Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5A6N8 (RFT1_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Oligosaccharide translocation protein RFT1
Gene names
Name:RFT1
ORF Names:CaO19.516, CaO19.8147
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida ›

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane By similarity.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the RFT1 family.

Ontologies

Keywords
   Biological processSugar transport
Transport
   Cellular componentEndoplasmic reticulum
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbohydrate transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentendoplasmic reticulum membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

integral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionlipid transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Oligosaccharide translocation protein RFT1
PRO_0000212415

Regions

Transmembrane25 – 4521Helical; Potential
Transmembrane49 – 6921Helical; Potential
Transmembrane95 – 11521Helical; Potential
Transmembrane136 – 15621Helical; Potential
Transmembrane168 – 18821Helical; Potential
Transmembrane199 – 21921Helical; Potential
Transmembrane350 – 37021Helical; Potential
Transmembrane398 – 41821Helical; Potential
Transmembrane429 – 44921Helical; Potential
Transmembrane452 – 46918Helical; Potential
Transmembrane493 – 51321Helical; Potential
Transmembrane519 – 53921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5A6N8 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 509B006373F52252

FASTA56164,386
        10         20         30         40         50         60 
MSVSSSKQPG NDANDANSSV KGVSHLIIVQ IIAKLLTFVL NQLIIRYLSP SIIGVTTYLE 

        70         80         90        100        110        120 
FICSTILFFS RESIRLSVQR VRNNSDNKDY VAQKVVNFGI LAIAFAFPIF MVIGYWQLNY 

       130        140        150        160        170        180 
SSVMDKLFVS PFYKPVIVLF VASVILELLV EPIYCLYQFQ LDFGKRSKFE GSAIFVKCIV 

       190        200        210        220        230        240 
SVLSILLARQ YFVDQKFEGV AICAFALAQF SYSLTLFACY LMSFRFEFQN NKINYNLVKL 

       250        260        270        280        290        300 
KDENAREFYF EQDTLTIVKG FFVQMIFKQF LTEGDKLLIS HLCTIEEQGM YAVMANYGSI 

       310        320        330        340        350        360 
IARLLFQPLE ESTRLMFTKL LNENTRSQGD EKPQKSESHK CMQTFNYLKL ISIFYFNLSL 

       370        380        390        400        410        420 
IILFAGVTSG PYLLKLLMGG RASNWESTDI FKLFPQYVVY LPFLAFNGIL EALFSSMATN 

       430        440        450        460        470        480 
SDLKNFSKFM TLITILVLIF SYLLIDVLNL RISGLILANV FNMSSRIGYC YFKISKFYSK 

       490        500        510        520        530        540 
ENVKVSFVDI VRYSCPSILI TSIIWIIQLF IIGKNTTNFV QLILNACFSF VLVIILMVME 

       550        560 
RKNSKKPFEK VTNKFMKPKL D

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AACQ01000055 Genomic DNA. Translation: EAK98410.1.
AACQ01000054 Genomic DNA. Translation: EAK98503.1.
RefSeqXP_717379.1. XM_712286.1.
XP_717469.1. XM_712376.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING5476.CAL0000084.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3640852.
3640993.
KEGGcal:CaO19.516.
cal:CaO19.8147.

Organism-specific databases

CGDCAL0000084. orf19.516.

Phylogenomic databases

eggNOGNOG267200.
KOK06316.

Family and domain databases

InterProIPR007594. RFT1.
[Graphical view]
PANTHERPTHR13117. PTHR13117. 1 hit.
PfamPF04506. Rft-1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRFT1_CANAL
AccessionPrimary (citable) accession number: Q5A6N8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: April 26, 2005
Last modified: April 3, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents