Skip Header

Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q5A013 (NNT1_CANAL)

Last modified March 23, 2010. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Hide | Top

Names and originHide

Protein namesRecommended name:
Putative nicotinamide N-methyltransferase

EC=2.1.1.1
Gene names
Name:NNT1
ORF Names:CaO19.4375, CaO19.11853
OrganismCandida albicans (Yeast)
Taxonomic identifier5476 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycetaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
Hide | Top

Protein attributesHide

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology.
Hide | Top

General annotation (Comments)Hide

Function

Putative nicotinamide N-methyltransferase involved in rDNA silencing and in lifespan determination By similarity.

Catalytic activity

S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-methylnicotinamide.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the NNT1 family.

Hide | Top

OntologiesHide

Keywords
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionnicotinamide N-methyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...
Hide | Top

Sequence annotation (Features)Hide

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Putative nicotinamide N-methyltransferase
PRO_0000096891
Hide | Top

SequencesHide

Sequence LengthMass (Da)Tools
Q5A013-1 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 4C1EAFD9320AD296

FASTA26230,430
        10         20         30         40         50         60 
MSEDEISIEG DLFEEPEGFL PERPSSHFST YKRKIPNAEP QEITMKLVGH NPLYGHLLWN 

        70         80         90        100        110        120 
AGIYTADYLD KHSDTLVQGK KILELGAASA LPSLVCSLNH AKEVIVTDYP DPDLLSHMEY 

       130        140        150        160        170        180 
SFNDLKEKTK YELSPWKVKG YIWGHDLGEL LFDEPGRKLA EEEKFDLIIL SDLVFNHSEH 

       190        200        210        220        230        240 
HKLLDTCRQS LKRNGGKCLV VFSPHRPYLL QDDLSFFETA KQYQFKTEKI EMVTWKPMFE 

       250        260 
EDEETADIRA RVYAFFLIPE WE 

« Hide

Hide | Top

ReferencesHide

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314.
Hide | Top

Cross-referencesHide

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000090 Genomic DNA. Translation: EAK96118.1.
AACQ01000091 Genomic DNA. Translation: EAK96066.1.
RefSeqXP_715100.1.
XP_715151.1.

3D structure databases

SMRQ5A013. Positions 53-226.
ModBaseSearch...

Genome annotation databases

GeneID3643178.
3643242.
KEGGcal:CaO19.11853.
cal:CaO19.4375.

Organism-specific databases

CGDCAL0001114. orf19.4375.

Phylogenomic databases

OMAVVFSPHR.
OrthoDBEOG92BZS7.
PhylomeDBQ5A013.

Enzyme and pathway databases

BRENDA2.1.1.1. 1124.

Family and domain databases

InterProIPR019410. Methyltransferase-16_put.
[Graphical view]
PfamPF10294. Methyltransf_16. 1 hit.
[Graphical view]
ProtoNetSearch...
Hide | Top

Entry informationHide

Entry nameNNT1_CANAL
AccessionPrimary (citable) accession number: Q5A013
Entry history
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: April 26, 2005
Last modified: March 23, 2010
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)
Hide | Top

Relevant documentsHide

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents