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Q5A6Q7

- EAF7_CANAL

UniProt

Q5A6Q7 - EAF7_CANAL

Protein

Chromatin modification-related protein EAF7

Gene

EAF7

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair By similarity.By similarity

    GO - Biological processi

    1. DNA repair Source: UniProtKB-KW
    2. histone H4 acetylation Source: CGD
    3. regulation of transcription, DNA-templated Source: UniProtKB-KW
    4. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulator

    Keywords - Biological processi

    DNA damage, DNA repair, Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chromatin modification-related protein EAF7
    Gene namesi
    Name:EAF7
    ORF Names:CaO19.497, CaO19.8127
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0005877. orf19.497.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. NuA4 histone acetyltransferase complex Source: CGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 445445Chromatin modification-related protein EAF7PRO_0000215878Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the NuA4 histone acetyltransferase complex.By similarity

    Protein-protein interaction databases

    STRINGi5476.CAL0005877.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi239 – 31880Glu-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the EAF7 family.Curated

    Phylogenomic databases

    eggNOGiNOG279588.
    KOiK11399.
    OrthoDBiEOG76QFWQ.

    Family and domain databases

    InterProiIPR012423. Eaf7/MRGBP.
    [Graphical view]
    PfamiPF07904. Eaf7. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5A6Q7-1 [UniParc]FASTAAdd to Basket

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    MATLDENNPS KQTHRHWSIE NEIKLFSLLC DYKPAGKNKQ HNIKIIINNI    50
    NESLDSKEEP FSEYDVWNKL RSLYDLEKID QIEELSTENT STEETTNQVS 100
    SGSANITKDT KNAKTTLDAK EPIQDKKEMD KEKSESSSLS TPEPPQRRTR 150
    SARDTTKSKR NLRDTPKEKS QYNDEEITSG GAEKSKVEVS STSDHTDDQS 200
    PTPGSTKKGL DEQTNDDMSD IEDVDKDKGD ETIAKIKKEN TSEQEEDKNK 250
    KQTEEEAEEE EEEGDHVSGD ERESKNKDTS EDEDGEDNED QDEDDVEVIE 300
    DSHTDKENES SSEESSPEPM TKRTRQRTRS THEKTEHTSP NIKKRTRQSV 350
    KFDDKPAEPS DTGSRKRRAP PGSVSPPHPP KTRRRTRSVT HEIEEEDAST 400
    QSADDAEPEI IKVETRHTTR RSSRISMEPS SSTPNVRVRR SSRKR 445
    Length:445
    Mass (Da):50,718
    Last modified:April 26, 2005 - v1
    Checksum:iD5281A9D3D2FB08C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000055 Genomic DNA. Translation: EAK98391.1.
    AACQ01000054 Genomic DNA. Translation: EAK98483.1.
    RefSeqiXP_717360.1. XM_712267.1.
    XP_717449.1. XM_712356.1.

    Genome annotation databases

    GeneIDi3640908.
    3640973.
    KEGGical:CaO19.497.
    cal:CaO19.8127.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000055 Genomic DNA. Translation: EAK98391.1 .
    AACQ01000054 Genomic DNA. Translation: EAK98483.1 .
    RefSeqi XP_717360.1. XM_712267.1.
    XP_717449.1. XM_712356.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0005877.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3640908.
    3640973.
    KEGGi cal:CaO19.497.
    cal:CaO19.8127.

    Organism-specific databases

    CGDi CAL0005877. orf19.497.

    Phylogenomic databases

    eggNOGi NOG279588.
    KOi K11399.
    OrthoDBi EOG76QFWQ.

    Family and domain databases

    InterProi IPR012423. Eaf7/MRGBP.
    [Graphical view ]
    Pfami PF07904. Eaf7. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiEAF7_CANAL
    AccessioniPrimary (citable) accession number: Q5A6Q7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 20, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3