Reviewed, UniProtKB/Swiss-Prot Q5A1Z5 (ATG13_CANAL)

Names and origin

Protein names

Recommended name:
    Autophagy-related protein 13

Gene names

Name:	ATG13
ORF Names:	CaO19.2848, CaO19.10367

Organism

Candida albicans (Yeast)

Taxonomic identifier

5476 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida

Protein attributes

Sequence length	761 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in cytoplasm to vacuole transport (Cvt). Probably involved in the switching machinery regulating the conversion between the Cvt pathway and autophagy By similarity.
Subcellular location	Cytoplasm By similarity. Membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ATG13 fungi family.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Cytoplasm Membrane
Gene Ontology (GO)
Biological process	autophagy Inferred from electronic annotation. Source: UniProtKB-KW protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell extrinsic to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 761	761	Autophagy-related protein 13		PRO_0000157966
Regions
	Compositional bias	564 – 579	16	Gln-rich
	Compositional bias	696 – 704	9	Poly-Asp
Natural variations
	Natural variant	59	1	T → S in allele CaO19.10367.
	Natural variant	116	1	N → S in allele CaO19.10367.

Sequences

	Sequence		Length	Mass (Da)
	Q5A1Z5-1 [UniParc]. Last modified April 26, 2005. Version 1. Checksum: D219087EC3DDCFF0	FASTA	761	84,452
	10 20 30 40 50 60 MLSDFKQQQQ QKHHSHNPPN SHDDTQTKLQ VAKLTQVIQK FFTKAAQIIL ESRAYPETTT 70 80 90 100 110 120 PSLYPTKEES SKINKWFNLY MTNIPDSCKD DLKLWKGVDL TTIPPMIIET YIDLRNLPAD 130 140 150 160 170 180 QTLVLMDDEK HPWTVAKSRG KKQEVVLERW LIEFEPNTTD ATVMVEELPL SYKQAIVLFR 190 200 210 220 230 240 SIYGFTRLMP AFKVKKNLQN KLPLGNKILD GNQPISSKGR IGLSKPIINT RTNESHMTQK 250 260 270 280 290 300 YFQPVHTSLG TLKISVAYRM DSEFCLHENE ELLSSHFHKR DEEETKKKVS SSVSPLSSGT 310 320 330 340 350 360 SLKETSTSPR KSQPPIRIQP FKVGSMSTSP PVQSPSISQP GTAPIQNQPS VPSSSLERRV 370 380 390 400 410 420 SITSNKSTSN ASLAAFLRNA RSSTPSANNI PIINANPISG TSVPRSFSSS TGHEDSIFVN 430 440 450 460 470 480 PDSASNTPRF ASSFGSRASR RYSSTSIRQQ TPQSDLMGQT NSVDAALSGI DADDDISDFV 490 500 510 520 530 540 RMIDSKSDLR LGGGGGGGNS SVHNMSINES SYHGDALNKF QSLRSQYQQL SDSVSASLIL 550 560 570 580 590 600 QSRHSSRKSS LNSPAGSFDS HHHQHQQQQQ QQQNQQQSQS PHTNTTSSIH SHAHSYSHSR 610 620 630 640 650 660 MKDARPRSED HQQTKFSAAR RSSNISPTTA VPSSIGTPSS ISSRIPHVTT IISSSDVSST 670 680 690 700 710 720 GGNRTKSAAT TAIVSGMATS PSIYDYRSPR YQNVFDDDDE DDNDEEEGDR EGNQLHEGRN 730 740 750 760 STESSQNQSK RIMKHIKKDE EDSEDDEDLL FTMSDMNSRN F

References

[1]

"The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AACQ01000080 Genomic DNA. Translation: EAK96765.1. AACQ01000079 Genomic DNA. Translation: EAK96817.1.
RefSeq	XP_715779.1. XP_715830.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3642520. 3642586.
KEGG	cal:CaO19.10367. cal:CaO19.2848.
Organism-specific databases
CGD	CAL0005141. orf19.2848.
Phylogenomic databases
OrthoDB	EOG90031D
Family and domain databases
InterPro	IPR018731. Autophagy-rel_prot_13. [Graphical view]
Pfam	PF10033. ATG13. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATG13_CANAL

Accession

Primary (citable) accession number: Q5A1Z5
Secondary accession number(s): Q5A245

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	April 26, 2005
Last modified:	November 24, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)