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Protein

SWR1-complex protein 5

Gene

SWC5

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).By similarity

GO - Biological processi

Keywordsi

Molecular functionActivator, Chromatin regulator
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
SWR1-complex protein 5
Gene namesi
Name:SWC5
Ordered Locus Names:CAALFM_C603950CA
ORF Names:CaO19.13194, CaO19.5772
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 6

Organism-specific databases

CGDiCAL0000185200. orf19.5772.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002125031 – 338SWR1-complex protein 5Add BLAST338

Proteomic databases

PRIDEiQ5A8H7.

Interactioni

Subunit structurei

Component of the SWR1 chromatin remodeling complex.By similarity

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini251 – 331BCNT-CPROSITE-ProRule annotationAdd BLAST81

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi160 – 183Gln-richAdd BLAST24

Sequence similaritiesi

Belongs to the SWC5 family.Curated

Phylogenomic databases

InParanoidiQ5A8H7.
OrthoDBiEOG092C4M55.

Family and domain databases

InterProiView protein in InterPro
IPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
PANTHERiPTHR23227. PTHR23227. 1 hit.
PfamiView protein in Pfam
PF07572. BCNT. 1 hit.
PROSITEiView protein in PROSITE
PS51279. BCNT_C. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5A8H7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQNIDKST EHSAGENALS EKNHTIESNK NNIDSEEDDE EDEDYDPEKK
60 70 80 90 100
NEAENEGGVS SDEEEDNDQY KDGKTSKIPD YSTIESSTSQ VKTRSQRLHE
110 120 130 140 150
KLSNQSRFIG NFEVDSKTGL VKDQSNIDVN SIFENLKNGS PSIDNSEELN
160 170 180 190 200
IDSEKTANSQ QQQKQQSNIE ENELQGPKQI KIQINYTFAG KLITETKYVD
210 220 230 240 250
ENSQEAKAYL NSTSNISSSN SNEDIPYRRS QVKVIRTDPV TNETKELRIK
260 270 280 290 300
LKRPSLIDRF LSINGNSKKM KLSTLEKSRL DWASFVDKRN INEELKIHNK
310 320 330
AGYLDKQDFI NRMNSKRDDL YLQAKEKEKI RKQQLLQK
Length:338
Mass (Da):38,842
Last modified:April 12, 2017 - v2
Checksum:iFD54586504966CFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017628 Genomic DNA. Translation: AOW30321.1.
RefSeqiXP_718107.2. XM_713014.2.

Genome annotation databases

EnsemblFungiiEAK99100; EAK99100; CaO19.13194.
EAK99175; EAK99175; CaO19.5772.
GeneIDi3640268.
KEGGical:CAALFM_C603950CA.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017628 Genomic DNA. Translation: AOW30321.1.
RefSeqiXP_718107.2. XM_713014.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5A8H7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAK99100; EAK99100; CaO19.13194.
EAK99175; EAK99175; CaO19.5772.
GeneIDi3640268.
KEGGical:CAALFM_C603950CA.

Organism-specific databases

CGDiCAL0000185200. orf19.5772.

Phylogenomic databases

InParanoidiQ5A8H7.
OrthoDBiEOG092C4M55.

Family and domain databases

InterProiView protein in InterPro
IPR011421. BCNT-C.
IPR027124. Swc5/CFDP.
PANTHERiPTHR23227. PTHR23227. 1 hit.
PfamiView protein in Pfam
PF07572. BCNT. 1 hit.
PROSITEiView protein in PROSITE
PS51279. BCNT_C. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSWC5_CANAL
AccessioniPrimary (citable) accession number: Q5A8H7
Secondary accession number(s): A0A1D8PQA7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 12, 2017
Last modified: May 10, 2017
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.