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Q59ZX6 (UTP10_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
U3 small nucleolar RNA-associated protein 10
Gene names
Name:UTP10
ORF Names:CaO19.7215
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length1818 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis By similarity. UniProtKB P42945

Subunit structure

Component of the ribosomal small subunit (SSU) processome By similarity. UniProtKB P42945

Subcellular location

Nucleusnucleolus By similarity. Membrane; Single-pass membrane protein Potential UniProtKB P42945.

Sequence similarities

Belongs to the HEATR1/UTP10 family.

Contains 1 HEAT repeat.

Ontologies

Keywords
   Biological processRibosome biogenesis
rRNA processing
   Cellular componentMembrane
Nucleus
   DomainTransmembrane
Transmembrane helix
   Molecular functionRibonucleoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

nucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonucleoprotein complex

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 18181818U3 small nucleolar RNA-associated protein 10
PRO_0000308498

Regions

Transmembrane568 – 58821Helical; Potential
Repeat1778 – 181639HEAT

Sequences

Sequence LengthMass (Da)Tools
Q59ZX6 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: AFE1CCDB6EBAF902

FASTA1,818204,337
        10         20         30         40         50         60 
MSSLASQLQS INEKTASVAL DRKQRSKLHS RSLIFDPKQA ATQDYEYIYE IATEGLEDLC 

        70         80         90        100        110        120 
ELDSRFNKFK STLFSETSVN LDRNLQTKDV ISQLDKNIDA FLTLVGPYYG LTSSLKAVEW 

       130        140        150        160        170        180 
LVRRFHANIH NAELMILTAL PYFQHPVFVK VLNVIPKQNL PQIFEWLVGY KDQLKTPPAS 

       190        200        210        220        230        240 
SILKAFRNDF HFFNFYSKFL NDQIKNHTVY KEQLVFYLSN TVQLLASFSK NIEELNETHI 

       250        260        270        280        290        300 
PVVLETTALM LLPQQKPKYS SSINSDLKLT SYSIISVLSS IFPFSADILK SLTVSILEDE 

       310        320        330        340        350        360 
DALKGFTKPT LIVLSQLWKH FQGNLEVIEA FKNFKIGQHE LGVLDELKNE NYQLSTFIIL 

       370        380        390        400        410        420 
VFISTFPSNE SYKLLPFIDL SNKTVFEIIT KLVLQNSTTQ EDSIRSNLTK IAQSLTKSDP 

       430        440        450        460        470        480 
KLFQTTLESE NWKVDELELK LMSVLVESKN DEAEFDAGDE DNAVEDIEIV KTVDFTKLQS 

       490        500        510        520        530        540 
TAKSYFNTEY DEEFNLVLKE LKSVLSASDA KLHVSVILTF LQKVFSTPEV ALTFAFRVAL 

       550        560        570        580        590        600 
TPAVPLSIRL SAIKSIRIKI KNAANGKTDF YLLIPLILLA LFDNSKLIRS GFAQLLRLVI 

       610        620        630        640        650        660 
EIKTKLTTGA ALFLEREIYG SVSDKKYPTP HDSLFLCSLL SEDNVKDTVL DPSRVINILF 

       670        680        690        700        710        720 
DSIFKAKNGK SKPGKYFRSF IFTQWSLCSL PIVLKANAWK IVAQANKAGT DDRFFFLDGD 

       730        740        750        760        770        780 
IENYFSKRNV WIDQASIAGI AFFDNAEVSV VGLVGGVASN DKNSNTESEW LCRALENPSG 

       790        800        810        820        830        840 
NLQMTANNRV LETFDTFKPI ESRLKIVNKL VDILINDDIV EFDPMATLQE LNIDRNLFLQ 

       850        860        870        880        890        900 
ALTSVQIGDQ IPEQGIAKRR RRSSNSTKQA MVRDEINNMA SGHLKKLTFL LEILESSLRK 

       910        920        930        940        950        960 
KRNVAGPDLL KVLFKILTDL EYLGNDGNLP VLYAQETLAS CMLLNIVNLK SSSKEVKFDS 

       970        980        990       1000       1010       1020 
NSIRADLIVN SIRASPSPQV QNRLLLVISE LASLAPEVIL HSVMPIFTFM GAHTVRQDDE 

      1030       1040       1050       1060       1070       1080 
FSSSALQQTV AKVIPALASN GLSPVNNEIE FLLASFATAF PHVPRHRRVK LFVSLTKTLG 

      1090       1100       1110       1120       1130       1140 
CAESMHLILF LMGQQYANNV HKNKNGDSQS VVEFVHGYMK SFSAEEQLAG IVAFTKLWND 

      1150       1160       1170       1180       1190       1200 
IPLNQLEPGS EEFEVLNNRP VFGTTIATLG QSGLAVLRND LLQFLDETLS SENKHELSSL 

      1210       1220       1230       1240       1250       1260 
KTKMALVLID DEDSEVSKKE SVLDKFRAIT SFALASLDTF TNSHADIKLC STLYSLLGNL 

      1270       1280       1290       1300       1310       1320 
LDLLPLNYFI DSIVASLDVD TLSDSLSIKV ARNYAILASR KFETELNVAH CDQVVIESVI 

      1330       1340       1350       1360       1370       1380 
NNLLPILIKG IKKNVDVELQ QAYLDTFSTI VNKFGASGTE FASSDVSKVL IESLGIVTTD 

      1390       1400       1410       1420       1430       1440 
RGLLNEQPEV IIASINAITS IVNILGVKTL GLFPKVVPPA LKIWESTNSL GDKESAKLLQ 

      1450       1460       1470       1480       1490       1500 
GSVLVLLSCY IKKIPAFMST TLEAVLLTIL SSDLIDNHIR SSVLDLIVDH MDLAQVLKSL 

      1510       1520       1530       1540       1550       1560 
CNVWLTKKFY TNDNSGNIGL FLKTLQATIN KMEKKQATTQ ATLFMRWLIS AFEFRQYSED 

      1570       1580       1590       1600       1610       1620 
NDNKFDNNTI HRLESSFHGC AIAFVMKLND KSFRPLFANL VRWAVDGEGA TLKTNEVSRL 

      1630       1640       1650       1660       1670       1680 
LAFFRFFNKL QDELKSIITS YFSYLLDPTS ALLKRFSEGS LVATNLRRII LIGLTSSFKY 

      1690       1700       1710       1720       1730       1740 
DQDDYWSQQG RFDSICSPLL SQLSNIEDSI GKYLVKSVST FVTDVSSDEY NETLVHELIK 

      1750       1760       1770       1780       1790       1800 
YISNANENSA ATKIWSIRTL KTIFQKMGEQ WLSYLPTLVP YIAELLEDDD EEVEMEVRRG 

      1810 
LVRVIENVLG EPLDRYLS 

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References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000092 Genomic DNA. Translation: EAK95977.1.
RefSeqXP_715016.1. XM_709923.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5476.CAL0003770.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3643345.
KEGGcal:CaO19.7215.

Organism-specific databases

CGDCAL0003770. orf19.7215.

Phylogenomic databases

eggNOGNOG116525.
KOK14550.
OrthoDBEOG7KM623.

Family and domain databases

Gene3D1.25.10.10. 3 hits.
InterProIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR012954. BP28_C_dom.
IPR021133. HEAT_type_2.
IPR022125. U3snoRNP10.
[Graphical view]
PfamPF08146. BP28CT. 1 hit.
PF12397. U3snoRNP10. 1 hit.
[Graphical view]
SMARTSM01036. BP28CT. 1 hit.
[Graphical view]
SUPFAMSSF48371. SSF48371. 6 hits.
PROSITEPS50077. HEAT_REPEAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUTP10_CANAL
AccessionPrimary (citable) accession number: Q59ZX6
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: April 26, 2005
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Candida albicans

Candida albicans: entries and gene names