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Protein

SWR1-complex protein 5

Gene

SWC5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).By similarity

GO - Biological processi

  1. chromatin modification Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Chromatin regulator

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
SWR1-complex protein 5
Gene namesi
Name:SWC5
ORF Names:CaO19.13194, CaO19.5772
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559 Componenti: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0001511. orf19.5772.

Subcellular locationi

  1. Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 338338SWR1-complex protein 5PRO_0000212503Add
BLAST

Interactioni

Subunit structurei

Component of the SWR1 chromatin remodeling complex.By similarity

Protein-protein interaction databases

STRINGi5476.CAL0001511.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini251 – 33181BCNT-CPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi160 – 18324Gln-richAdd
BLAST

Sequence similaritiesi

Belongs to the SWC5 family.Curated
Contains 1 BCNT-C domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG296897.
InParanoidiQ5A8H7.
OrthoDBiEOG7PP5JH.

Family and domain databases

InterProiIPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
[Graphical view]
PANTHERiPTHR23227. PTHR23227. 1 hit.
PfamiPF07572. BCNT. 1 hit.
[Graphical view]
PROSITEiPS51279. BCNT_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5A8H7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQNIDKST EHSAGENALS EKNHTIESNK NNIDSEEDDE EDEDYDPEKK
60 70 80 90 100
NEAENEGGVS SDEEEDNDQY KDGKTSKIPD YSTIESSTSQ VKTRSQRLHE
110 120 130 140 150
KLSNQSRFIG NFEVDSKTGL VKDQSNIDVN SIFENLKNGS PSIDNSEELN
160 170 180 190 200
IDSEKTANSQ QQQKQQSNIE ENELQGPKQI KIQINYTFAG KLITETKYVD
210 220 230 240 250
ENSQEAKAYL NSTSNISSNN SNEDIPYRRS QVKVIRTDPV TNETKELRIK
260 270 280 290 300
LKRPSLIDRF LSINGNSKKM KLSTLEKSRL DWASFVDKRN INEELKIHNK
310 320 330
AGYLDKQDFI NRMNSKRDDL YLQAKEKEKI RKQQLLQK
Length:338
Mass (Da):38,870
Last modified:April 26, 2005 - v1
Checksum:i3D495865048B6CF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000047 Genomic DNA. Translation: EAK99100.1.
AACQ01000046 Genomic DNA. Translation: EAK99175.1.
RefSeqiXP_718040.1. XM_712947.1.
XP_718107.1. XM_713014.1.

Genome annotation databases

GeneIDi3640268.
3640341.
KEGGical:CaO19.13194.
cal:CaO19.5772.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000047 Genomic DNA. Translation: EAK99100.1.
AACQ01000046 Genomic DNA. Translation: EAK99175.1.
RefSeqiXP_718040.1. XM_712947.1.
XP_718107.1. XM_713014.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5476.CAL0001511.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3640268.
3640341.
KEGGical:CaO19.13194.
cal:CaO19.5772.

Organism-specific databases

CGDiCAL0001511. orf19.5772.

Phylogenomic databases

eggNOGiNOG296897.
InParanoidiQ5A8H7.
OrthoDBiEOG7PP5JH.

Family and domain databases

InterProiIPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
[Graphical view]
PANTHERiPTHR23227. PTHR23227. 1 hit.
PfamiPF07572. BCNT. 1 hit.
[Graphical view]
PROSITEiPS51279. BCNT_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiSWC5_CANAL
AccessioniPrimary (citable) accession number: Q5A8H7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: January 7, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.