Q5ABE5 (ALG13_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UDP-N-acetylglucosamine transferase subunit ALG13
EC=2.4.1.141

Alternative name(s):
Asparagine-linked glycosylation protein 13

Gene names

Name:	ALG13
ORF Names:	CaO19.6025, CaO19.13446

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	293 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway By similarity.
Catalytic activity	UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.
Subunit structure	Heterodimer with ALG14 to form a functional enzyme By similarity.
Subcellular location	Endoplasmic reticulum By similarity.
Sequence similarities	Belongs to the glycosyltransferase 28 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological process	lipid glycosylation Inferred from electronic annotation. Source: InterPro
Cellular component	endoplasmic reticulum Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity Inferred from electronic annotation. Source: EC carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 293	293	UDP-N-acetylglucosamine transferase subunit ALG13		PRO_0000215598

Sequences

	Sequence		Length	Mass (Da)
	Q5ABE5 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: C1E73B93B067A6BE	FASTA	293	34,270
	10 20 30 40 50 60 MFDWRRLKPL RPHQIFFFYT TIQNYSDNGY QYSYKSNQIK SNQIKLNQQQ QTSRQLIRIN 70 80 90 100 110 120 NQLPPSVVLH NIIMKSILIT TGATITFESL IQIIVSPQFL NNLIRLKINK LIIQYGHEIK 130 140 150 160 170 180 NSINLSESFF NETINKYDLI NLFNLEIEET PIGDDDDDEG IRLFKNSDIE ILAFSYSSNI 190 200 210 220 230 240 NKYIENVDLI ISHAGTGSII DCLHLNKPLI VIVNDKLMDN HQLEIAQQFT KLNYCIYYSI 250 260 270 280 290 KELEQYVNNN DNNKDSRFWN QLNQLINGEL QLNKLPQTDG SIIETIICEE LEK

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000036 Genomic DNA. Translation: EAK99981.1. AACQ01000035 Genomic DNA. Translation: EAL00086.1.
RefSeq	XP_718885.1. XM_713792.1. XP_718987.1. XM_713894.1.
3D structure databases
ProteinModelPortal	Q5ABE5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5ABE5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3639346. 3639415.
KEGG	cal:CaO19.13446. cal:CaO19.6025.
Organism-specific databases
CGD	CAL0005072. orf19.6025.
Phylogenomic databases
PhylomeDB	Q5ABE5.
Family and domain databases
InterPro	IPR007235. Glyco_trans_28_C. [Graphical view]
KO	K07432.
Pfam	PF04101. Glyco_tran_28_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALG13_CANAL

Accession

Primary (citable) accession number: Q5ABE5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	April 26, 2005
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program