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Protein

Autophagy-related protein 22

Gene

ATG22

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be required for lysis of autophagic vesicles after delivery to the vacuole.By similarity

GO - Biological processi

Keywordsi

Biological processAutophagy, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Autophagy-related protein 22
Gene namesi
Name:ATG22
Ordered Locus Names:CAALFM_CR04610CA
ORF Names:CaO19.552, CaO19.8187
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome R

Organism-specific databases

CGDiCAL0000198702. orf19.552.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei108 – 128HelicalSequence analysisAdd BLAST21
Transmembranei137 – 157HelicalSequence analysisAdd BLAST21
Transmembranei164 – 184HelicalSequence analysisAdd BLAST21
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Transmembranei244 – 264HelicalSequence analysisAdd BLAST21
Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Transmembranei368 – 388HelicalSequence analysisAdd BLAST21
Transmembranei438 – 458HelicalSequence analysisAdd BLAST21
Transmembranei467 – 487HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002076191 – 500Autophagy-related protein 22Add BLAST500

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi14N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ5A6K2.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATG22 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ5A6K2.
OrthoDBiEOG092C2ZD0.

Family and domain databases

InterProiView protein in InterPro
IPR024671. Atg22-like.
IPR020846. MFS_dom.
PfamiView protein in Pfam
PF11700. ATG22. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5A6K2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVNHNHISN TGVNDSEDIL EAQDEISIDN NKNQENIWNK KSIFHTWLLL
60 70 80 90 100
CYSTGPVASM SRTYIPASIQ SIAKNVGKTK MNQPCGTQGN DCYVKFGFMT
110 120 130 140 150
VHHTSYVLYL RAVSTAIEGV VAIFLMGIAD YSNYRKSFLI FSILVYGFLA
160 170 180 190 200
LPFIGLTNND YQTLVLASIL YSLLIIDDSI YQILEGSYIP LFMRADKKNP
210 220 230 240 250
MQRGSVVAVL GLFLGNLGGI TALVIGIIIS YLSGTPESKG YHNFLLAITI
260 270 280 290 300
AGCLTIGLSL FSALYIPNVQ GKQRIDNFLV LPFKRFFNLL KDIQKYPMAF
310 320 330 340 350
LYCISWVIWN VSFNNFMSMF LLLFRSTLGL GNSDAEYTVY TFMSYICSSW
360 370 380 390 400
GSLVWMFLYQ KWNSNIKYWG YSFLSVSLLA NFWGCLGIHK LTPLGYQNRW
410 420 430 440 450
EFWVFEVFYS ATSSAMRSLN RCVYSSLLPE GNEAQYFGLE VTLGIASGWI
460 470 480 490 500
GGLVNAVIQD RTNDDRFPFL PNMFLVVVSL IVYYYVDLQK GKNDVNNGNS
Length:500
Mass (Da):56,529
Last modified:April 12, 2017 - v2
Checksum:iC17DD6EB2F2AD93F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017630 Genomic DNA. Translation: AOW31197.1.
RefSeqiXP_717415.2. XM_712322.2.

Genome annotation databases

GeneIDi3640951.
KEGGical:CAALFM_CR04610CA.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiATG22_CANAL
AccessioniPrimary (citable) accession number: Q5A6K2
Secondary accession number(s): A0A1D8PSS7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: April 12, 2017
Last modified: June 7, 2017
This is version 57 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families