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Protein

Chromatin modification-related protein EAF7

Gene

EAF7

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator

Keywords - Biological processi

DNA damage, DNA repair, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Chromatin modification-related protein EAF7
Gene namesi
Name:EAF7
ORF Names:CaO19.497, CaO19.8127
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000000559 Componenti: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0005877. orf19.497.

Subcellular locationi

GO - Cellular componenti

  • NuA4 histone acetyltransferase complex Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Chromatin modification-related protein EAF7PRO_0000215878Add
BLAST

Interactioni

Subunit structurei

Component of the NuA4 histone acetyltransferase complex.By similarity

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi239 – 31880Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the EAF7 family.Curated

Phylogenomic databases

eggNOGiNOG279588.
InParanoidiQ5A6Q7.
KOiK11399.
OrthoDBiEOG76QFWQ.

Family and domain databases

InterProiIPR012423. Eaf7/MRGBP.
[Graphical view]
PfamiPF07904. Eaf7. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5A6Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATLDENNPS KQTHRHWSIE NEIKLFSLLC DYKPAGKNKQ HNIKIIINNI
60 70 80 90 100
NESLDSKEEP FSEYDVWNKL RSLYDLEKID QIEELSTENT STEETTNQVS
110 120 130 140 150
SGSANITKDT KNAKTTLDAK EPIQDKKEMD KEKSESSSLS TPEPPQRRTR
160 170 180 190 200
SARDTTKSKR NLRDTPKEKS QYNDEEITSG GAEKSKVEVS STSDHTDDQS
210 220 230 240 250
PTPGSTKKGL DEQTNDDMSD IEDVDKDKGD ETIAKIKKEN TSEQEEDKNK
260 270 280 290 300
KQTEEEAEEE EEEGDHVSGD ERESKNKDTS EDEDGEDNED QDEDDVEVIE
310 320 330 340 350
DSHTDKENES SSEESSPEPM TKRTRQRTRS THEKTEHTSP NIKKRTRQSV
360 370 380 390 400
KFDDKPAEPS DTGSRKRRAP PGSVSPPHPP KTRRRTRSVT HEIEEEDAST
410 420 430 440
QSADDAEPEI IKVETRHTTR RSSRISMEPS SSTPNVRVRR SSRKR
Length:445
Mass (Da):50,718
Last modified:April 26, 2005 - v1
Checksum:iD5281A9D3D2FB08C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000055 Genomic DNA. Translation: EAK98391.1.
AACQ01000054 Genomic DNA. Translation: EAK98483.1.
RefSeqiXP_717360.1. XM_712267.1.
XP_717449.1. XM_712356.1.

Genome annotation databases

GeneIDi3640908.
3640973.
KEGGical:CaO19.497.
cal:CaO19.8127.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACQ01000055 Genomic DNA. Translation: EAK98391.1.
AACQ01000054 Genomic DNA. Translation: EAK98483.1.
RefSeqiXP_717360.1. XM_712267.1.
XP_717449.1. XM_712356.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3640908.
3640973.
KEGGical:CaO19.497.
cal:CaO19.8127.

Organism-specific databases

CGDiCAL0005877. orf19.497.

Phylogenomic databases

eggNOGiNOG279588.
InParanoidiQ5A6Q7.
KOiK11399.
OrthoDBiEOG76QFWQ.

Family and domain databases

InterProiIPR012423. Eaf7/MRGBP.
[Graphical view]
PfamiPF07904. Eaf7. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiEAF7_CANAL
AccessioniPrimary (citable) accession number: Q5A6Q7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: April 26, 2005
Last modified: June 24, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.