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Q59ZV4 (BNA7_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable kynurenine formamidase

EC=3.5.1.9
Alternative name(s):
Biosynthesis of nicotinic acid protein 7
Probable N-formylkynurenine formamidase
Gene names
Name:BNA7
ORF Names:CaO19.7237
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the conversion of tryptophan to nicotinic acid, NAD(H) and NADP(H) By similarity.

Catalytic activity

N-formyl-L-kynurenine + H2O = formate + L-kynurenine.

Pathway

Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.

Sequence similarities

Belongs to the BNA7 family.

Ontologies

Keywords
   Biological processTryptophan catabolism
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological processtryptophan catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionarylformamidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Probable kynurenine formamidase
PRO_0000361881

Sites

Active site371 Potential
Active site1041 Potential

Sequences

Sequence LengthMass (Da)Tools
Q59ZV4 [UniParc].

Last modified April 26, 2005. Version 1.
Checksum: 4E1B92AE06554649

FASTA26730,609
        10         20         30         40         50         60 
MEDISEEQEF KYGEHSLQKI KVFKYSSTNA STYIYIHGGA WRDPSNTFDE MRPVLGIPNA 

        70         80         90        100        110        120 
NLIGINYRLS PEIKHPEHLI DILRALRFVK QNFDVSQITL LGHSVGATMI LQLLHYRQII 

       130        140        150        160        170        180 
RDGLKHTHKD DLSSLDNLFA YVNDNVLLSQ VIFLDGIYDV VELLKEYPDY ASFVDDAFVS 

       190        200        210        220        230        240 
NKHFADSTQL SSANESLDLP FSLVSKDTKF LIYQSLEDDL LSMKQTHLLI DYLSSKNQGF 

       250        260 
TLHVGNWGKH EEIFGKYREI VFSGNVP 

« Hide

References

[1]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AACQ01000092 Genomic DNA. Translation: EAK95999.1.
RefSeqXP_715037.1. XM_709944.1.

3D structure databases

ProteinModelPortalQ59ZV4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3643309.
KEGGcal:CaO19.7237.

Organism-specific databases

CGDCAL0003841. orf19.7237.

Phylogenomic databases

OMANTHSANV.
PhylomeDBQ59ZV4.

Family and domain databases

InterProIPR013094. AB_hydrolase_3.
[Graphical view]
KOK14263.
PfamPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBNA7_CANAL
AccessionPrimary (citable) accession number: Q59ZV4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: April 26, 2005
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families