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Protein

Chromatin modification-related protein EAF7

Gene

EAF7

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).By similarity

GO - Biological processi

Keywordsi

Molecular functionChromatin regulator
Biological processDNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Chromatin modification-related protein EAF7
Gene namesi
Name:EAF7
Ordered Locus Names:CAALFM_CR04130CA
ORF Names:CaO19.497, CaO19.8127
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome R

Organism-specific databases

CGDiCAL0000190105 EAF7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002158781 – 445Chromatin modification-related protein EAF7Add BLAST445

Proteomic databases

PRIDEiQ5A6Q7

Interactioni

Subunit structurei

Component of the NuA4 histone acetyltransferase complex.By similarity

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi239 – 318Glu-richAdd BLAST80

Sequence similaritiesi

Belongs to the EAF7 family.Curated

Phylogenomic databases

InParanoidiQ5A6Q7
KOiK11399
OMAiRTRSETH
OrthoDBiEOG092C1KQF

Family and domain databases

InterProiView protein in InterPro
IPR012423 Eaf7/MRGBP
PANTHERiPTHR13581 PTHR13581, 1 hit
PfamiView protein in Pfam
PF07904 Eaf7, 1 hit

Sequencei

Sequence statusi: Complete.

Q5A6Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLDENNPS KQTHRHWSIE NEIKLFSLLC DYKPAGKNKQ HNIKIIINNI
60 70 80 90 100
NESLDSKEEP FSEYDVWNKL RSLYDLEKID QIEELSTENT STEETTNQVS
110 120 130 140 150
SGSANITKDT KNAKTTLDAK EPIQDKKEMD KEKSESSSLS TPEPPQRRTR
160 170 180 190 200
SARDTTKSKR NLRDTPKEKS QYNDEEITSG GAEKSKVEVS STSDHTDDQS
210 220 230 240 250
PTPGSTKKGL DEQTNDDMSD IEDVDKDKGD ETIAKIKKEN TSEQEEDKNK
260 270 280 290 300
KQTEEEAEEE EEEGDHVSGD ERESKNKDTS EDEDGEDNED QDEDDVEVIE
310 320 330 340 350
DSHTDKENES SSEESSPEPM TKRTRQRTRS THEKTEHTSP NIKKRTRQSV
360 370 380 390 400
KFDDKPAEPS DTGSRKRRAP PGSVSPPHPP KTRRRTRSVT HEIEEEDAST
410 420 430 440
QSADDAEPEI IKVETRHTTR RSSRISMEPS SSTPNVRVRR SSRKR
Length:445
Mass (Da):50,718
Last modified:April 26, 2005 - v1
Checksum:iD5281A9D3D2FB08C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017630 Genomic DNA Translation: AOW31151.1
RefSeqiXP_717360.1, XM_712267.2

Genome annotation databases

EnsemblFungiiAOW31151; AOW31151; CAALFM_CR04130CA
GeneIDi3640973
KEGGical:CAALFM_CR04130CA

Similar proteinsi

Entry informationi

Entry nameiEAF7_CANAL
AccessioniPrimary (citable) accession number: Q5A6Q7
Secondary accession number(s): A0A1D8PSN4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: March 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health