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Q5ABD0

- SNF7_CANAL

UniProt

Q5ABD0 - SNF7_CANAL

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Protein

Vacuolar-sorting protein SNF7

Gene

SNF7

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 5 out of 5- Protein inferred from homologyi

Functioni

Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.1 Publication

GO - Biological processi

  1. cellular response to drug Source: CGD
  2. cellular response to lithium ion Source: CGD
  3. cellular response to pH Source: CGD
  4. filamentous growth Source: CGD
  5. filamentous growth of a population of unicellular organisms Source: CGD
  6. filamentous growth of a population of unicellular organisms in response to neutral pH Source: CGD
  7. filamentous growth of a population of unicellular organisms in response to pH Source: CGD
  8. fungal-type cell wall organization Source: CGD
  9. late endosome to vacuole transport Source: CGD
  10. pathogenesis Source: CGD
  11. positive regulation of transcription, DNA-templated Source: CGD
  12. protein processing Source: CGD
  13. protein targeting to vacuole Source: CGD
  14. signal transduction Source: CGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Vacuolar-sorting protein SNF7
Alternative name(s):
Vacuolar protein-sorting-associated protein 32
Gene namesi
Name:SNF7
Synonyms:VPS32
ORF Names:CaO19.13461, CaO19.6040
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0005125. SNF7.

Subcellular locationi

Cytoplasm By similarity. Endosome membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

  1. ESCRT III complex Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Vacuolar-sorting protein SNF7PRO_0000211437Add
BLAST

Interactioni

Subunit structurei

A component of the endosomal sorting required for transport complex III (ESCRT-III).By similarity

Protein-protein interaction databases

BioGridi1222572. 1 interaction.
STRINGi5476.CAL0005125.

Structurei

3D structure databases

ProteinModelPortaliQ5ABD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili18 – 182165Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi209 – 2157Asp/Glu-rich (acidic)

Sequence similaritiesi

Belongs to the SNF7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG291419.
InParanoidiQ5ABD0.
KOiK12194.
OrthoDBiEOG72RN9W.

Family and domain databases

InterProiIPR005024. Snf7_fam.
[Graphical view]
PfamiPF03357. Snf7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5ABD0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MWGYFFGGNS QQKKDLPKKA IVELREHIQT LNKKKNHLQQ QMDDQDQLAR
60 70 80 90 100
KYVSSKQTTL AKSALKRKKG YESNLLKVEN QIETLETQLI SIEGANLNLE
110 120 130 140 150
TMKAMKQGAK AMKQIHGEYD VDKVEDTMDE IREQVELADE ISEAISRPVG
160 170 180 190 200
NEFVDEDELD EELKELEAEA KEQEQEHRVP AQKAKPQPVS REEELPQFPS
210 220
VNKKAPVVEE DEDEEALKAL QAEMGL
Length:226
Mass (Da):25,890
Last modified:April 26, 2005 - v1
Checksum:i9570B3B1E1C0419F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000035 Genomic DNA. Translation: EAL00101.1.
AACQ01000036 Genomic DNA. Translation: EAK99996.1.
RefSeqiXP_718900.1. XM_713807.1.
XP_719002.1. XM_713909.1.

Genome annotation databases

GeneIDi3639377.
3639478.
KEGGical:CaO19.13461.
cal:CaO19.6040.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000035 Genomic DNA. Translation: EAL00101.1 .
AACQ01000036 Genomic DNA. Translation: EAK99996.1 .
RefSeqi XP_718900.1. XM_713807.1.
XP_719002.1. XM_713909.1.

3D structure databases

ProteinModelPortali Q5ABD0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 1222572. 1 interaction.
STRINGi 5476.CAL0005125.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3639377.
3639478.
KEGGi cal:CaO19.13461.
cal:CaO19.6040.

Organism-specific databases

CGDi CAL0005125. SNF7.

Phylogenomic databases

eggNOGi NOG291419.
InParanoidi Q5ABD0.
KOi K12194.
OrthoDBi EOG72RN9W.

Family and domain databases

InterProi IPR005024. Snf7_fam.
[Graphical view ]
Pfami PF03357. Snf7. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.
  2. "Snf7p, a component of the ESCRT-III protein complex, is an upstream member of the RIM101 pathway in Candida albicans."
    Kullas A.L., Li M., Davis D.A.
    Eukaryot. Cell 3:1609-1618(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiSNF7_CANAL
AccessioniPrimary (citable) accession number: Q5ABD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: April 26, 2005
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3