SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5AAJ7

- SWC4_CANAL

UniProt

Q5AAJ7 - SWC4_CANAL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
SWR1-complex protein 4
Gene
SWC4, CaO19.7492
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair By similarity.

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. chromatin binding Source: InterPro

GO - Biological processi

  1. DNA repair Source: UniProtKB-KW
  2. chromatin remodeling Source: InterPro
  3. histone H2A acetylation Source: InterPro
  4. histone H4 acetylation Source: CGD
  5. regulation of transcription, DNA-templated Source: UniProtKB-KW
  6. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Chromatin regulator

Keywords - Biological processi

DNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
SWR1-complex protein 4
Gene namesi
Name:SWC4
ORF Names:CaO19.7492
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0005735. orf19.7492.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. NuA4 histone acetyltransferase complex Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 635635SWR1-complex protein 4
PRO_0000076337Add
BLAST

Proteomic databases

PRIDEiQ5AAJ7.

Interactioni

Subunit structurei

Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex By similarity.

Protein-protein interaction databases

STRINGi5476.CAL0005735.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini303 – 35351SANT
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi177 – 19115Gln-rich
Add
BLAST

Sequence similaritiesi

Belongs to the SWC4 family.
Contains 1 SANT domain.

Phylogenomic databases

eggNOGiNOG298520.
KOiK11324.
OrthoDBiEOG70ZZXC.

Family and domain databases

InterProiIPR009057. Homeodomain-like.
IPR017877. Myb-like_dom.
IPR001005. SANT/Myb.
IPR027109. Swc4/Dmap1.
[Graphical view]
PANTHERiPTHR12855. PTHR12855. 1 hit.
SMARTiSM00717. SANT. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5AAJ7-1 [UniParc]FASTAAdd to Basket

« Hide

MSANDILDVL NIQRDESNQP PKKKQKSSST PTLPDGKQLT GMARELYNLV    50
GPNTPPINLN SNSYTANKEK MKKFKPSPWT RMPFTPKQGI ELNHWVKGSK 100
ELIEQQEFEE DGTPKPYFFE KYNVQLEIPE FVDEDTYDLY MIEIKEYESK 150
MKEERARREK ERKEREKRDL EEKKKKQQQQ QQKSQQNPQN QIKDDEKNQD 200
TRNNTDKKDS EQKSEDKPTV EAKKETDEKK DDVVLKDNTN ETKPVTETTK 250
SETETTEQNN SEKTNENETN KTNDKDGEGN LTKSKDSATE DQSNNKKEND 300
EDTESEWTYK ETKHLFELCQ AFELKWPIIH DRFPNPNRTA EDLKEQFYRI 350
CIKILENQKN KNQALIDSLK AYCKPRELER KQYLENLLKR TPAEIAEEES 400
LVIEARRFEI AAKKMLMERS NLLTLLDSPQ TTQNVSQYQS SQGITNLYNN 450
LLIYDKHQKK KQMANKSNPQ QEPVPPPIPL AASSSVKRDR GFQTQLQQYL 500
SSFLKQNHHT NPAVKQEINS IQQLLMKRLT QKEEEAYGLY FHGTEKLNPG 550
VMLRSQQKLP GLNQRQSILK SVNILLQEMD IPTGGGTSWK PIMPTRKTMA 600
KYDELIRSVV TLLDVKKAKD KLESEIKLIK SQRGL 635
Length:635
Mass (Da):74,039
Last modified:April 26, 2005 - v1
Checksum:i63D13B88267DBBF4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000039 Genomic DNA. Translation: EAK99734.1.
RefSeqiXP_718649.1. XM_713556.1.

Genome annotation databases

GeneIDi3639679.
KEGGical:CaO19.7492.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000039 Genomic DNA. Translation: EAK99734.1 .
RefSeqi XP_718649.1. XM_713556.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0005735.

Proteomic databases

PRIDEi Q5AAJ7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3639679.
KEGGi cal:CaO19.7492.

Organism-specific databases

CGDi CAL0005735. orf19.7492.

Phylogenomic databases

eggNOGi NOG298520.
KOi K11324.
OrthoDBi EOG70ZZXC.

Family and domain databases

InterProi IPR009057. Homeodomain-like.
IPR017877. Myb-like_dom.
IPR001005. SANT/Myb.
IPR027109. Swc4/Dmap1.
[Graphical view ]
PANTHERi PTHR12855. PTHR12855. 1 hit.
SMARTi SM00717. SANT. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiSWC4_CANAL
AccessioniPrimary (citable) accession number: Q5AAJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi