.
Pfam	PF02731. SKIP_SNW. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PRP45_CANAL

Accession

Primary (citable) accession number: Q5AC37

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 13, 2005
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program