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Q5A3Q0

- REXO4_CANAL

UniProt

Q5A3Q0 - REXO4_CANAL

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Protein
RNA exonuclease 4
Gene
REX4, CaO19.12687, CaO19.5220
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs By similarity.

GO - Molecular functioni

  1. exonuclease activity Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA exonuclease 4 (EC:3.1.-.-)
Gene namesi
Name:REX4
ORF Names:CaO19.12687, CaO19.5220
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0003518. orf19.5220.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 285285RNA exonuclease 4
PRO_0000131692Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5476.CAL0003518.

Structurei

3D structure databases

ProteinModelPortaliQ5A3Q0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini116 – 267152Exonuclease
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi47 – 8842Thr-rich
Add
BLAST

Sequence similaritiesi

Belongs to the REXO4 family.
Contains 1 exonuclease domain.

Phylogenomic databases

eggNOGiCOG0847.
KOiK18327.
OrthoDBiEOG751NQ2.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006055. Exonuclease.
IPR013520. Exonuclease_RNaseT/DNA_pol3.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF00929. RNase_T. 1 hit.
[Graphical view]
SMARTiSM00479. EXOIII. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5A3Q0-1 [UniParc]FASTAAdd to Basket

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MAKLSQNWKK LSSKIQDKPK NGSVKKPTLK GKISKKVKAS ISEKLSTTNN    50
TTTTTTTTTS TTDVVPIASS TKPTATPLEY TLWTQNHTIN VSHIPKTPKP 100
LPLSRNDSRK LDPGKYVAID CEFVGIGKDG EESALARISI INYYGVVLLD 150
TYVRPQERVT DWRTWVSGIQ SYHMQDAIDF KTAQLKTMEL INNKILVGHA 200
VNNDLDILFL SHPKSMIRDT CKFPKFREIA GGKSPSLKKL IKHFIQVDIQ 250
IGQHSSVEDA RATMLLFRLF KREIEQSMRN RNKRQ 285
Length:285
Mass (Da):32,210
Last modified:April 26, 2005 - v1
Checksum:iB861D7C31107CD6F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000070 Genomic DNA. Translation: EAK97357.1.
AACQ01000071 Genomic DNA. Translation: EAK97293.1.
RefSeqiXP_716289.1. XM_711196.1.
XP_716353.1. XM_711260.1.

Genome annotation databases

GeneIDi3641941.
3642012.
KEGGical:CaO19.12687.
cal:CaO19.5220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AACQ01000070 Genomic DNA. Translation: EAK97357.1 .
AACQ01000071 Genomic DNA. Translation: EAK97293.1 .
RefSeqi XP_716289.1. XM_711196.1.
XP_716353.1. XM_711260.1.

3D structure databases

ProteinModelPortali Q5A3Q0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5476.CAL0003518.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3641941.
3642012.
KEGGi cal:CaO19.12687.
cal:CaO19.5220.

Organism-specific databases

CGDi CAL0003518. orf19.5220.

Phylogenomic databases

eggNOGi COG0847.
KOi K18327.
OrthoDBi EOG751NQ2.

Family and domain databases

Gene3Di 3.30.420.10. 1 hit.
InterProi IPR006055. Exonuclease.
IPR013520. Exonuclease_RNaseT/DNA_pol3.
IPR012337. RNaseH-like_dom.
[Graphical view ]
Pfami PF00929. RNase_T. 1 hit.
[Graphical view ]
SMARTi SM00479. EXOIII. 1 hit.
[Graphical view ]
SUPFAMi SSF53098. SSF53098. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiREXO4_CANAL
AccessioniPrimary (citable) accession number: Q5A3Q0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: April 26, 2005
Last modified: September 3, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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