Q5A8H7 (SWC5_CANAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SWR1-complex protein 5

Gene names

Name:	SWC5
ORF Names:	CaO19.13194, CaO19.5772

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]

Taxonomic identifier

237561 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida › Candida albicans

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability By similarity.
Subunit structure	Component of the SWR1 chromatin remodeling complex By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the SWC5 family. Contains 1 BCNT-C domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Molecular function	Activator Chromatin regulator
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chromatin modification Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 338	338	SWR1-complex protein 5		PRO_0000212503
Regions
	Domain	251 – 331	81	BCNT-C
	Compositional bias	160 – 183	24	Gln-rich

Sequences

	Sequence		Length	Mass (Da)
	Q5A8H7 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: 3D495865048B6CF2	FASTA	338	38,870
	10 20 30 40 50 60 MSKQNIDKST EHSAGENALS EKNHTIESNK NNIDSEEDDE EDEDYDPEKK NEAENEGGVS 70 80 90 100 110 120 SDEEEDNDQY KDGKTSKIPD YSTIESSTSQ VKTRSQRLHE KLSNQSRFIG NFEVDSKTGL 130 140 150 160 170 180 VKDQSNIDVN SIFENLKNGS PSIDNSEELN IDSEKTANSQ QQQKQQSNIE ENELQGPKQI 190 200 210 220 230 240 KIQINYTFAG KLITETKYVD ENSQEAKAYL NSTSNISSNN SNEDIPYRRS QVKVIRTDPV 250 260 270 280 290 300 TNETKELRIK LKRPSLIDRF LSINGNSKKM KLSTLEKSRL DWASFVDKRN INEELKIHNK 310 320 330 AGYLDKQDFI NRMNSKRDDL YLQAKEKEKI RKQQLLQK

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AACQ01000047 Genomic DNA. Translation: EAK99100.1. AACQ01000046 Genomic DNA. Translation: EAK99175.1.
RefSeq	XP_718040.1. XM_712947.1. XP_718107.1. XM_713014.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5476.CAL0001511.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3640268. 3640341.
KEGG	cal:CaO19.13194. cal:CaO19.5772.
Organism-specific databases
CGD	CAL0001511. orf19.5772.
Phylogenomic databases
eggNOG	NOG296897.
Family and domain databases
InterPro	IPR011421. BCNT-C. IPR027124. Swc5/CFDP. [Graphical view]
PANTHER	PTHR23227. PTHR23227. 1 hit.
Pfam	PF07572. BCNT. 1 hit. [Graphical view]
PROSITE	PS51279. BCNT_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SWC5_CANAL

Accession

Primary (citable) accession number: Q5A8H7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	April 26, 2005
Last modified:	April 3, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program