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Q5ABD0

- SNF7_CANAL

UniProt

Q5ABD0 - SNF7_CANAL

Protein

Vacuolar-sorting protein SNF7

Gene

SNF7

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 5 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.1 Publication

    GO - Biological processi

    1. cellular response to drug Source: CGD
    2. cellular response to lithium ion Source: CGD
    3. cellular response to pH Source: CGD
    4. filamentous growth Source: CGD
    5. filamentous growth of a population of unicellular organisms Source: CGD
    6. filamentous growth of a population of unicellular organisms in response to neutral pH Source: CGD
    7. filamentous growth of a population of unicellular organisms in response to pH Source: CGD
    8. fungal-type cell wall organization Source: CGD
    9. late endosome to vacuole transport Source: CGD
    10. pathogenesis Source: CGD
    11. positive regulation of transcription, DNA-templated Source: CGD
    12. protein processing Source: CGD
    13. protein targeting to vacuole Source: CGD
    14. signal transduction Source: CGD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Vacuolar-sorting protein SNF7
    Alternative name(s):
    Vacuolar protein-sorting-associated protein 32
    Gene namesi
    Name:SNF7
    Synonyms:VPS32
    ORF Names:CaO19.13461, CaO19.6040
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0005125. SNF7.

    Subcellular locationi

    Cytoplasm By similarity. Endosome membrane By similarity; Peripheral membrane protein By similarity

    GO - Cellular componenti

    1. ESCRT III complex Source: CGD

    Keywords - Cellular componenti

    Cytoplasm, Endosome, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226Vacuolar-sorting protein SNF7PRO_0000211437Add
    BLAST

    Interactioni

    Subunit structurei

    A component of the endosomal sorting required for transport complex III (ESCRT-III).By similarity

    Protein-protein interaction databases

    BioGridi1222572. 1 interaction.
    STRINGi5476.CAL0005125.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5ABD0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili18 – 182165Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi209 – 2157Asp/Glu-rich (acidic)

    Sequence similaritiesi

    Belongs to the SNF7 family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG291419.
    KOiK12194.
    OrthoDBiEOG72RN9W.

    Family and domain databases

    InterProiIPR005024. Snf7.
    [Graphical view]
    PfamiPF03357. Snf7. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5ABD0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MWGYFFGGNS QQKKDLPKKA IVELREHIQT LNKKKNHLQQ QMDDQDQLAR    50
    KYVSSKQTTL AKSALKRKKG YESNLLKVEN QIETLETQLI SIEGANLNLE 100
    TMKAMKQGAK AMKQIHGEYD VDKVEDTMDE IREQVELADE ISEAISRPVG 150
    NEFVDEDELD EELKELEAEA KEQEQEHRVP AQKAKPQPVS REEELPQFPS 200
    VNKKAPVVEE DEDEEALKAL QAEMGL 226
    Length:226
    Mass (Da):25,890
    Last modified:April 26, 2005 - v1
    Checksum:i9570B3B1E1C0419F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000035 Genomic DNA. Translation: EAL00101.1.
    AACQ01000036 Genomic DNA. Translation: EAK99996.1.
    RefSeqiXP_718900.1. XM_713807.1.
    XP_719002.1. XM_713909.1.

    Genome annotation databases

    GeneIDi3639377.
    3639478.
    KEGGical:CaO19.13461.
    cal:CaO19.6040.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000035 Genomic DNA. Translation: EAL00101.1 .
    AACQ01000036 Genomic DNA. Translation: EAK99996.1 .
    RefSeqi XP_718900.1. XM_713807.1.
    XP_719002.1. XM_713909.1.

    3D structure databases

    ProteinModelPortali Q5ABD0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 1222572. 1 interaction.
    STRINGi 5476.CAL0005125.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3639377.
    3639478.
    KEGGi cal:CaO19.13461.
    cal:CaO19.6040.

    Organism-specific databases

    CGDi CAL0005125. SNF7.

    Phylogenomic databases

    eggNOGi NOG291419.
    KOi K12194.
    OrthoDBi EOG72RN9W.

    Family and domain databases

    InterProi IPR005024. Snf7.
    [Graphical view ]
    Pfami PF03357. Snf7. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.
    2. "Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans."
      Kullas A.L., Li M., Davis D.A.
      Eukaryot. Cell 3:1609-1618(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.

    Entry informationi

    Entry nameiSNF7_CANAL
    AccessioniPrimary (citable) accession number: Q5ABD0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 21, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3