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Q5A6K2 (ATG22_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 13, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Autophagy-related protein 22
Gene names
Name:ATG22
ORF Names:CaO19.552, CaO19.8187
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida ›

Protein attributes

Sequence length500 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May be required for lysis of autophagic vesicles after delivery to the vacuole By similarity.

Subcellular location

Vacuole membrane; Multi-pass membrane protein By similarity. Note: Vacuole and punctate structures By similarity.

Sequence similarities

Belongs to the ATG22 family.

Ontologies

Keywords
   Biological processAutophagy
Protein transport
Transport
   Cellular componentMembrane
Vacuole
   DomainTransmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processautophagy

Inferred from electronic annotation. Source: UniProtKB-KW

protein transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

vacuolar membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 500500Autophagy-related protein 22
PRO_0000207619

Regions

Transmembrane108 – 12821Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane164 – 18421Helical; Potential
Transmembrane209 – 22921Helical; Potential
Transmembrane244 – 26421Helical; Potential
Transmembrane304 – 32421Helical; Potential
Transmembrane339 – 35921Helical; Potential
Transmembrane368 – 38821Helical; Potential
Transmembrane438 – 45821Helical; Potential
Transmembrane467 – 48721Helical; Potential

Amino acid modifications

Glycosylation101N-linked (GlcNAc...) Potential
Glycosylation141N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q5A6K2 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 83F4934EBB6958FC

FASTA50056,532
        10         20         30         40         50         60 
MKVNHNHISN TSVNNSEDVL EAQDEISNDN NKNQESIWNK KSIFHTWLLL CYSTGPVASM 

        70         80         90        100        110        120 
SRTYIPASIQ SIAKNVGKTK MNQPCGTQGN DCYVKFGFMT VHHTSYVLYL RAVSTAIEGV 

       130        140        150        160        170        180 
VAIFLMGIAD YSNYRKSFLI FSILVYGFLA LPFIGLTNND YQTLVLASIL YSLLIIDDSI 

       190        200        210        220        230        240 
YQILEGSYIP LFMRADKKNP MQRGSVVAVL GLFLGNLGGI TALVIGIIIS YLSGTPESKG 

       250        260        270        280        290        300 
YHNFLLAITI AGCLTIGLSL FSALYIPNVQ GKQRIDNFLV LPFKRFFNLL KDIQKYPMAF 

       310        320        330        340        350        360 
LYCISWVIWN VSFNNFMSMF LLLFRSTLGL GNSDAEYTVY TFMSYICSSW GSLLWMFLYQ 

       370        380        390        400        410        420 
KWNSNIKYWG YSFLSVSLLA NFWGCLGIHK LTPLGYQNRW EFWVFEVFYS ATSSAMRSLN 

       430        440        450        460        470        480 
RCVYSSLLPE GNEAQYFGLE VTLGIASGWI GGLVNAVIQD RTNDDRFPFL PNMFLVVVSL 

       490        500 
IVYYYVDLQK GKNDVNNGNS

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AACQ01000055 Genomic DNA. Translation: EAK98446.1.
AACQ01000054 Genomic DNA. Translation: EAK98543.1.
RefSeqXP_717415.1. XM_712322.1.
XP_717509.1. XM_712416.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3640918.
3640951.
KEGGcal:CaO19.552.
cal:CaO19.8187.

Organism-specific databases

CGDCAL0000232. orf19.552.

Phylogenomic databases

eggNOGNOG146046.

Family and domain databases

InterProIPR024671. Atg22-like.
IPR016196. MFS_dom_general_subst_transpt.
[Graphical view]
PfamPF11700. ATG22. 1 hit.
[Graphical view]
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
ProtoNetSearch...

Entry information

Entry nameATG22_CANAL
AccessionPrimary (citable) accession number: Q5A6K2
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: April 26, 2005
Last modified: June 13, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

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