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Q5A6Q7

- EAF7_CANAL

UniProt

Q5A6Q7 - EAF7_CANAL

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Protein
Chromatin modification-related protein EAF7
Gene
EAF7, CaO19.497, CaO19.8127
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair By similarity.

GO - Biological processi

  1. DNA repair Source: UniProtKB-KW
  2. histone H4 acetylation Source: CGD
  3. regulation of transcription, DNA-templated Source: UniProtKB-KW
  4. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator

Keywords - Biological processi

DNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Chromatin modification-related protein EAF7
Gene namesi
Name:EAF7
ORF Names:CaO19.497, CaO19.8127
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0005877. orf19.497.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. NuA4 histone acetyltransferase complex Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Chromatin modification-related protein EAF7
PRO_0000215878Add
BLAST

Interactioni

Subunit structurei

Component of the NuA4 histone acetyltransferase complex By similarity.

Protein-protein interaction databases

STRINGi5476.CAL0005877.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi239 – 31880Glu-rich
Add
BLAST

Sequence similaritiesi

Belongs to the EAF7 family.

Phylogenomic databases

eggNOGiNOG279588.
KOiK11399.
OrthoDBiEOG76QFWQ.

Family and domain databases

InterProiIPR012423. Eaf7/MRGBP.
[Graphical view]
PfamiPF07904. Eaf7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5A6Q7-1 [UniParc]FASTAAdd to Basket

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MATLDENNPS KQTHRHWSIE NEIKLFSLLC DYKPAGKNKQ HNIKIIINNI    50
NESLDSKEEP FSEYDVWNKL RSLYDLEKID QIEELSTENT STEETTNQVS 100
SGSANITKDT KNAKTTLDAK EPIQDKKEMD KEKSESSSLS TPEPPQRRTR 150
SARDTTKSKR NLRDTPKEKS QYNDEEITSG GAEKSKVEVS STSDHTDDQS 200
PTPGSTKKGL DEQTNDDMSD IEDVDKDKGD ETIAKIKKEN TSEQEEDKNK 250
KQTEEEAEEE EEEGDHVSGD ERESKNKDTS EDEDGEDNED QDEDDVEVIE 300
DSHTDKENES SSEESSPEPM TKRTRQRTRS THEKTEHTSP NIKKRTRQSV 350
KFDDKPAEPS DTGSRKRRAP PGSVSPPHPP KTRRRTRSVT HEIEEEDAST 400
QSADDAEPEI IKVETRHTTR RSSRISMEPS SSTPNVRVRR SSRKR 445
Length:445
Mass (Da):50,718
Last modified:April 26, 2005 - v1
Checksum:iD5281A9D3D2FB08C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000055 Genomic DNA. Translation: EAK98391.1.
AACQ01000054 Genomic DNA. Translation: EAK98483.1.
RefSeqiXP_717360.1. XM_712267.1.
XP_717449.1. XM_712356.1.

Genome annotation databases

GeneIDi3640908.
3640973.
KEGGical:CaO19.497.
cal:CaO19.8127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000055 Genomic DNA. Translation: EAK98391.1 .
AACQ01000054 Genomic DNA. Translation: EAK98483.1 .
RefSeqi XP_717360.1. XM_712267.1.
XP_717449.1. XM_712356.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0005877.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3640908.
3640973.
KEGGi cal:CaO19.497.
cal:CaO19.8127.

Organism-specific databases

CGDi CAL0005877. orf19.497.

Phylogenomic databases

eggNOGi NOG279588.
KOi K11399.
OrthoDBi EOG76QFWQ.

Family and domain databases

InterProi IPR012423. Eaf7/MRGBP.
[Graphical view ]
Pfami PF07904. Eaf7. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiEAF7_CANAL
AccessioniPrimary (citable) accession number: Q5A6Q7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi