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Q5A8H7 (SWC5_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SWR1-complex protein 5
Gene names
Name:SWC5
ORF Names:CaO19.13194, CaO19.5772
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability By similarity.

Subunit structure

Component of the SWR1 chromatin remodeling complex By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the SWC5 family.

Contains 1 BCNT-C domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   Molecular functionActivator
Chromatin regulator
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processchromatin modification

Inferred from electronic annotation. Source: UniProtKB-KW

regulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 338338SWR1-complex protein 5
PRO_0000212503

Regions

Domain251 – 33181BCNT-C
Compositional bias160 – 18324Gln-rich

Sequences

Sequence LengthMass (Da)Tools
Q5A8H7 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 3D495865048B6CF2

FASTA33838,870
        10         20         30         40         50         60 
MSKQNIDKST EHSAGENALS EKNHTIESNK NNIDSEEDDE EDEDYDPEKK NEAENEGGVS 

        70         80         90        100        110        120 
SDEEEDNDQY KDGKTSKIPD YSTIESSTSQ VKTRSQRLHE KLSNQSRFIG NFEVDSKTGL 

       130        140        150        160        170        180 
VKDQSNIDVN SIFENLKNGS PSIDNSEELN IDSEKTANSQ QQQKQQSNIE ENELQGPKQI 

       190        200        210        220        230        240 
KIQINYTFAG KLITETKYVD ENSQEAKAYL NSTSNISSNN SNEDIPYRRS QVKVIRTDPV 

       250        260        270        280        290        300 
TNETKELRIK LKRPSLIDRF LSINGNSKKM KLSTLEKSRL DWASFVDKRN INEELKIHNK 

       310        320        330 
AGYLDKQDFI NRMNSKRDDL YLQAKEKEKI RKQQLLQK 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000047 Genomic DNA. Translation: EAK99100.1.
AACQ01000046 Genomic DNA. Translation: EAK99175.1.
RefSeqXP_718040.1. XM_712947.1.
XP_718107.1. XM_713014.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0001511.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3640268.
3640341.
KEGGcal:CaO19.13194.
cal:CaO19.5772.

Organism-specific databases

CGDCAL0001511. orf19.5772.

Phylogenomic databases

eggNOGNOG296897.
OrthoDBEOG7PP5JH.

Family and domain databases

InterProIPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
[Graphical view]
PANTHERPTHR23227. PTHR23227. 1 hit.
PfamPF07572. BCNT. 1 hit.
[Graphical view]
PROSITEPS51279. BCNT_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSWC5_CANAL
AccessionPrimary (citable) accession number: Q5A8H7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names