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Q5A6K2

- ATG22_CANAL

UniProt

Q5A6K2 - ATG22_CANAL

Protein

Autophagy-related protein 22

Gene

ATG22

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
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    Functioni

    May be required for lysis of autophagic vesicles after delivery to the vacuole.By similarity

    GO - Biological processi

    1. autophagy Source: UniProtKB-KW
    2. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Autophagy, Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Autophagy-related protein 22
    Gene namesi
    Name:ATG22
    ORF Names:CaO19.552, CaO19.8187
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000232. orf19.552.

    Subcellular locationi

    Vacuole membrane By similarity; Multi-pass membrane protein By similarity
    Note: Vacuole and punctate structures.By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. vacuolar membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Vacuole

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 500500Autophagy-related protein 22PRO_0000207619Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi10 – 101N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi14 – 141N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei108 – 12821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei137 – 15721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei164 – 18421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei209 – 22921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei244 – 26421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei304 – 32421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei339 – 35921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei368 – 38821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei438 – 45821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei467 – 48721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATG22 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG146046.
    OrthoDBiEOG7F7WJP.

    Family and domain databases

    InterProiIPR024671. Atg22-like.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view]
    PfamiPF11700. ATG22. 1 hit.
    [Graphical view]
    SUPFAMiSSF103473. SSF103473. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5A6K2-1 [UniParc]FASTAAdd to Basket

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    MKVNHNHISN TSVNNSEDVL EAQDEISNDN NKNQESIWNK KSIFHTWLLL    50
    CYSTGPVASM SRTYIPASIQ SIAKNVGKTK MNQPCGTQGN DCYVKFGFMT 100
    VHHTSYVLYL RAVSTAIEGV VAIFLMGIAD YSNYRKSFLI FSILVYGFLA 150
    LPFIGLTNND YQTLVLASIL YSLLIIDDSI YQILEGSYIP LFMRADKKNP 200
    MQRGSVVAVL GLFLGNLGGI TALVIGIIIS YLSGTPESKG YHNFLLAITI 250
    AGCLTIGLSL FSALYIPNVQ GKQRIDNFLV LPFKRFFNLL KDIQKYPMAF 300
    LYCISWVIWN VSFNNFMSMF LLLFRSTLGL GNSDAEYTVY TFMSYICSSW 350
    GSLLWMFLYQ KWNSNIKYWG YSFLSVSLLA NFWGCLGIHK LTPLGYQNRW 400
    EFWVFEVFYS ATSSAMRSLN RCVYSSLLPE GNEAQYFGLE VTLGIASGWI 450
    GGLVNAVIQD RTNDDRFPFL PNMFLVVVSL IVYYYVDLQK GKNDVNNGNS 500
    Length:500
    Mass (Da):56,532
    Last modified:April 26, 2005 - v1
    Checksum:i83F4934EBB6958FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000055 Genomic DNA. Translation: EAK98446.1.
    AACQ01000054 Genomic DNA. Translation: EAK98543.1.
    RefSeqiXP_717415.1. XM_712322.1.
    XP_717509.1. XM_712416.1.

    Genome annotation databases

    GeneIDi3640918.
    3640951.
    KEGGical:CaO19.552.
    cal:CaO19.8187.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000055 Genomic DNA. Translation: EAK98446.1 .
    AACQ01000054 Genomic DNA. Translation: EAK98543.1 .
    RefSeqi XP_717415.1. XM_712322.1.
    XP_717509.1. XM_712416.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3640918.
    3640951.
    KEGGi cal:CaO19.552.
    cal:CaO19.8187.

    Organism-specific databases

    CGDi CAL0000232. orf19.552.

    Phylogenomic databases

    eggNOGi NOG146046.
    OrthoDBi EOG7F7WJP.

    Family and domain databases

    InterProi IPR024671. Atg22-like.
    IPR016196. MFS_dom_general_subst_transpt.
    [Graphical view ]
    Pfami PF11700. ATG22. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103473. SSF103473. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiATG22_CANAL
    AccessioniPrimary (citable) accession number: Q5A6K2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3