Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q5A4J4

- PBN1_CANAL

UniProt

Q5A4J4 - PBN1_CANAL

Protein

Protein PBN1

Gene

PBN1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (26 Apr 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 By similarity.By similarity

    Pathwayi

    GO - Biological processi

    1. GPI anchor biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Biological processi

    GPI-anchor biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00196.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein PBN1
    Gene namesi
    Name:PBN1
    ORF Names:CaO19.10951, CaO19.3447
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0067292. orf19.10951.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 489489Protein PBN1PRO_0000246301Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi22 – 221N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi52 – 521N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi180 – 1801N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi212 – 2121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi272 – 2721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi296 – 2961N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi353 – 3531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi366 – 3661N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi457 – 4571N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0004996.

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 459459LumenalSequence AnalysisAdd
    BLAST
    Topological domaini481 – 4899CytoplasmicSequence Analysis

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei460 – 48021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PIGX family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG86258.
    OrthoDBiEOG783N68.

    Family and domain databases

    InterProiIPR013233. PIG-X/PBN1.
    [Graphical view]
    PfamiPF08320. PIG-X. 1 hit.
    [Graphical view]
    SMARTiSM00780. PIG-X. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5A4J4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRQRTTIYNP YSSHDGIITN LNRTNFQLSS IPNHLFTIEN KYTITITTTQ    50
    PNKSSLYSAI KELRIQTKFN NNESGIPIFS FHYKPGLNIY AVPQSNVDKL 100
    EFWQQVEQLI MELLGIKLSS QQWIANVNSF YYHDIQPQPL LNLNLNLNLK 150
    EGWKFNLHPK SNYDYIYNQD KIIIRELLTN VSEIEFNLES GIYKEIGLFL 200
    IDDKISTNDD LNLSGIRVIL DEDSNTNNKE ESIHKTMFHI KPRHRSFDDS 250
    TTITTTKIIP QGLHPILSTE LNTTTIVMPT DFDVEECKFY YYLNLNKSLI 300
    FDQFQNIPIG SQLIINNGNK NLELPEYKIN QWGNELLFEF EFDNDNDIPH 350
    HINLTVHSRY QLPQNNHSHS HSQISNVLNS LPNIFMGCNV KEGNLLDKSP 400
    FDTKRDVKIG GNYEIYFTED TVFYHLQNSD NSDNSGSSTL LEINIPHGKT 450
    TFDRVNNITS LGLLIGVLMI LYAISIRVFM STTSKTKRD 489
    Length:489
    Mass (Da):56,565
    Last modified:April 26, 2005 - v1
    Checksum:i12B00A79A0BC4EEC
    GO

    Sequence cautioni

    The sequence EAK97766.1 differs from that shown. Reason: Erroneous gene model prediction.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti46 – 461I → T in allele CaO19.3447.
    Natural varianti84 – 841K → E in allele CaO19.3447.
    Natural varianti141 – 1466Missing in allele CaO19.3447.
    Natural varianti203 – 2031D → E in allele CaO19.3447.
    Natural varianti278 – 2781M → I in allele CaO19.3447.
    Natural varianti386 – 3861M → I in allele CaO19.3447.
    Natural varianti433 – 4331D → G in allele CaO19.3447.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000064 Genomic DNA. Translation: EAK97766.1. Sequence problems.
    AACQ01000065 Genomic DNA. Translation: EAK97703.1.
    RefSeqiXP_716695.1. XM_711602.1.
    XP_716754.1. XM_711661.1.

    Genome annotation databases

    GeneIDi3641607.
    3641704.
    KEGGical:CaO19.10951.
    cal:CaO19.3447.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AACQ01000064 Genomic DNA. Translation: EAK97766.1 . Sequence problems.
    AACQ01000065 Genomic DNA. Translation: EAK97703.1 .
    RefSeqi XP_716695.1. XM_711602.1.
    XP_716754.1. XM_711661.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0004996.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3641607.
    3641704.
    KEGGi cal:CaO19.10951.
    cal:CaO19.3447.

    Organism-specific databases

    CGDi CAL0067292. orf19.10951.

    Phylogenomic databases

    eggNOGi NOG86258.
    OrthoDBi EOG783N68.

    Enzyme and pathway databases

    UniPathwayi UPA00196 .

    Family and domain databases

    InterProi IPR013233. PIG-X/PBN1.
    [Graphical view ]
    Pfami PF08320. PIG-X. 1 hit.
    [Graphical view ]
    SMARTi SM00780. PIG-X. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiPBN1_CANAL
    AccessioniPrimary (citable) accession number: Q5A4J4
    Secondary accession number(s): Q5A4Q8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2006
    Last sequence update: April 26, 2005
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3